topics for research paper in organic chemistry

Organic Chemistry Research Paper Topics

• Carbon family
• Fermentation
• Hydrologic cycle
• Natural gas
• Nitrogen cycle
• Nitrogen family
• Oxygen family

In 1828, German chemist Friedrich Wöhler (1800–1882) proved that this theory of vitalism was untrue. He found a very simple way to convert chemical compounds from living organisms into comparable compounds from nonliving entities.

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As a result of Wöhler’s research, the definition of organic chemistry changed. The new definition was based on the observation that every compound discovered in living organisms had one property in common: they all contained the element carbon. As a result, the modern definition of organic chemistry—as the study of carbon compounds—was adopted.

Organic and Inorganic Chemistry

One important point that Wöhler’s research showed was that the principles and techniques of chemistry apply equally well to compounds found in living organisms and in nonliving things. Nonetheless, some important differences between organic and inorganic (not organic) compounds exist. These include the following:

• The number of organic compounds vastly exceeds the number of inorganic compounds. The ratio of carbon-based compounds to noncarbon- based compounds is at least ten to one, with close to 10 million organic compounds known today. The reason for this dramatic difference is a special property of the carbon atom: its ability to join with other carbon atoms in very long chains, in rings, and in other kinds of geometric arrangements. It is not at all unusual for dozens, hundreds, or thousands of carbon atoms to bond to each other within a single compound—a property that no other element exhibits.
• In general, organic compounds tend to have much lower melting and boiling points than do inorganic compounds.
• In general, organic compounds are less likely to dissolve in water than are inorganic compounds.
• Organic compounds are likely to be more flammable but poorer conductors of heat and electricity than are inorganic compounds.
• Organic reactions tend to take place more slowly and to produce a much more complex set of products than do inorganic reactions.

Functional Groups and Organic Families

The huge number of organic compounds requires that some system be developed for organizing them. The criterion on which those compounds are organized is the presence of various functional groups. A functional group is an arrangement of atoms that is responsible for certain characteristic physical and chemical properties in a compound. For example, one such functional group is the hydroxyl group, consisting of an oxygen atom and hydrogen atom joined to each other. It is represented by the formula -OH.

All organic compounds with the same functional group are said to belong to the same organic family. Any organic compound that contains a hydroxyl group, for instance, is called an alcohol. All alcohols are similar to each other in that: (1) they contain one or more hydroxyl groups, and (2) because of those groups, they have similar physical and chemical properties. For example, alcohols tend to be more soluble in water than other organic compounds because the hydroxyl groups in the alcohol form bonds with water molecules.

The simplest organic compounds are the hydrocarbons, compounds that contain only two elements: carbon and hydrogen. The class of hydrocarbons can be divided into subgroups depending on the way in which carbon and hydrogen atoms are joined to each other. In some hydrocarbons, for example, carbon and hydrogen atoms are joined to each other only by single bonds. A single bond is a chemical bond that consists of a pair of electrons. Such hydrocarbons are known as saturated hydrocarbons.

In other hydrocarbons, carbon and hydrogen atoms are joined to each other by double or triple bonds. A double bond consists of two pairs of electrons, and a triple bond consists of three pairs of electrons. Hydrocarbons containing double and triple bonds are said to be unsaturated.

Hydrocarbons can also be open-chain or ring compounds. In an open-chain hydrocarbon, the carbon atoms are all arranged in a straight line, like a strand of spaghetti. In a ring hydrocarbon, the carbons are arranged in a continuous loop, such as a square, a pentagon, or a triangle.

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Themed collection Most popular 2022 organic chemistry articles

Umpolung strategies for the functionalization of peptides and proteins

This perspective highlights the growing body of literature that leverages polarity reversal (umpolung reactivity) for the selective modification of proteinogenic functionalities and identifies opportunities for further innovation.

Photocatalytic C(sp 3 ) radical generation via C–H, C–C, and C–X bond cleavage

C(sp 3 ) radicals (R˙) are of broad research interest and synthetic utility.

H-bond cooperativity: polarisation effects on secondary amides

Formation of an intramolecular phenol-amide H-bond leads to a dramatic increase in the H-bond donor strength of the amide NH group. Polarisation of the amide group is directly proportional to the polarity of the phenol H-bond donor.

Fast relaxing red and near-IR switchable azobenzenes with chalcogen and halogen substituents: periodic trends, tuneable thermal half-lives and chalcogen bonding

The synthesis of red-shifted azobenzenes functionalised with heavy chalcogen and halogen substituents is reported, enabling photo-switching with red and near IR light and Z → E thermal isomerization rates spanning seven orders of magnitude.

BQ-AurIPr: a redox-active anticancer Au( I ) complex that induces immunogenic cell death

A redox-active anticancer Au( I ) complex that induces immunogenic cell death in non-small cell lung cancer cells has been identified. Mitochondrial oxidative stress leading to mitophagy-dependent secretion of various DAMPs is implicated as the main mechanism inducing ICD.

Discovery of novel drug-like antitubercular hits targeting the MEP pathway enzyme DXPS by strategic application of ligand-based virtual screening

We identified two drug-like antitubercular hits with submicromolar inhibition constants against the target 1-deoxy- D -xylulose-5-phosphate synthase (DXPS) with a new mode of action and promising activity against drug-resistant tuberculosis.

Highly contorted superhelicene hits near-infrared circularly polarized luminescence

This twisted superhelicene employed its twists and loops to shine chiral emission into the NIR region. The proof of its promising applicability in optoelectronic devices is the analogous chiroptical properties obtained in solution and thin films.

Ferroptosis promotes sonodynamic therapy: a platinum( II )–indocyanine sonosensitizer

A novel platinum( II )–cyanine complex showed a greater excellent sonodynamic therapeutic effect than photodynamic therapy in vivo . This work expands the biological applications of metal complexes from traditional photodynamic therapy to sonodynamic therapy.

Non-directed Pd-catalysed electrooxidative olefination of arenes

The Fujiwara–Moritani reaction using electric current is a powerful tool for the olefination of arenes by Pd-catalysed C–H activation.

Subphthalocyanine capsules: molecular reactors for photoredox transformations of fullerenes

A photoredox cage built by coordination of two pyridyl-subphthalocyanines to Pd centers has proved versatile and efficient to catalyze photoredox addition reactions over encapsulated C 60 .

Iridium-catalyzed α-selective deuteration of alcohols

An α-selective, iridium( III )-bipyridonate-catalyzed hydrogen isotope exchange of alcohols using D 2 O has been developed for the direct, chemoselective deuteration of primary and secondary alcohols, thereby providing deuterated bioactive molecules.

Catalytic defluorinative ketyl–olefin coupling by halogen-atom transfer

A catalytic ketyl–olefin coupling reaction including sequentially orchestrated Lewis acid activation, halogen-atom transfer, radical addition, single-electron reduction and β-fluoro elimination has been developed.

Zn( II )-Coordination-driven self-assembled nanoagents for multimodal imaging-guided photothermal/gene synergistic therapy

siRNA@PT-ZIF-8 was prepared by one pot self-assembly for tri-mode imaging guided mild-temperature photothermal synergetic gene therapy.

General electrochemical Minisci alkylation of N -heteroarenes with alkyl halides

Herein, we report, a general, facile and environmentally friendly Minisci-type alkylation of N -heteroarenes under simple and straightforward electrochemical conditions using widely available alkyl halides as radical precursors.

Customising excitation properties of polycyclic aromatic hydrocarbons by rational positional heteroatom doping: the peri -xanthenoxanthene ( PXX ) case

In this paper we tackle the challenge of gaining control of the photophysical properties of PAHs through a site-specific N-doping within the structural aromatic framework.

A practical and sustainable two-component Minisci alkylation via photo-induced EDA-complex activation

An operationally simple, open-air, and efficient light-mediated Minisci C–H alkylation method is described, based on the formation of an electron donor–acceptor (EDA) complex between nitrogen-containing heterocycles and redox-active esters.

A sequential cyclization/π-extension strategy for modular construction of nanographenes enabled by stannole cycloadditions

Stannoles are introduced as a new, spontaneously aromatizing diene for [4 + 2] cycloadditions that can be easily introduced into diverse conjugated systems, facilitating the efficient synthesis of complex PAHs and their π-extension.

Functional group divergence and the structural basis of acridine photocatalysis revealed by direct decarboxysulfonylation

Carboxylic acids can now serve as a single point of entry to several sulfonyl functional groups by a one-step organophotocatalytic sulfonylation, revealing structural effects that enable the photocatalysis.

An integrated platform approach enables discovery of potent, selective and ligand-competitive cyclic peptides targeting the GIP receptor

mRNA display generates vast datasets of protein binders. Bioinformatic clustering of the sequences combined with high throughput synthesis and analysis methods allow efficient prioritisation of hits for in vivo experiments.

NHC and visible light-mediated photoredox co-catalyzed 1,4-sulfonylacylation of 1,3-enynes for tetrasubstituted allenyl ketones

Unprecedented NHC and photocatalysis co-catalyzed radical 1,4-sulfonylacylation of 1,3-enynes has been realized, providing structurally diversified tetrasubstituted allenyl ketones via allenyl and ketyl radical cross-coupling.

Selective covalent targeting of SARS-CoV-2 main protease by enantiopure chlorofluoroacetamide

Chlorofluoroacetamide (CFA) was used as the warhead for covalent targeting of SARS-CoV-2 M pro . The chirality at CFA showed marked influence on inhibitory activity, suggesting stereospecific activation of CFA for cysteine modification in the protein.

Electrooxidative palladium- and enantioselective rhodium-catalyzed [3 + 2] spiroannulations

Despite indisputable progress in the development of electrochemical transformations, electrocatalytic annulations for the synthesis of biologically relevant three-dimensional spirocyclic compounds has as of yet not been accomplished.

Pressing matter: why are ionic liquids so viscous?

We use an experimental approach to compare an ionic liquid with a molecular mimic, focusing on viscosities. Charge network and coulombic compaction contribute significantly to the high viscosity of ionic liquids; we discuss the implications on their design and optimisation.

Suzuki-type cross-coupling of alkyl trifluoroborates with acid fluoride enabled by NHC/photoredox dual catalysis

An acylative Suzuki-type cross-coupling of alkyl trifluoroborates and acid fluorides was developed by merging NHC organocatalysis with photoredox catalysis. A broad spectrum of ketones could be facilely synthesised under mild reaction conditions.

Retaining the structural integrity of disulfide bonds in diphtheria toxoid carrier protein is crucial for the effectiveness of glycoconjugate vaccine candidates

The introduction of glycoconjugate vaccines marks an important point in the fight against various infectious diseases.

Prediction of protein p K a with representation learning

We developed new empirical ML model for protein p K a prediction with MAEs below 0.5 for all amino acid types.

Enhanced N-directed electrophilic C–H borylation generates BN–[5]- and [6]helicenes with improved photophysical properties

An enhanced N-directed electrophilic C–H borylation methodology has been developed that provides access to azaborine containing helicenes.

About this collection

This specially curated collection pulls together some of the most popular articles from 2022 in the field of organic chemistry. The collection presents some outstanding contributions to the field, ranging from photocatalytic radical generation to prediction of protein pKa, and as with all Chemical Science articles – they are all completely free to access and read. We hope you enjoy browsing through this collection.

If a particular article has inspired you, do feel free to share on social media using the buttons on each article landing page and use our hashtag: #ChemSciMostPopular

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50 Research Ideas in Organic Chemistry

Unlocking the Potential: 50 Intriguing Organic Chemistry Research Ideas

Table of contents

50 intriguing organic chemistry research ideas.

In the world of science, organic chemistry is like the hidden language of life. It’s the study of carbon and its dance with other elements to create everything from medicines that heal to materials that make our world. Today, iLovePhD delves into 50 intriguing research ideas in this fascinating field, uncovering the secrets and innovations that drive progress in science.

• Green Synthesis of Organic Compounds : Explore eco-friendly methods for synthesizing organic molecules.
• Applications of Organometallic Chemistry : Discuss the use of organometallic compounds in catalysis and materials science.
• Designing Sustainable Polymers : Investigate the development of biodegradable and recyclable polymers.
• Catalytic Asymmetric Synthesis : Examine recent advances in creating chiral organic compounds.
• Supramolecular Chemistry in Drug Design : Discuss how non-covalent interactions can be harnessed for drug discovery.
• Functionalization of C-H Bonds : Explore methods for selectively functionalizing carbon-hydrogen bonds.
• Natural Product Synthesis : Highlight recent total syntheses of complex natural products.
• Electroorganic Chemistry : Discuss the use of electricity as a reagent in organic reactions.
• Molecular Machines : Explore the design and applications of synthetic molecular machines.
• Metal-Organic Frameworks (MOFs) : Investigate the use of MOFs in gas storage and separation.
• Enzyme Mimicry in Catalysis : Discuss synthetic catalysts that mimic enzyme behavior.
• Chemical Biology : Explore the interface between chemistry and biology for drug discovery.
• Organic Photovoltaics : Discuss the development of organic materials for solar cells.
• Peptide Chemistry : Investigate the synthesis and applications of peptides in drug design.
• Click Chemistry : Highlight the versatility of click reactions in organic synthesis.
• Chemoinformatics : Discuss the use of computational methods in organic chemistry.
• Bioorthogonal Chemistry : Explore reactions that are compatible with living systems.
• Green Solvents in Organic Synthesis : Examine environmentally friendly solvents for organic reactions.
• Nanocatalysis : Discuss the role of nanoparticles in catalytic processes.
• Fluorine Chemistry : Investigate the unique properties of fluorinated organic compounds.
• Carbohydrate Chemistry : Explore the synthesis and functions of carbohydrates.
• Chemical Sensors : Discuss the design of organic sensors for detecting analytes.
• Synthetic Biology : Explore the engineering of biological systems for chemical production.
• Organic Chemistry in Medicine : Highlight the role of organic chemistry in drug development.
• Heterocyclic Chemistry : Investigate the synthesis and reactivity of heterocycles.
• Chemistry of Aromatics : Discuss reactions and applications of aromatic compounds.
• Polycyclic Aromatic Hydrocarbons (PAHs) : Explore the environmental and health impact of PAHs.
• Green Extraction Methods : Investigate eco-friendly techniques for extracting natural products.
• Organic Chemistry in Food : Discuss the chemistry behind food flavor and preservation.
• Chemistry of Natural Dyes : Explore the use of organic compounds as dyes.
• Artificial Sweeteners : Investigate the chemistry of sugar substitutes.
• Chemistry of Medicinal Plants : Highlight the organic compounds found in medicinal plants.
• Organic Synthesis with Flow Chemistry : Discuss continuous-flow methods in organic synthesis.
• Stereochemistry : Explore the importance of stereochemistry in organic reactions.
• Chirality in Pharmaceuticals : Discuss the role of chirality in drug design.
• Green Chemistry Metrics : Investigate metrics for assessing the sustainability of organic reactions.
• Photochemistry : Explore the use of light in driving organic reactions.
• Chemistry of Natural Toxins : Highlight the structures and effects of natural toxins.
• Chemistry of Pharmaceuticals : Discuss the synthesis and mechanisms of action of common drugs.
• Organic Chemistry in Cosmetics : Explore the chemistry of cosmetic products.
• Organic Chemistry in Art Conservation : Investigate the role of organic chemistry in preserving artworks.
• Radical Chemistry : Discuss the use of radicals in organic synthesis.
• Chemistry of Terpenes : Explore the diverse structures and functions of terpenes.
• Organic Chemistry of Vitamins : Highlight the organic compounds essential for health.
• Biocatalysis : Discuss the use of enzymes in organic synthesis.
• Chemistry of Lipids : Investigate the structure and functions of lipids.
• Chemistry of Amino Acids : Explore the building blocks of proteins.
• Chemistry of DNA : Discuss the structure and chemical properties of DNA.
• Nucleic Acid Chemistry : Investigate the synthesis and modification of nucleic acids.
• Organic Chemistry in Environmental Remediation : Highlight the use of organic compounds for cleaning up pollutants.

In closing, organic chemistry isn’t just about molecules; it’s about endless possibilities. These 50 research ideas showcase the diverse avenues researchers explore , from green synthesis to life-saving drugs. As we continue to unravel the mysteries of carbon, we can look forward to a future where science and innovation walk hand in hand, shaping a brighter world for us all.

• Aromatic chemistry
• Biocatalysis
• Bioorthogonal reactions
• Carbon compounds
• Catalysis Sustainable polymers
• Chiral compounds Chemical biology
• Click chemistry Computational chemistry
• DNA chemistry
• Drug discovery
• Environmental remediation
• Flow chemistry Stereochemistry
• Green metrics
• Green solvents
• Green synthesis
• Nanocatalysis Heterocyclic compounds
• Organic Chemistry
• Organic photovoltaics
• Peptide synthesis
• Photochemistry
• Research Ideas
• Supramolecular chemistry
• Terpenes Vitamins

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Home » 300+ Chemistry Research Topics

300+ Chemistry Research Topics

Table of Contents

Chemistry is a fascinating and complex field that explores the composition, properties, and behavior of matter at the molecular and atomic level. As a result, there are numerous chemistry research topics that can be explored, ranging from the development of new materials and drugs to the study of natural compounds and the environment. In this rapidly evolving field, researchers are constantly uncovering new insights and pushing the boundaries of our understanding of chemistry. Whether you are a student, a professional researcher, or simply curious about the world around you, there is always something new to discover in the field of chemistry. In this post, we will explore some of the exciting and important research topics in chemistry today.

Chemistry Research Topics

Chemistry Research Topics are as follows:

Organic Chemistry Research Topics

Organic Chemistry Research Topics are as follows:

• Development of novel synthetic routes for the production of biologically active natural products
• Investigation of reaction mechanisms and kinetics for organic transformations
• Design and synthesis of new catalysts for asymmetric organic reactions
• Synthesis and characterization of chiral compounds for pharmaceutical applications
• Development of sustainable methods for the synthesis of organic molecules using renewable resources
• Discovery of new reaction pathways for the conversion of biomass into high-value chemicals
• Study of molecular recognition and host-guest interactions for drug design
• Design and synthesis of new materials for energy storage and conversion
• Development of efficient and selective methods for C-H functionalization reactions
• Exploration of the reactivity of reactive intermediates such as radicals and carbenes
• Study of supramolecular chemistry and self-assembly of organic molecules
• Development of new methods for the synthesis of heterocyclic compounds
• Investigation of the biological activities and mechanisms of action of natural products
• Synthesis of polymeric materials with controlled architecture and functionality
• Development of new synthetic methodologies for the preparation of bioconjugates
• Investigation of the mechanisms of enzyme catalysis and the design of enzyme inhibitors
• Synthesis and characterization of novel fluorescent probes for biological imaging
• Development of new synthetic strategies for the preparation of carbohydrates and glycoconjugates
• Study of the properties and reactivity of carbon nanomaterials
• Design and synthesis of novel drugs for the treatment of diseases such as cancer, diabetes, and Alzheimer’s disease.

Inorganic Chemistry Research Topics

Inorganic Chemistry Research Topics are as follows:

• Synthesis and characterization of new metal-organic frameworks (MOFs) for gas storage and separation applications
• Development of new catalysts for sustainable chemical synthesis reactions
• Investigation of the electronic and magnetic properties of transition metal complexes for spintronics applications
• Synthesis and characterization of novel nanomaterials for energy storage applications
• Development of new ligands for metal coordination complexes with potential medical applications
• Investigation of the mechanism of metal-catalyzed reactions using advanced spectroscopic techniques
• Synthesis and characterization of new inorganic materials for photocatalytic water splitting
• Development of new materials for electrochemical carbon dioxide reduction reactions
• Investigation of the properties of transition metal oxides for energy storage and conversion applications
• Synthesis and characterization of new metal chalcogenides for optoelectronic applications
• Development of new methods for the preparation of inorganic nanoparticles with controlled size and shape
• Investigation of the reactivity and catalytic properties of metal clusters
• Synthesis and characterization of new metal-organic polyhedra (MOPs) for gas storage and separation applications
• Development of new methods for the synthesis of metal nanoparticles using environmentally friendly reducing agents
• Investigation of the properties of metal-organic frameworks for gas sensing applications
• Synthesis and characterization of new coordination polymers with potential magnetic and electronic properties
• Development of new materials for electrocatalytic water oxidation reactions
• Investigation of the properties of metal-organic frameworks for carbon capture and storage applications
• Synthesis and characterization of new metal-containing polymers with potential applications in electronics and energy storage
• Development of new methods for the synthesis of metal-organic frameworks using green solvents and renewable resources.

Physical Chemistry Research Topics

Physical Chemistry Research Topics are as follows:

• Investigation of the properties and interactions of ionic liquids in aqueous and non-aqueous solutions.
• Development of advanced analytical techniques for the study of protein structure and dynamics.
• Investigation of the thermodynamic properties of supercritical fluids for use in industrial applications.
• Development of novel nanomaterials for energy storage applications.
• Studies of the surface chemistry of catalysts for the optimization of their performance in chemical reactions.
• Development of new methods for the synthesis of complex organic molecules with improved yields and selectivity.
• Investigation of the molecular mechanisms involved in the catalysis of biochemical reactions.
• Development of new strategies for the controlled release of drugs and other bioactive molecules.
• Studies of the interaction of nanoparticles with biological systems for biomedical applications.
• Investigation of the thermodynamic properties of materials under extreme conditions of temperature and pressure.
• Development of new methods for the characterization of materials at the nanoscale.
• Investigation of the electronic and magnetic properties of materials for use in spintronics.
• Development of new materials for energy conversion and storage.
• Studies of the kinetics and thermodynamics of adsorption processes on surfaces.
• Investigation of the transport properties of ionic liquids for use in energy storage and conversion devices.
• Development of new materials for the capture and sequestration of greenhouse gases.
• Studies of the structure and properties of biomolecules for use in drug design and development.
• Investigation of the dynamics of chemical reactions in solution using time-resolved spectroscopic techniques.
• Development of new approaches for the synthesis of metallic and semiconductor nanoparticles with controlled size and shape.
• Studies of the structure and properties of materials for use in electrochemical energy storage devices.

Analytical Chemistry Research Topics

Analytical Chemistry Research Topics are as follows:

• Development and optimization of analytical techniques for the quantification of trace elements in food and environmental samples.
• Design and synthesis of novel analytical probes for the detection of biomolecules in complex matrices.
• Investigation of the fundamental mechanisms involved in the separation and detection of complex mixtures using chromatographic techniques.
• Development of sensors and biosensors for the detection of chemical and biological species in real-time.
• Investigation of the chemical and structural properties of nanomaterials and their applications in analytical chemistry.
• Development and validation of analytical methods for the quantification of contaminants and pollutants in water, air, and soil.
• Investigation of the molecular mechanisms underlying drug metabolism and toxicity using mass spectrometry.
• Development of analytical tools for the identification and quantification of drugs of abuse in biological matrices.
• Investigation of the chemical composition and properties of natural products and their applications in medicine and food science.
• Development of advanced analytical techniques for the characterization of proteins and peptides.
• Investigation of the chemistry and mechanism of action of antioxidants in foods and their impact on human health.
• Development of analytical methods for the detection and quantification of microorganisms in food and environmental samples.
• Investigation of the molecular mechanisms involved in the biosynthesis and degradation of important biomolecules such as proteins, carbohydrates, and lipids.
• Development of analytical methods for the detection and quantification of environmental toxins and their impact on human health.
• Investigation of the structure and properties of biological membranes and their role in drug delivery and disease.
• Development of analytical techniques for the characterization of complex mixtures such as petroleum and crude oil.
• Investigation of the chemistry and mechanism of action of natural and synthetic dyes.
• Development of analytical techniques for the detection and quantification of pharmaceuticals and personal care products in water and wastewater.
• Investigation of the chemical composition and properties of biopolymers and their applications in biomedicine and biomaterials.
• Development of analytical methods for the identification and quantification of essential nutrients and vitamins in food and dietary supplements.

Biochemistry Research Topics

Biochemistry Research Topics are as follows:

• The role of enzymes in metabolic pathways
• The biochemistry of DNA replication and repair
• Protein folding and misfolding diseases
• Lipid metabolism and the pathogenesis of atherosclerosis
• The role of vitamins and minerals in human metabolism
• Biochemistry of cancer and the development of targeted therapies
• The biochemistry of signal transduction pathways and their regulation
• The mechanisms of antibiotic resistance in bacteria
• The biochemistry of neurotransmitters and their roles in behavior and disease
• The role of oxidative stress in aging and age-related diseases
• The biochemistry of microbial fermentation and its applications in industry
• The biochemistry of the immune system and its response to pathogens
• The biochemistry of plant metabolism and its regulation
• The molecular basis of genetic diseases and gene therapy
• The biochemistry of membrane transport and its role in cell function
• The biochemistry of muscle contraction and its regulation
• The role of lipids in membrane structure and function
• The biochemistry of photosynthesis and its regulation
• The biochemistry of RNA splicing and alternative splicing events
• The biochemistry of epigenetics and its regulation in gene expression.

Environmental Chemistry Research Topics

Environmental Chemistry Research Topics are as follows:

• Investigating the effects of microplastics on aquatic ecosystems and their potential impact on human health.
• Examining the impact of climate change on soil quality and nutrient availability in agricultural systems.
• Developing methods to improve the removal of heavy metals from contaminated soils and waterways.
• Assessing the effectiveness of natural and synthetic antioxidants in mitigating the effects of air pollution on human health.
• Investigating the potential for using algae and other microorganisms to sequester carbon dioxide from the atmosphere.
• Studying the role of biodegradable plastics in reducing plastic waste and their impact on the environment.
• Examining the impact of pesticides and other agricultural chemicals on water quality and the health of aquatic organisms.
• Investigating the effects of ocean acidification on marine organisms and ecosystems.
• Developing new materials and technologies to reduce carbon emissions from industrial processes.
• Evaluating the effectiveness of phytoremediation in cleaning up contaminated soils and waterways.
• Studying the impact of microplastics on terrestrial ecosystems and their potential to enter the food chain.
• Developing sustainable methods for managing and recycling electronic waste.
• Investigating the role of natural processes, such as weathering and erosion, in regulating atmospheric carbon dioxide levels.
• Assessing the impact of urbanization on air quality and developing strategies to mitigate pollution in cities.
• Examining the effects of climate change on the distribution and abundance of species in different ecosystems.
• Investigating the impact of ocean currents on the distribution of pollutants and other environmental contaminants.
• Developing new materials and technologies for renewable energy generation and storage.
• Studying the effects of deforestation on soil quality, water availability, and biodiversity.
• Assessing the potential for using waste materials, such as agricultural residues and municipal solid waste, as sources of renewable energy.
• Investigating the role of natural and synthetic chemicals in regulating ecosystem functions, such as nutrient cycling and carbon sequestration.

Polymer Chemistry Research Topics

Polymer Chemistry Research Topics are as follows:

• Development of new monomers for high-performance polymers
• Synthesis and characterization of biodegradable polymers for sustainable packaging
• Design of stimuli-responsive polymers for drug delivery applications
• Investigation of the properties and applications of conductive polymers
• Development of new catalysts for controlled/living polymerization
• Synthesis of polymers with tailored mechanical properties
• Characterization of the structure-property relationship in polymer nanocomposites
• Study of the impact of polymer architecture on material properties
• Design and synthesis of new polymeric materials for energy storage
• Development of high-throughput methods for polymer synthesis and characterization
• Exploration of new strategies for polymer recycling and upcycling
• Synthesis and characterization of responsive polymer networks for smart textiles
• Design of advanced polymer coatings with self-healing properties
• Investigation of the impact of processing conditions on the morphology and properties of polymer materials
• Study of the interactions between polymers and biological systems
• Development of biocompatible polymers for tissue engineering applications
• Synthesis and characterization of block copolymers for advanced membrane applications
• Exploration of the potential of polymer-based sensors and actuators
• Design of novel polymer electrolytes for advanced batteries and fuel cells
• Study of the behavior of polymers under extreme conditions, such as high pressure or temperature.

Materials Chemistry Research Topics

Materials Chemistry Research Topics are as follows:

• Development of new advanced materials for energy storage and conversion
• Synthesis and characterization of nanomaterials for environmental remediation
• Design and fabrication of stimuli-responsive materials for drug delivery
• Investigation of electrocatalytic materials for fuel cells and electrolysis
• Fabrication of flexible and stretchable electronic materials for wearable devices
• Development of novel materials for high-performance electronic devices
• Exploration of organic-inorganic hybrid materials for optoelectronic applications
• Study of corrosion-resistant coatings for metallic materials
• Investigation of biomaterials for tissue engineering and regenerative medicine
• Synthesis and characterization of metal-organic frameworks for gas storage and separation
• Design and fabrication of new materials for water purification
• Investigation of carbon-based materials for supercapacitors and batteries
• Synthesis and characterization of self-healing materials for structural applications
• Development of new materials for catalysis and chemical reactions
• Exploration of magnetic materials for spintronic devices
• Investigation of thermoelectric materials for energy conversion
• Study of 2D materials for electronic and optoelectronic applications
• Development of sustainable and eco-friendly materials for packaging
• Fabrication of advanced materials for sensors and actuators
• Investigation of materials for high-temperature applications such as aerospace and nuclear industries.

Nuclear Chemistry Research Topics

Nuclear Chemistry Research Topics are as follows:

• Nuclear fission and fusion reactions
• Nuclear power plant safety and radiation protection
• Radioactive waste management and disposal
• Nuclear fuel cycle and waste reprocessing
• Nuclear energy and its impact on climate change
• Radiation therapy for cancer treatment
• Radiopharmaceuticals for medical imaging
• Nuclear medicine and its role in diagnostics
• Nuclear forensics and nuclear security
• Isotopic analysis in environmental monitoring and pollution control
• Nuclear magnetic resonance (NMR) spectroscopy
• Nuclear magnetic resonance imaging (MRI)
• Radiation damage in materials and radiation effects on electronic devices
• Nuclear data evaluation and validation
• Nuclear reactors design and optimization
• Nuclear fuel performance and irradiation behavior
• Nuclear energy systems integration and optimization
• Neutron and gamma-ray detection and measurement techniques
• Nuclear astrophysics and cosmology
• Nuclear weapons proliferation and disarmament.

Medicinal Chemistry Research Topics

Medicinal Chemistry Research Topics are as follows:

• Drug discovery and development
• Design and synthesis of novel drugs
• Medicinal chemistry of natural products
• Structure-activity relationships (SAR) of drugs
• Rational drug design using computational methods
• Target identification and validation
• Drug metabolism and pharmacokinetics (DMPK)
• Drug delivery systems
• Development of new antibiotics
• Design of drugs for the treatment of cancer
• Development of drugs for the treatment of neurological disorders
• Medicinal chemistry of peptides and proteins
• Development of drugs for the treatment of infectious diseases
• Discovery of new antiviral agents
• Design of drugs for the treatment of cardiovascular diseases
• Medicinal chemistry of enzyme inhibitors
• Development of drugs for the treatment of inflammatory diseases
• Design of drugs for the treatment of metabolic disorders
• Medicinal chemistry of anti-cancer agents
• Development of drugs for the treatment of rare diseases.

Food Chemistry Research Topics

Food Chemistry Research Topics are as follows:

• Investigating the effect of cooking methods on the nutritional value of food.
• Analyzing the role of antioxidants in preventing food spoilage and degradation.
• Examining the effect of food processing techniques on the nutritional value of fruits and vegetables.
• Studying the chemistry of food additives and their impact on human health.
• Evaluating the role of enzymes in food digestion and processing.
• Investigating the chemical properties and functional uses of food proteins.
• Analyzing the effect of food packaging materials on the quality and safety of food products.
• Examining the chemistry of food flavorings and the impact of flavor on consumer acceptance.
• Studying the role of carbohydrates in food texture and structure.
• Investigating the chemistry of food lipids and their impact on human health.
• Analyzing the chemical properties and functional uses of food gums and emulsifiers.
• Examining the effect of processing on the flavor and aroma of food products.
• Studying the chemistry of food preservatives and their impact on food safety.
• Investigating the chemical properties and functional uses of food fibers.
• Analyzing the effect of food processing on the bioavailability of nutrients.
• Examining the chemistry of food colorants and their impact on consumer acceptance.
• Studying the role of vitamins and minerals in food and their impact on human health.
• Investigating the chemical properties and functional uses of food hydrocolloids.
• Analyzing the effect of food processing on the allergenicity of food products.
• Examining the chemistry of food sweeteners and their impact on human health.

Industrial Chemistry Research Topics

Industrial Chemistry Research Topics are as follows:

• Development of catalysts for selective hydrogenation reactions in the petrochemical industry.
• Green chemistry approaches for the synthesis of biodegradable polymers from renewable sources.
• Optimization of solvent extraction processes for the separation of rare earth elements from ores.
• Development of novel materials for energy storage applications, such as lithium-ion batteries.
• Production of biofuels from non-food sources, such as algae or waste biomass.
• Application of computational chemistry to optimize the design of new catalysts and materials.
• Design and optimization of continuous flow processes for large-scale chemical production.
• Development of new synthetic routes for the production of pharmaceutical intermediates.
• Investigation of the environmental impact of industrial processes and development of sustainable alternatives.
• Development of innovative water treatment technologies for industrial wastewater.
• Synthesis of functionalized nanoparticles for use in drug delivery and other biomedical applications.
• Optimization of processes for the production of high-performance polymers, such as polyamides or polyesters.
• Design and optimization of process control strategies for efficient and safe chemical production.
• Development of new methods for the detection and removal of heavy metal ions from industrial effluents.
• Investigation of the behavior of surfactants in complex mixtures, such as crude oil or food products.
• Development of new materials for catalytic oxidation reactions, such as the removal of volatile organic compounds from air.
• Investigation of the properties and behavior of materials under extreme conditions, such as high pressure or high temperature.
• Development of new processes for the production of chemicals from renewable resources, such as bio-based building blocks.
• Study of the kinetics and mechanism of chemical reactions in complex systems, such as multi-phase reactors.
• Optimization of the production of fine chemicals, such as flavors and fragrances, using biocatalytic processes.

Computational Chemistry Research Topics

Computational Chemistry Research Topics are as follows:

• Development and application of machine learning algorithms for predicting chemical reactions and properties.
• Investigation of the role of solvents in chemical reactions using molecular dynamics simulations.
• Modeling and simulation of protein-ligand interactions to aid drug design.
• Study of the electronic structure and reactivity of catalysts for sustainable energy production.
• Analysis of the thermodynamics and kinetics of complex chemical reactions using quantum chemistry methods.
• Exploration of the mechanism and kinetics of enzyme-catalyzed reactions using molecular dynamics simulations.
• Investigation of the properties and behavior of nanoparticles using computational modeling.
• Development of computational tools for the prediction of chemical toxicity and environmental impact.
• Study of the electronic properties of graphene and other 2D materials for applications in electronics and energy storage.
• Investigation of the mechanisms of protein folding and aggregation using molecular dynamics simulations.
• Development and optimization of computational methods for calculating thermodynamic properties of liquids and solids.
• Study of the properties of supercritical fluids for applications in separation and extraction processes.
• Development of new methods for the calculation of electron transfer rates in complex systems.
• Investigation of the electronic and mechanical properties of carbon nanotubes for applications in nanoelectronics and nanocomposites.
• Development of new approaches for modeling the interaction of biomolecules with biological membranes.
• Study of the mechanisms of charge transfer in molecular and hybrid solar cells.
• Analysis of the structural and mechanical properties of materials under extreme conditions using molecular dynamics simulations.
• Development of new approaches for the calculation of free energy differences in complex systems.
• Investigation of the reaction mechanisms of metalloenzymes using quantum mechanics/molecular mechanics (QM/MM) methods.
• Study of the properties of ionic liquids for applications in catalysis and energy storage.

Theoretical Chemistry Research Topics

Theoretical Chemistry Research Topics are as follows:

• Quantum Chemical Studies of Excited State Processes in Organic Molecules
• Theoretical Investigation of Structure and Reactivity of Metal-Organic Frameworks
• Computational Modeling of Reaction Mechanisms and Kinetics in Enzyme Catalysis
• Theoretical Investigation of Non-Covalent Interactions in Supramolecular Chemistry
• Quantum Chemical Studies of Photochemical Processes in Organic Molecules
• Theoretical Analysis of Charge Transport in Organic and Inorganic Materials
• Computational Modeling of Protein Folding and Dynamics
• Quantum Chemical Investigations of Electron Transfer Processes in Complex Systems
• Theoretical Studies of Surface Chemistry and Catalysis
• Computational Design of Novel Materials for Energy Storage Applications
• Theoretical Analysis of Chemical Bonding and Molecular Orbital Theory
• Quantum Chemical Investigations of Magnetic Properties of Complex Systems
• Computational Modeling of Biological Membranes and Transport Processes
• Theoretical Studies of Nonlinear Optical Properties of Molecules and Materials
• Quantum Chemical Studies of Spectroscopic Properties of Molecules
• Theoretical Investigations of Reaction Mechanisms in Organometallic Chemistry
• Computational Modeling of Heterogeneous Catalysis
• Quantum Chemical Studies of Excited State Dynamics in Photosynthesis
• Theoretical Analysis of Chemical Reaction Networks
• Computational Design of Nanomaterials for Biomedical Applications

Astrochemistry Research Topics

Astrochemistry Research Topics are as follows:

• Investigating the chemical composition of protoplanetary disks and its implications for planet formation
• Examining the role of magnetic fields in the formation of complex organic molecules in space
• Studying the effects of interstellar radiation on the chemical evolution of molecular clouds
• Exploring the chemistry of comets and asteroids to better understand the early solar system
• Investigating the origin and evolution of interstellar dust and its relationship to organic molecules
• Examining the formation and destruction of interstellar molecules in shocked gas
• Studying the chemical processes that occur in the atmospheres of planets and moons in our solar system
• Exploring the possibility of life on other planets through astrobiology and astrochemistry
• Investigating the chemistry of planetary nebulae and their role in the evolution of stars
• Studying the chemical properties of exoplanets and their potential habitability
• Examining the chemical reactions that occur in the interstellar medium
• Investigating the chemical composition of supernova remnants and their impact on the evolution of galaxies
• Studying the chemical composition of interstellar grains and their role in the formation of stars and planets
• Exploring the chemistry of astrocytes and their role in the evolution of galaxies
• Investigating the formation of interstellar ice and its implications for the origin of life
• Examining the chemistry of molecular clouds and its relationship to star formation
• Studying the chemical composition of the interstellar medium in different galaxies and how it varies
• Investigating the role of cosmic rays in the formation of complex organic molecules in space
• Exploring the chemical properties of interstellar filaments and their relationship to star formation
• Studying the chemistry of protostars and the role of turbulence in the formation of stars.

Geochemistry Research Topics

Geochemistry Research Topics are as follows:

• Understanding the role of mineralogical and geochemical factors on metal mobility in contaminated soils
• Investigating the sources and fate of dissolved organic matter in aquatic systems
• Exploring the geochemical signatures of ancient sedimentary rocks to reconstruct Earth’s past atmospheric conditions
• Studying the impacts of land-use change on soil organic matter content and quality
• Investigating the impact of acid mine drainage on water quality and ecosystem health
• Examining the processes controlling the behavior and fate of emerging contaminants in the environment
• Characterizing the organic matter composition of shale gas formations to better understand hydrocarbon storage and migration
• Evaluating the potential for carbon capture and storage in geologic formations
• Investigating the geochemical processes controlling the formation and evolution of ore deposits
• Studying the geochemistry of geothermal systems to better understand energy production potential and environmental impacts
• Exploring the impacts of climate change on the biogeochemistry of terrestrial ecosystems
• Investigating the geochemical cycling of nutrients in coastal marine environments
• Characterizing the isotopic composition of minerals and fluids to understand Earth’s evolution
• Developing new analytical techniques to better understand the chemistry of natural waters
• Studying the impact of anthropogenic activities on the geochemistry of urban soils
• Investigating the role of microbial processes in geochemical cycling of elements in soils and sediments
• Examining the impact of wildfires on soil and water chemistry
• Characterizing the geochemistry of mineral dust and its impact on climate and biogeochemical cycles
• Investigating the geochemical factors controlling the release and transport of contaminants from mine tailings
• Exploring the biogeochemistry of wetlands and their role in carbon sequestration and nutrient cycling.

Electrochemistry Research Topics

Electrochemistry Research Topics are as follows:

• Development of high-performance electrocatalysts for efficient electrochemical conversion of CO2 to fuels and chemicals
• Investigation of electrode-electrolyte interfaces in lithium-ion batteries for enhanced battery performance and durability
• Design and synthesis of novel electrolytes for high-energy-density and stable lithium-sulfur batteries
• Development of advanced electrochemical sensors for the detection of trace-levels of analytes in biological and environmental samples
• Analysis of the electrochemical behavior of new materials and their electrocatalytic properties in fuel cells
• Study of the kinetics of electrochemical reactions and their effect on the efficiency and selectivity of electrochemical processes
• Development of novel strategies for the electrochemical synthesis of value-added chemicals from biomass and waste materials
• Analysis of the electrochemical properties of metal-organic frameworks (MOFs) for energy storage and conversion applications
• Investigation of the electrochemical degradation mechanisms of polymer electrolyte membranes in fuel cells
• Study of the electrochemical properties of 2D materials and their applications in energy storage and conversion devices
• Development of efficient electrochemical systems for desalination and water treatment applications
• Investigation of the electrochemical properties of metal-oxide nanoparticles for energy storage and conversion applications
• Analysis of the electrochemical behavior of redox-active organic molecules and their application in energy storage and conversion devices
• Study of the electrochemical behavior of metal-organic frameworks (MOFs) for the catalytic conversion of CO2 to value-added chemicals
• Development of novel electrode materials for electrochemical capacitors with high energy density and fast charge/discharge rates
• Investigation of the electrochemical properties of perovskite materials for energy storage and conversion applications
• Study of the electrochemical behavior of enzymes and their application in bioelectrochemical systems
• Development of advanced electrochemical techniques for the characterization of interfacial processes in electrochemical systems
• Analysis of the electrochemical behavior of nanocarbons and their application in electrochemical energy storage devices
• Investigation of the electrochemical properties of ionic liquids for energy storage and conversion applications.

Surface Chemistry Research Topics

Surface Chemistry Research Topics are as follows:

• Surface modification of nanoparticles for enhanced catalytic activity
• Investigating the effect of surface roughness on the wetting behavior of materials
• Development of new materials for solar cell applications through surface chemistry techniques
• Surface chemistry of graphene and its applications in electronic devices
• Surface functionalization of biomaterials for biomedical applications
• Characterization of surface defects and their effect on material properties
• Surface modification of carbon nanotubes for energy storage applications
• Developing surface coatings for corrosion protection of metals
• Synthesis of self-assembled monolayers on surfaces for sensor applications
• Surface chemistry of metal-organic frameworks for gas storage and separation
• Investigating the role of surface charge in protein adsorption
• Developing surfaces with superhydrophobic or superoleophobic properties for self-cleaning applications
• Surface functionalization of nanoparticles for drug delivery applications
• Surface chemistry of semiconductors and its effect on photovoltaic properties
• Development of surface-enhanced Raman scattering (SERS) substrates for trace analyte detection
• Surface functionalization of graphene oxide for water purification applications
• Investigating the role of surface tension in emulsion formation and stabilization
• Surface modification of membranes for water desalination and purification
• Synthesis and characterization of metal nanoparticles for catalytic applications
• Development of surfaces with controlled wettability for microfluidic applications.

Atmospheric Chemistry Research Topics

Atmospheric Chemistry Research Topics are as follows:

• The impact of wildfires on atmospheric chemistry
• The role of aerosols in atmospheric chemistry
• The chemistry and physics of ozone depletion in the stratosphere
• The chemistry and dynamics of the upper atmosphere
• The impact of anthropogenic emissions on atmospheric chemistry
• The role of clouds in atmospheric chemistry
• The chemistry of atmospheric particulate matter
• The impact of nitrogen oxides on atmospheric chemistry and air quality
• The effects of climate change on atmospheric chemistry
• The impact of atmospheric chemistry on climate change
• The chemistry and physics of atmospheric mercury cycling
• The impact of volcanic eruptions on atmospheric chemistry
• The chemistry and physics of acid rain formation and effects
• The role of halogen chemistry in the atmosphere
• The chemistry of atmospheric radicals and their impact on air quality and health
• The impact of urbanization on atmospheric chemistry
• The chemistry and physics of stratospheric polar vortex dynamics
• The role of natural sources (e.g. ocean, plants) in atmospheric chemistry
• The impact of atmospheric chemistry on the biosphere
• The chemistry and dynamics of the ozone hole over Antarctica.

Photochemistry Research Topics

Photochemistry Research Topics are as follows:

• Investigating the mechanisms of photoinduced electron transfer reactions in organic photovoltaic materials.
• Developing novel photoredox catalysts for photochemical reactions.
• Understanding the effects of light on DNA and RNA stability and replication.
• Studying the photochemistry of atmospheric pollutants and their impact on air quality.
• Designing new photoresponsive materials for advanced photonic and electronic devices.
• Exploring the photochemistry of metalloporphyrins for potential applications in catalysis.
• Investigating the photochemistry of transition metal complexes and their use as photodynamic therapy agents.
• Developing new photocatalytic systems for sustainable energy production.
• Studying the photochemistry of natural products and their potential pharmaceutical applications.
• Investigating the role of light in the formation and degradation of environmental contaminants.
• Designing new photochromic materials for smart windows and displays.
• Exploring the photochemistry of carbon nanomaterials for energy storage and conversion.
• Developing new light-driven molecular machines for nanotechnology applications.
• Investigating the photochemistry of organic dyes for potential applications in dye-sensitized solar cells.
• Studying the effects of light on the behavior of biological macromolecules.
• Designing new photoresponsive hydrogels for drug delivery applications.
• Exploring the photochemistry of semiconductor nanoparticles for potential applications in quantum computing.
• Investigating the mechanisms of photochemical reactions in ionic liquids.
• Developing new photonic sensors for chemical and biological detection.
• Studying the photochemistry of transition metal complexes for potential applications in water splitting and hydrogen production.

About the author

Muhammad Hassan

Researcher, Academic Writer, Web developer

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Collection  29 March 2022

2021 Top 25 Chemistry and Materials Sciences Articles

We are pleased to share with you the 25 most downloaded  Nature Communications  articles* in chemistry and materials sciences published in 2021. Featuring authors from around the world, these papers highlight valuable research from an international community.

Browse all Top 25 subject area collections  here .

*Data obtained from SN Insights (based on Digital Science's Dimensions) and normalised to account for articles published later in the year.

Research highlights

Mechanochemical synthesis of magnesium-based carbon nucleophiles in air and their use in organic synthesis

Grignard reagents have widespread utility in organic chemistry, but their preparation is limited by several drawbacks, such as the use of dry organic solvents and long reaction times. Here, the authors report a general mechanochemical synthesis of Grignard reagents in paste form in air, using a ball milling technique.

• Rina Takahashi

Programmable microbial ink for 3D printing of living materials produced from genetically engineered protein nanofibers

Living cells can precisely assemble to build 3D functional architectures. Here the authors produce an extrudable microbial ink entirely from the engineered cells, which can be further programmed to 3D print functional living materials.

• Anna M. Duraj-Thatte
• Avinash Manjula-Basavanna
• Neel S. Joshi

A novel mechanism for the loss of mRNA activity in lipid nanoparticle delivery systems

Lipid nanoparticle delivery of mRNA vaccines has become of particular importance, however, mRNA stability is a major concern. Here, the authors report on a study of lipid impurity mRNA interactions using reverse phase ion pair HPLC to identify reactions which render the mRNA untranslatable, reducing vaccine efficiency.

• Meredith Packer
• Dipendra Gyawali

Understanding Li-based battery materials via electrochemical impedance spectroscopy

Electrochemical impedance spectroscopy is a key technique for understanding Li-based battery processes. Here, the authors discuss the current state of the art, advantages and challenges of this technique, also giving an outlook for future developments.

• Miran Gaberšček

A general strategy for C(sp 3 )–H functionalization with nucleophiles using methyl radical as a hydrogen atom abstractor

When carbon-based units are functionalized in photoredox catalysis, electrophilic coupling partners are often used, such that the polarities of the two fragments are appropriately matched. Here the authors show a generalized methodology to instead use nucleophilic coupling partners, which are cheaper and often simpler, via successive hydrogen atom transfer and oxidative radical-polar crossover.

• Isabelle Nathalie-Marie Leibler
• Makeda A. Tekle-Smith
• Abigail G. Doyle

Identifying molecules as biosignatures with assembly theory and mass spectrometry

The search for life in the universe is difficult due to issues with defining signatures of living systems. Here, the authors present an approach based on the molecular assembly number and tandem mass spectrometry that allows identification of molecules produced by biological systems, and use it to identify biosignatures from a range of samples, including ones from outer space.

• Stuart M. Marshall
• Cole Mathis
• Leroy Cronin

Tempering of cocoa butter and chocolate using minor lipidic components

In chocolate production, a complicated tempering process is used to guide the crystallization of cocoa butter towards its most desirable polymorph, which gives the chocolate proper melting behavior, gloss, and snap—hallmarks of good quality chocolate. Here, the authors find that simply adding a specific phospholipid also directs crystallization towards this polymorph, producing chocolate with comparable microstructure and properties to tempered chocolate.

• Saeed M. Ghazani
• Alejandro G. Marangoni

Production of high-energy Li-ion batteries comprising silicon-containing anodes and insertion-type cathodes

Large-scale manufacturing of high-energy Li-ion cells is of paramount importance for developing efficient rechargeable battery systems. Here, the authors report in-depth discussions and evaluations on the use of silicon-containing anodes together with insertion-based cathodes.

• Gebrekidan Gebresilassie Eshetu
• Egbert Figgemeier

Proliferating coacervate droplets as the missing link between chemistry and biology in the origins of life

Coacervate droplets (CDs) are a model for protocells formed by liquid-liquid phase separation (LLPS), but protocell models able to proliferate remain undeveloped. Here, the authors report a proliferating peptide-based CD using synthesised amino acid thioesters as monomers, which could concentrate RNA and lipids, enabling RNA to protect the droplet from dissolution by lipids.

• Muneyuki Matsuo
• Kensuke Kurihara

Nickel-catalyzed electrochemical carboxylation of unactivated aryl and alkyl halides with CO 2

Electrochemistry is a promising approach to make existing chemical protocols milder, but many simple transformations of feedstocks are still out of reach. Here, the authors transform unactivated aryl and alkyl (pseudo)halides into carboxylic acids, via nickel catalysis and electricity, using atmospheric CO 2 as the carbon source.

• Guo-Quan Sun

Gene editing enables rapid engineering of complex antibiotic assembly lines

Engineering biosynthetic assembly lines is a powerful path to new natural products but is challenging with current methods. Here the authors use CRISPR-Cas9 to exchange subdomains within NRPS to alter substrate selectivity.

• Wei Li Thong
• Yingxin Zhang
• Jason Micklefield

Electrochemical ammonia synthesis via nitrate reduction on Fe single atom catalyst

Developing green and delocalized routes for ammonia synthesis is highly important but still very challenging. Here the authors report an efficient ammonia synthesis process via nitrate reduction to ammonia on Fe single atom catalyst.

• Mohammadreza Karamad
• Haotian Wang

Coordination environment dependent selectivity of single-site-Cu enriched crystalline porous catalysts in CO 2 reduction to CH 4

Crystalline porous catalysts with single Cu sites are dedicated to exploring the dependence of CO 2 electroreduction selectivity on the coordination environment of catalytic sites. The conductive MOF Cu-DBC with oxygen-coordinated Cu sites shows a high Faradaic efficiency ~80% of CO 2 -to-CH 4 .

• Long-Zhang Dong
• Ya-Qian Lan

6 nm super-resolution optical transmission and scattering spectroscopic imaging of carbon nanotubes using a nanometer-scale white light source

The authors present a super-resolution hyperspectral imaging technique using a nanoscale white light source generated by superfocusing light from a tungsten-halogen lamp. They achieve 6 nm resolution, measuring longitudinal and transverse optical electronic transitions in single-walled carbon nanotubes.

Electrochemical C–N bond activation for deaminative reductive coupling of Katritzky salts

Electrochemical transformations use electrons and electron holes instead of chemical oxidants and reductants as reagents. Here, the authors report an electrochemical reductive deaminative cross-coupling of Katrizky salts with various radical acceptors, including examples of fluoroalkenylation, alkynylation and thiolation.

• Xiangzhang Tao

Ultra-thin self-healing vitrimer coatings for durable hydrophobicity

By now a plethora of ultrathin hydrophobic coatings are available but their durability are not well developed. Here, the authors present a thin, durable and fluorine-free PDMS-based vitrimer coating that implements many desirable aspects like energy efficiency, durability and sustainability.

• Jingcheng Ma
• Laura E. Porath
• Christopher M. Evans

A saccharide-based binder for efficient polysulfide regulations in Li-S batteries

The long-term cycling of Li-S batteries depends on the polysulfides shuttling regulation. Here, the authors present a saccharide-based binder system to control the polysulfides migration and improve the cycle life of a Li-S pouch cell.

• Yingyi Huang
• Mahdokht Shaibani
• Mainak Majumder

Sustained enzymatic activity and flow in crowded protein droplets

Living cells can harvest environmental energy to drive chemical processes. Here the authors design a minimal artificial system that achieves steady states at similar metabolic densities to microorganisms.

• Andrea Testa
• Mirco Dindo
• Paola Laurino

Freezing of few nanometers water droplets

Ice nucleation in confined geometries is a ubiquitous phenomenon, but difficult to characterize. Here the authors investigate experimentally the freezing of water nanodroplets surrounded by octane in nanopores down to 2 nm, and demonstrate that the soft curved oil-water interface suppresses heterogeneous ice nucleation, which occurs at a lower temperature than homogenous bulk nucleation.

• Alireza Hakimian
• Mohammadjavad Mohebinia
• Hadi Ghasemi

Transition metal-doped Ni-rich layered cathode materials for durable Li-ion batteries

Long-term efficient cycling stability is of paramount importance for the development of high-energy Li-ion batteries. Here, the authors investigate the effect of transition metal dopants on the electrochemical, morphological, and structural properties of Ni-rich cathode active materials.

• H. Hohyun Sun
• Un-Hyuck Kim
• Yang-Kook Sun

Divergent functionalization of aldehydes photocatalyzed by neutral eosin Y with sulfone reagents

Acyl radicals represent a reactive species that allow for aldehyde subunits to be nucleophilic instead of their typical electrophilic behavior; however, these species are difficult to access in mild conditions. Here the authors show a method to generate acyl radicals using only an organic photocatalyst and light, and these species are shown as competent nucleophiles in a variety of couplings.

• Jianming Yan

Engineering single-atomic ruthenium catalytic sites on defective nickel-iron layered double hydroxide for overall water splitting

Rational design of single atom catalyst is critical for efficient sustainable energy conversion. Single-atomic-site ruthenium stabilized on defective nickel-iron layered double hydroxide nanosheets achieve superior HER and OER performance in alkaline media.

• Panlong Zhai
• Mingyue Xia
• Jungang Hou

Artificial intelligence-enhanced quantum chemical method with broad applicability

Artificial intelligence is combined with quantum mechanics to break the limitations of traditional methods and create a new general-purpose method for computational chemistry simulations with high accuracy, speed and transferability.

• Peikun Zheng
• Roman Zubatyuk
• Pavlo O. Dral

Controlled self-assembly of plant proteins into high-performance multifunctional nanostructured films

Green use of plant derived proteins in functional materials has been limited by inefficient methods to control micro and nanoscale structure. Here, the authors use nanoscale assembly of water-insoluble plant proteins to make meter scale films with comparable properties to conventional plastics.

• Ayaka Kamada
• Marc Rodriguez-Garcia
• Tuomas P. J. Knowles

Moving beyond bimetallic-alloy to single-atom dimer atomic-interface for all-pH hydrogen evolution

While single, dispersed atoms enable efficient atomic utilization, controllably preparing single-atom dimers remains challenging. Here, authors prepare nickel-cobalt single-atom dimers as high-performance pH-universal H 2 evolution electrocatalysts.

• Ashwani Kumar
• Viet Q. Bui
• Hyoyoung Lee

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[100+] Organic Chemistry Research Topics For College Students With Free [Thesis Pdf]

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100+ Great Chemistry Research Topics

Table of contents

• 1 What are the best chemistry research topics?
• 2 5 Tips for Writing Chemistry Research Papers
• 3 Chemical Engineering Research Topics
• 4 Organic Сhemistry Research Topics
• 5 Іnorganic Сhemistry Research Topics
• 6 Biomolecular Сhemistry Research Topics
• 7 Analytical Chemistry Research Topics
• 8 Computational Chemistry Research Topics
• 9 Physical Chemistry Research Topics
• 10 Innovative Chemistry Research Topics
• 11 Environmental Chemistry Research Topics
• 12 Green Chemistry Research Topics
• 13.1 Conclusion

Do you need a topic for your chemistry research paper? Are you unsure of where to start? Don’t worry – we’re here to help. In this post, we’ll go over a series of the best chemistry research paper topics as well as Tips for Writing Chemistry Research Papers on different topics. By the time you finish reading this post, you’ll have plenty of ideas to get started on your next research project!

There are many different subfields of chemistry, so it can be tough to find interesting chemistry topics to write about. If you’re struggling to narrow down your topic, we’ll go over lists of topics in multiple fields of study.

What are the best chemistry research topics?

Doing research is important to help scientists learn more about the world around us. By researching different compounds and elements, we can learn more about how they interact with one another and how they can be used to create new products or improve existing ones.

There are many different topics that you can choose to research in chemistry. Here are just a few examples:

• The history of chemistry and how it has evolved over time
• How different chemicals react with one another
• How to create new compounds or improve existing ones
• The role of chemistry in the environment
• The health effects of different chemicals

5 Tips for Writing Chemistry Research Papers

Once you have chosen a topic for your research paper , it is important to follow some tips to ensure that your paper is well-written and accurate. Here are a few tips to get you started:

• Start by doing some background research on your topic. This will help you understand the basics of the topic and give you a good foundation to build your paper on.
• Make sure to cite all of the sources that you use in your paper. This will help to show where you got your information and will also help to add credibility to your work.
• Be sure to proofread your paper before you submit it. This will ensure that there are no errors and that your paper is clear and concise.
• Get help from a tutor or friend if you are struggling with your paper. They may be able to offer helpful advice or feedback.
• Take your time when writing your research paper . This is not a race, and it is important to make sure that you do a good job on your research.

By following these tips, you can be sure that your chemistry research paper will be a success! So what are you waiting for? Let’s go over some of the best research paper topics out there.

Chemical Engineering Research Topics

Chemical Engineering is a branch of engineering that deals with the design and application of chemical processes. If you’re wondering how to choose a paper topic, here are some ideas to inspire you:

• How to create new alloy compounds or improve existing ones
• The health effects of the food industry chemicals
• Chemical engineering and sustainable development
• The future of chemical engineering
• Chemical engineering and the food industry
• Chemical engineering and the pharmaceutical industry
• Chemical engineering and the cosmetics industry
• Chemical engineering and the petrochemical industry

These are just a few examples – there are many more possibilities out there! So get started on your research today. Who knows what you might discover!

Organic Сhemistry Research Topics

Organic chemistry is the study of carbon-containing molecules. There are many different organic chemistry research topics that a student could choose to focus on and here are just a few examples of possible research projects in organic chemistry:

• Investigating new methods for synthesizing chiral molecules
• Studying the structure and reactivity of carbon nanotubes
• Investigating metal complexes with organometallic ligands
• Designing benzene derivatives with improved thermal stability
• Exploring new ways to control the stereochemistry of chemical reactions
• Studying the role of enzymes in organic synthesis
• Investigating new strategies for combating drug resistance
• Developing new methods for detecting explosives residues
• Studying the photochemistry of organic molecules
• Studying the behavior of organometallic compounds in biological systems

Іnorganic Сhemistry Research Topics

Inorganic Chemistry is the study of the chemistry of materials that do not contain carbon. Unlike other chemistry research topics, these include elements such as metals, minerals, and inorganic compounds. If you are looking for inorganic chemistry research topics on inorganic chemistry, here are some ideas to get you started:

• How different metals react with one another
• How to create new alloys or improve existing ones
• The role of inorganic chemistry in the environment
• Inorganic chemistry and sustainable development
• The future of inorganic chemistry
• Inorganic chemistry and the food industry
• Inorganic chemistry and the pharmaceutical industry
• Atomic structure progressive scale grading
• Inorganiс Сhemistry and the cosmetics industry

Biomolecular Сhemistry Research Topics

Biomolecular chemistry is the study of molecules that are important for life. These molecules can be found in all living things, from tiny bacteria to the largest animals. Researchers who work in this field use a variety of techniques to learn more about how these molecules function and how they interact with each other.

If you are looking for essential biomolecular chemistry research topics, here are some ideas to get you started:

• The structure and function of DNA
• The structure and function of proteins
• The role of carbohydrates in the body
• The role of lipids in the body
• How enzymes work
• The role of biochemistry in heart disease
• Cyanides and their effect on the body
• The role of biochemistry in cancer treatment
• The role of biochemistry in Parkison’s disease treatment
• The role of biochemistry in the immune system

The possibilities are endless for someone willing to dedicate some time to research.

Analytical Chemistry Research Topics

Analytical Chemistry is a type of chemistry that helps scientists figure out what something is made of. This can be done through a variety of methods, such as spectroscopy or chromatography. If you are looking for research topics, here are some ideas to get you started:

• How food chemicals react with one another
• Mass spectrometry
• Analytical aspects of gas and liquid chromatography
• Analytical chemistry and sustainable development
• Atomic absorption spectroscopy methods and best practices
• Analytical chemistry and the pharmaceutical industry in Ibuprofen consumption
• Analytical chemistry and the cosmetics industry in UV protectors
• Dispersive x-ray analysis of damaged tissues

Analytical chemistry is considered by many a complex science and there is a lot yet to be discovered in the field.

Computational Chemistry Research Topics

Computational chemistry is a way to use computers to help chemists understand chemical reactions. This can be done by simulating reactions or by designing new molecules. If you are looking for essential chemistry research topics in computational chemistry, here are some ideas to get you started:

• Molecular mechanics simulation
• Reaction rates of complex chemical reactions
• Designing new molecules: how can simulation help
• The role of computers in the study of quantum mechanics
• How to use computers to predict chemical reactions
• Using computers to understand organic chemistry
• The future of computational chemistry in organic reactions
• The impacts of simulation on the development of new medications
• Combustion reaction simulation impact on engine development
• Quantum-chemistry simulation review

Computers are cutting-edge technology in chemical research and this relatively new field of study has a ton yet to be explored.

Physical Chemistry Research Topics

Physical chemistry is the study of how matter behaves. It looks at the physical and chemical properties of atoms and molecules and how they interact with each other. If you are looking for physical chemistry research topics, here are some ideas to get you started:

• Standardization of pH scales
• Structure of atom on a quantum scale
• Bonding across atoms and molecules
• The effect of temperature on chemical reactions
• The role of light in in-body chemical reactions
• Chemical kinetics
• Surface tension and its effects on mixtures
• The role of pressure in chemical reactions
• Rates of diffusion in gases and liquids
• The role of entropy in chemical reactions

Here are just a few samples, but there are plenty more options! Start your research right now!

Innovative Chemistry Research Topics

Innovative chemistry is all about coming up with new ideas and ways to do things. This can be anything from creating new materials to finding new ways to make existing products. If you are looking for ground-breaking chemistry research topics, here are some ideas to get you started:

• Amino acids side chain effects in protein folding
• Chemistry in the production of nanomaterials
• The role of enzymes in chemical reactions
• Photocatalysis in 3D printing
• Avoiding pesticides in agriculture
• Combining chemical and biological processes
• Gene modification in medicinal chemistry
• The role of quantum mechanics in chemical reactions
• Astrochemical research on extraterrestrial molecules
• Spectroscopy signatures of pressurized organic components

If you need a hand, there are several sites that also offer research papers for sale and can be a great asset as you work to create your own research papers.

Whatever route you decide to take, good luck! And remember – the sky’s the limit when it comes to research! So get started today and see where your studies may take you. Who knows, you might just make a breakthrough discovery!

Environmental Chemistry Research Topics

Environmental Chemistry is the study of how chemicals interact with the environment. This can include anything from the air we breathe to the water we drink. If you are looking for environmental chemistry research topics, here are some ideas to get you started:

• Plastic effects on ocean life
• Urban ecology
• The role of carbon in climate change
• Air pollution and its effects
• Water pollution and its effects
• Chemicals in food and their effect on the body
• The effect of chemicals on plant life
• Earth temperature prediction models

A lot of research on the environment is being conducted at the moment because the environment is in danger. There are a lot of environmental problems that need to be solved, and research is the key to solving them.

Green Chemistry Research Topics

Green chemistry is the study of how to make products and processes that are environmentally friendly. This can include anything from finding new ways to recycle materials to developing new products that are biodegradable. If you are looking for green chemistry research topics, here are some ideas to get you started:

• Recycling and reuse of materials
• Developing biodegradable materials
• Improving existing recycling processes
• Green chemistry and sustainable development
• The future of green chemistry
• Green chemistry and the food industry
• Green chemistry and the pharmaceutical industry
• Green chemistry and the cosmetics industry

A more environmentally friendly world is something we all aspire for and a lot of research has been conducted on how we can achieve this, making this one of the most promising areas of study. The results have been varied, but there are a few key things we can do to make a difference.

Controversial Chemistry Research Topics

Controversial chemistry is all about hot-button topics that people are passionate about. This can include anything from the use of chemicals in warfare to the health effects of different chemicals. If you are looking for controversial topics to write about , here are some ideas to get you started:

• The use of chemicals in warfare
• Gene modification in human babies
• Bioengineering
• How fast food chemicals affect the human brain
• The role of the government in regulating chemicals
• Evolution of cigarette chemicals over time
• Chemical effects of CBD oils
• Antidepressant chemical reactions
• Synthetic molecules replication methods
• Gene analysis

Controversial research papers often appear in the media before it has been peer-reviewed and published in a scientific journal. The reason for this is that the media is interested in stories that are new, exciting, and generate a lot of debate.

Chemistry is an incredibly diverse and interesting field, with many controversial topics to write about. If you are looking for a research topic, consider the examples listed in this article. With a little bit of effort, you are sure to find a topic that is both interesting and within your skillset.

In order to be a good researcher, it is important to be able to think critically and solve problems. However, innovation in chemistry research can be challenging. When thinking about how to innovate, it is important to consider both the practical and theoretical aspects of your research. Additionally, try to build on the work of others in order to create something new and unique. With a little bit of effort, you are sure to be able to find a topic that is both interesting and within your skillset.

Happy writing!

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• ACS Publications

Hot Topics in Chemistry at ACS Spring 2024: Part 1

• Mar 18, 2024

From edible bugs to exercise in pill form, we bring you a roundup of hot topics and breakthrough chemistry research presented at ACS Spring 2024.

The spring meeting of the American Chemical Society (ACS), held virtually and in person March 17-21, 2024, features more than 12,000 presentations on a diverse range of science topics. Read on to discover some of the hot topics and research highlights* presented at the meeting—and check back throughout the week for more updates!

1. Seasonal Secrets Unveiled: How Wild Animals' Hair Changes to Beat the Cold

Learn how wild animals have evolved to survive extreme temperatures in the groundbreaking research led by Taylor Millett at Utah Tech University. This study explores the fascinating world of animal hair, revealing for the first time that the inner structure of animals' coats undergoes significant changes with the seasons. Unlike common beliefs that only the color of the hair changes, Millett's research shows microscopic alterations within the hair that are crucial for survival in different weather conditions.

Millett and her colleagues explored the complex hair structures of wild, big-game animals including the pronghorn antelope, mule deer, and Rocky Mountain elk. Using advanced scanning electron microscopy, they discovered the unique 'honeycomb' structure within the hairs, which changes in density and size between seasons to provide essential insulation. Their findings not only shed light on nature's ingenious ways of protecting these animals but also suggest possibilities for other applications, such as synthetic insulation for homes and consumer products.

2. Bugging Out: The Surprisingly Tasty World of Edible Ants

When it comes to keeping with ACS Spring 2024's theme of " Many Flavors of Chemistry ," Changqi Liu and his colleagues understood the assignment. Their latest research uncovers the diverse and rich flavor profiles of edible ants , diving deep into the unique aroma profiles of four distinct ant species. From the acidic and vinegary taste of common black ants to the nutty and woody nuances of chicatana ants, their findings reveal that each species brings its own unique set of tastes and smells to the table, advancing our understanding of these insects' culinary potential.

The study also touches on the potential for incorporating these flavors into new food products, particularly as the world seeks more sustainable and eco-friendly protein alternatives.

Watch the Headline Science video surrounding this research, created by the ACS Science Communications team:

Explore More Bug Science on ACS Axial

Worm Slime: The Key to More Eco-Friendly Plastics? The Secret of Spinning A Bug’s Eye View of Road Safety

3. A Chemist's Guide to Brewing Perfect Kombucha

A team of chemists at Shippensburg University are revolutionizing kombucha brewing , tackling the challenges of inconsistent alcohol levels and flavor profiles in the fermented beverage. Their research reports on innovative ways to control alcohol content, enhance taste, and speed up fermentation, offering new insights for both home and commercial kombucha producers.

First, the team analyzed the fermentation process in different containers, where silicone bags showed superior performance over glass jars in both fermentation speed and increased acid production. They also looked into how different sugars affect kombucha's taste and alcohol content. Using glucose as a starter resulted in higher gluconic acid and lower ethanol levels, while fructose led to sweeter brews with more acetic acid and ethanol. These findings are crucial for brewers aiming to tailor their kombucha to specific flavor profiles and alcohol content.

This is not the team's first foray into the art and science of kombucha brewing. In 2023, they published a study in the Journal of Chemical Education exploring the use of a cost-effective sensor to accurately measure alcohol concentrations in kombucha across a variety of undergraduate chem lab courses. Read the article here .

Watch the Headline Science short surrounding this research, created by the ACS Science Communications team:

Read More Booze & Beverage Chemistry on Axial:

What Gives Red Bordeaux Wine a “Meaty” Aroma? Beyond the Bean: The Science Behind Lab-Grown Coffee Staying Fresh: The Chemistry of Beer Packaging Like a Fine (Sparkling) Wine: How to Age Champagne Without Losing the Bubbles

4. A New Decking Material That Fights Global Warming

In a major stride towards environmentally sustainable construction, David Heldebrant and his team have developed a new composite decking material that is both cheaper than standard options and carbon-negative. It's designed to store more carbon dioxide (CO 2 ) than its manufacturing process emits, providing a viable solution to one of the construction sector's most significant challenges: high carbon emissions.

The new material incorporates low-quality brown coal and lignin as fillers, which are then treated with CO 2 . Not only does this composite meet international building codes for decking materials in terms of strength and durability, but it also offers a significant cost advantage, being 18% cheaper than its conventional counterparts.

This type of composite decking could play a pivotal role in reducing the carbon footprint of the building industry: replacing all U.S. decking with this material could sequester the CO 2 equivalent of the annual emissions from 54,000 cars. As the team works towards commercialization, this carbon-negative decking presents a hopeful glimpse into a more sustainable solution for the construction industry.

Read more of David Hildebrant's research on CO 2 capture published in ACS journals:

Water-Lean Solvents for Post-Combustion CO 2 Capture: Fundamentals, Uncertainties, Opportunities, and Outlook David J. Heldebrant*Orcid, Phillip K. KoechOrcid, Vassiliki-Alexandra GlezakouOrcid, Roger RousseauOrcid, Deepika Malhotra, and David C. Cantu DOI : 10.1021/acs.chemrev.6b00768

In Situ Raman Methodology for Online Analysis of CO 2 and H 2 O Loadings in a Water-Lean Solvent for CO 2 Capture Amanda M. Lines, Dushyant Barpaga*, Richard F. Zheng, James R. Collett, David J. Heldebrant, and Samuel A. Bryan* DOI : 10.1021/acs.analchem.3c02281

Directed Hydrogen Bond Placement: Low Viscosity Amine Solvents for CO2 Capture Deepika Malhotra, David C. Cantu, Phillip K. Koech*, David J. Heldebrant, Abhijeet Karkamkar, Feng Zheng, Mark D. Bearden, Roger Rousseau, and Vassiliki-Alexandra Glezakou* DOI : 10.1021/acssuschemeng.8b05481

5. A Pill to Replace the Gym?

While this may seem too good to be true, researchers have recently identified new compounds that can mimic the physical benefits of exercise—a significant advancement particularly for those unable to engage in regular physical activity.

The team, led by Bahaa Elgendy at Washington University School of Medicine, initially developed SLU-PP-332 , a compound that activates estrogen-related receptors (ERRs), which are crucial in muscle adaptation to exercise. While SLU-PP-332 was a pioneering discovery, it had its limitations—particularly in its inability to cross into the brain.

To improve upon SLU-PP-332, the team engineered new molecules that not only demonstrated a stronger activation of the ERRs but also exhibited attributes like enhanced stability and lower toxicity potential. Their effectiveness was measured through an increase in RNA presence in rat heart muscle cells, suggesting a more robust simulation of exercise effects compared to SLU-PP-332.

A crucial advancement with the new compounds is their ability to penetrate the brain, opening possibilities for treating neurodegenerative disorders like Alzheimer's disease. Elgendy and his team hope to further test these compounds in animal models, potentially leading to new treatments for various medical conditions where exercise-mimicking drugs could be beneficial.

Read more of Bahaa Elgendy's research published in ACS journals:

Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity Cyrielle Billon, Sadichha Sitaula, Subhashis Banerjee, Ryan Welch, Bahaa Elgendy, Lamees Hegazy, Tae Gyu Oh, Melissa Kazantzis, Arindam Chatterjee, John Chrivia, Matthew E. Hayes, Weiyi Xu, Angelica Hamilton, Janice M. Huss, Lilei Zhang, John K. Walker, Michael Downes, Ronald M. Evans, and Thomas P. Burris* DOI : 10.1021/acschembio.2c00720

Synthesis of 3-Aminoquinazolinones via a SnCl 2 -Mediated ANRORC-like Reductive Rearrangement of 1,3,4-Oxadiazoles Mohamed Elagawany, Lingaiah Maram, and Bahaa Elgendy* DOI : 10.1021/acs.joc.3c01973

Recent Advances in the Medicinal Chemistry of Farnesoid X Receptor Yuanying Fang, Lamees Hegazy, Brian N. Finck, and Bahaa Elgendy* DOI : 10.1021/acs.jmedchem.1c01017

6. Revolutionizing Cancer Research with Artificial Mucus

Led by Jessica Kramer at the University of Utah, this study marks a significant advancement in understanding the role of mucus in tumor formation. By synthesizing mucins, the sugar-coated proteins that mucus primarily consists of, the team discovered that altering the mucins in healthy cells to resemble those in cancer cells can induce cancer-like behaviors in these cells.

Kramer's approach, involving synthetic chemistry and bacterial enzymes, allows for the precise alteration of mucins and reveals how specific changes in their sugar or protein sequences can impact cellular behavior. This methodology led to the observation that healthy epithelial cells with modified, cancer-like mucins cease normal cell extrusion and begin to pile up, a process resembling early tumor formation. While it's still unclear if these cells transform into cancer cells, the findings open new avenues for developing cancer treatments targeting mucins, particularly the sugar groups on these molecules. Beyond cancer, this research could lead to the development of anti-infectives, probiotics, and other health-supporting therapies.

*Press Release content and videos in this post are brought to you by the ACS Science Communications team. Learn more below.

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232 Chemistry Research Topics To Make Your Neurochemicals Dance

Speaking from experience, science can be fun. The only thing that matters is that you should always choose the theme/field that fascinates you the most. Chemistry, if done right, can give you more dopamine rush than riding a racing bike. The trick is to choose a chemistry research paper topic that moves your quarks when you’re writing about it. 

Table of Contents

Chemistry Research Topics: Biochemistry, Chemical, Organic, and more

Our chemistry research writers are not regular researchers but people who actually study and love chemistry. They have spent a lot of time unearthing some of the cool topics that could pump any chemistry geeks with an adrenaline rush. They have years of experience offering chemistry research paper writing services, so you can trust their work.  (Many people around the world already do and you can find that in testimonials on our  PhD Research Paper Writing Services  page.)

Physical chemistry research topics

• Laws of Thermodynamics
• Energy Balance
• Gases: Gas Law
• harles and Gay Lussac’s law
• General Ideal Gas Law
• The mass of a chemical compound
• The moles of an atomic species
• The flow of Fluids in Closed Ducts
• Impact of gravity on the fluids
• Strength effect of elasticity of fluid actions
• Surface tension in fluids
• Statistical Analysis Of Thermodynamic Properties
• Determination of the ideal gas constant
• pH determination
• Distillation of an azeotropic mixture
• Cubic equations of state
• Redox titrations
• Ideal solutions (liquids)
• Laboratory on the States of Matter
• Laboratory on the construction of an atom
• Research on molecular geometry
• Research on the density of bodies
• Kinetic studies of pyrolysis, combustion and gasification of various materials (organic and inorganic)
• Physicochemical Processes of Interaction of Metals with Biomaterials
• Photochemistry of Compounds of Environmental Interest
• Study of the kinetic, thermodynamic and catalytic activity of compounds
• Organic and inorganic academic and environmental interest
• Determination of heat of combustion of acetamidophenols
• Experimental determination of thermochemical properties of chemical compounds
• Experimental evaluation of thermal properties of dangerous organic liquids
• Synthesis and characterization of hydrogels based on acrylic acid
• Incorporation of salts and other chemical substances in acrylic acid/acrylamide hydrogels
• Physical chemistry of polymers and macromolecules
• Pharmaceutical physical chemistry
• Physical chemistry and material sciences
• Biomimetic chemistry
• Petrochemical and related sciences
• Physical chemistry of semiconductors
• Physical chemistry of extractive processes
• Physical chemistry of surfaces

We bet these chemistry essay topics have blown you away. Don’t worry we have more useful topics coming your way.

Read More:  Accounting Research Topics

Electrochemistry research topics

Below are some of the best topics for research paper about chemistry and its affiliate subjects. Check them out:

• Calibration of carbon paste electrodes modified with iron particles
• Effect of ionic strength on electrochemical detection
• Oxygenated groups present in graphite powder
• Electrochemical analysis
• Potentiometric titrations of functional groups
• Physical and chemical characterization of the modified and unmodified material 
• Electrochemical recovery of toxic metals
• Carbon paste electrodes
• Biological and bioelectrochemical reactors with an optimization approach based on computational methods
• Electrogeneration of oxidizing species
• Electroremediation of contaminated water and water soils
• Electrochemistry: Importance in Robotics and Nanotechnology
• Electrochemistry in Ecology and Environmental Processes
• How electrochemistry plays an important role in energy generation
• Photovoltaic cells and hybrid energy systems
• Nanostructured materials for fuel cells
• Solar Systems and Electrochemistry
• Biomolecular interactions and electroanalysis
• Chemical and electrochemical methods in disease diagnosis
• Synthesis and Electrochemical Properties of Hexacyanoferrate-Doped Polypyrrole
• Energy Storage in Hybrid Organic-Inorganic Materials
• Conducting Organic Polymers with Electroactive Dopants
• Electrochemistry for bioprocess engineering applications
• Electrochemical enhancement of microbial product formation
• Electron transfer of electrode-bound enzymes
• Transport mechanism and interfacial reactions within the oxide layer
• Oxide layer modelling
• Preparative electrochemistry or electrosynthesis
• Electrochemical methods in analytical chemistry
• Electrochemical synthesis methods
• Fuel cell technology in Technical Chemistry 
• Electrochemical reactions
• Phase boundary electrode-electrolyte
• Phase boundary between an electronic conductor (electrode) and an ionic conductor (electrolyte)
• Applications of electrochemistry
• Reduction of metal salts for the production of base metals, mainly by electrolysis
• Use of electrolytic metal deposition in electroplating
• Provision of an electrical voltage, especially for mobile applications
• History of Electrochemistry

We know your chemistry research projects are incomplete without these eyecatching topics. Read them and wisely write on these subject to amaze your professor.

Read More:  Business Research Topics

Organic Chemistry research topics

• A novel process for the production of sophisticated molecules
• Addition of amino sugars to acetylenic compounds
• Environmental remediation and as a reaction containment medium
• Intermolecular interactions for the molecular recognition of peptides and proteins
• Synthesis of glycosylamines from disaccharides and lipooligosaccharides
• Catalysis with metal and organocatalysts, photocatalysis, natural product synthesis, unnatural amino acids and peptide foldamers
• Development and modification of gels based on polymers for use in drug delivery
• Reusable catalyst makes oxidation of CH bonds with oxygen easier and more efficient
• Structural analysis of nodulation factors produced by bacteria of the genus Rhizobium
• Imidazopyridines as new materials
• Effects of Ultra-Violet Light on Activation of Oxygen
• Synthesis of large unsymmetrical imines by a palladium-catalyzed cross-coupling reaction
• Improved pharmaceuticals thanks to fluorine
• Application of the hydroxy-ketone reductive grouping in obtaining trans-fused polyethers
• Role of Biochemistry in the creation of Antibiotics
• Application of the olefin metathesis (RCM) reaction in the synthesis of Orthocondensated polyoxepanes
• Sugars in green olives
• Synthetic applications of d-glucose derivatives
• Synthesis, structure, coordination and applications in asymmetric catalysis
• Natural product synthesis and convergent technologies
• Activation of growth factors for fibroblasts by glycosaminoglycans effect
• Thiols, preparation and handling
• Biotransformations of industrial interest catalyzed by fungal peroxygenases
• Carbohydrate multivalent systems functionalize proteins and surfaces
• Fused n-heterocyclic carbenes in biaryl systems
• Hair structure
• Biochemistry for bioremediation
• Chemical and structural characterization of lignin and lipids of lignocellulosic materials of industrial interest
• Physicochemical characterization of citronella, soapstone, and eucalyptus essential oil
• Electrophilic Substitution Reactions: Synthesis of Nitrobenzene
• Essential oils: uses and properties
• Activation of growth factors for fibroblasts by glycosaminoglycans

Read More:  Finance Research Topics

Inorganic Chemistry research topics

• Soil and water contamination by inorganic compounds
• Synthesis and characterization of Coordination Compounds and their use as homogeneous catalysts
• Free Radicals and Antioxidants
• Analytical Chemistry associated with the study of inorganic compounds
• Quantum molecular modeling and mechanics
• Inorganic Materials
• Hydrogen reactivity with inorganic compounds
• Bond theory analysis
• Chemistry of some transition elements
• Boric Acid Preparation
• Types of inorganic chemical reactions
• Introduction to inorganic chemistry
• Study of the atomic spectrum
• Crystal defects in inorganic chemistry
• Explosives and violent reactions in inorganic compounds
• Objective characterization of wines through aroma components
• Microstructural characterization of nanoparticles and magnetic “nano-composites” of iron
• Chemical, morphological, mineralogical, and genesis characters of the salt mines
• Physical and chemical characteristics of the soils occupied by olive groves
• Theoretical analysis and development of instrumentation to apply the new technique of thermal analysis at a constant rate of reaction
• Alteration of rocks and soil formation in Utah
• The catalytic activity of 4f metal oxides in the decomposition of various carboxylic acids and alcohols
• Activation of ethylene and carbon dioxide by molybdenum complexes
• Platinum promoting action on nickel catalysts supported on activated Bentonite
• Homogeneous catalysis (with an organometallic, transition metal, lanthanide and representative compounds)
• Methods of synthesis of organometallic compounds assisted by microwaves.
• Design of molecular precursors with relevance in materials chemistry.
• Chemistry of inorganic heterocycles.
• Immobilization of organometallic and coordination compounds in polypropylene membranes.

Read More: High School Research Topics

Biochemistry research topics

• Bioinformatics and Computational Biology
• Cell differentiation and metabolism
• Biochemistry of Individual Molecules
• Enterobacteriaceae envelopes: modulation of their structure in response to environmental cues and impact on pathogenicity
• Neuroplasticidad y Neurogenética
• Environmental biotechnology applied to water decontamination.
• Reproductive Aging
• Neurobiochemistry
• Regulatory proteins of iron metabolism
• Iron deficiency anaemia and cardiovascular disease
• Iron deficiency anaemia and oxidative stress
• Nutritional anaemias independent workers
• Food incompatibilities for iron absorption
• Evaluation of anaemia and iron deficiency in schoolchildren
• Iron deficiency anaemia and evaluation of school performance
• Iron deficiency anaemia in students of Educational Centers
• Copper Levels and Oxidative Stress in the Elderly
• Iron Levels and Oxidative Stress in the Elderly
• Evaluation of transcription factors (surgical samples)
• Biochemical markers in oxidative stress
• Antioxidant activity in irradiated food products
• Kinetics of the reactivity of antioxidants in food
• Evaluation of oxidative stress in various pathological states
• Iron levels in the Elderly
• Copper Levels in the Elderly
• Evaluation of the synergistic effect in a mixture of antioxidant compounds
• Antioxidant activity in medicinal plants
• Food patterns and evaluation of antioxidant capacity in food
• Markers in Diabetes mellitus and cardiovascular disease
• Biochemical markers in Diabetes mellitus
• Chemotherapy with redesigned Methotrexate
• The Biosynthesis of triglycerides or triacylglycerides
• Consequences of suffering from coronary disease
• What medications should be administered in patients with osteoporosis?
• Appearances of physiological alterations in older adults
• The impact of the administration of clindamycin, amikacin, and ceftazidime in hospitalized patients
• Pharmaceutical advice to reduce stress
• Dyslipidemia in Diabetes mellitus
• Diabetes mellitus and transcription factors (Cell culture)
• Factors that lead to cholesterol excretion
• Nutritional evaluation of pregnant diabetic mothers
• How do blood alcohol levels influence drivers involved in traffic accidents?
• Pleiotropic effects of oral hypoglycemic drugs
• Importance of eating foods rich in carotenoids
• The biochemical and toxicological impact of lead with environmental contact
• The importance of emotions in the intervention of our digestive system
• Lifestyles and Diabetes mellitus
• Adiposity in Diabetes mellitus
• Diabetological education of the patient with Diabetes mellitus
• The impact of drug administration

Read More:  Nursing Research Topics

Nano / Nuclear Chemistry research topics

• Modeling of metallic nanostructures
• Modeling of nanostructures supported on oxides
• Development of advanced nanomaterials with specific
• Nanomaterials in the fight against cancer and spinal cord injuries in laboratory rats for neuronal reconnection
• Study of the effects of radiation on the structure and properties of nanomaterials
• Development of nanostructured substrates for Raman spectroscopy applications
• Implants in neural tissues of the spinal cord to promote lost communication between the brain and the rest of the body
• Design and preparation of theragnostic radiopharmaceuticals
• Research and development of radiopharmaceuticals based on nanosystems for use in molecular nuclear medicine
• Hydrogen storage, the capture of toxic gases, improvement of solar cells
• Geometric optimization of nanostructures using classical methods
• Calculation of energies and molecular properties
• Synthesis of supercapacitors with carbon nanotubes
• Simulation of high-resolution transmission electron microscopy images of nanostructures
• Development of bactericidal dressings based on metallic nanoparticles
• Modernization of the ININ X-Ray Diffraction Laboratory
• Thin coatings of transparent materials with high hardness

Read More:  Psychology Research Paper Topics

Green Chemistry research topics

• Green chemistry and environmental sustainability
• Strategies to make organocatalysis “greener”
• The Chemical Knowledge and Environmental Question
• Approach to school green chemistry, through green protocols
• Sustainable Chemistry: Nature, purposes, and scope
• Postgraduate studies in sustainable chemistry
• Didactic knowledge of the content on green chemistry
• Photochemical synthesis by sunlight
• Green Chemistry: A Present and Future Theme for Chemistry Education
• The environmental dimension of experimentation in the teaching of chemistry
• Role of Chemistry and its teaching in the construction of a sustainable future
• A foundation for the incorporation of green chemistry in organic chemistry curricula
• Contribution of green chemistry to the construction of a socially responsible science
• Aspects of the pedagogical knowledge of the content of green chemistry in university professors of chemistry
• Asymmetric organocatalyzed reactions in the absence of a solvent
• Green Chemistry for Postgraduates

Read More:  Social Work Research Topics

Archaeological Chemistry research topics

• Archaeochemistry of the United States
• Archaeochemistry of Egyptian Pyramids
• Archaeochemistry of Mohanjodaro
• Archaeochemistry of Cambodia
• Archaeological dating, characterization, prospecting, and conservation
• The role of bio-deteriorated ceramics in the formation processes of archaeological sites
• Study of biodeterioration in archaeological ceramics from Mayan Ruins
• Deterioration of ceramic fragments due to the action of lichens
• Applicability of preventive conservation to archaeological ceramics impacted by biodeterioration

Our highly skilled professionals have provided you with superb research topics in chemistry. You can choose anyone matching your speciality and start working on making your paper a piece of art.

Conclusion:

Never believe anyone who says you can’t go for a chemistry degree or PhD. Just listen to your heart and it will all make sense. Chemistry is one of the coolest subjects. If you do it right, with a chemistry research topic that inspires you, then no one can stop you from having your chemical breakthrough. Believe in yourself and the world will see your success like a mushroom cloud. 

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PERSPECTIVE article

This article is part of the research topic.

Organic Chemistry Education Research into Practice

Ungrading in organic chemistry: Students assessing themselves and reflecting on their learning Provisionally Accepted

• 1 Eckerd College, United States

The final, formatted version of the article will be published soon.

The focus on grades has diminished the focus on learning. One strategy that aims to return students' attention to what they are actually learning (and not just earning) is ungrading. Ungrading is thought of as any strategy in which instructors do not assign a number or letter grade to students' assignments and assessments. Instead, faculty may 1) provide thorough feedback and engage in dialogue with students about their work, and perhaps, 2) allow students to assign their own grade. Whichever style of ungrading they choose, the scholars that have been forging the path for ungrading come from a variety of fields and perspectives, including STEM instructors in more recent years. The focus on incorporating ungrading practices into the organic chemistry curriculum provided here is adapted from a variety of practitioners, and especially the foundational work of chemistry professor Clarissa Sorensen-Unruh. In addition to discussing the current ungrading practices in various fields, we will use this perspective article to share our own experience with and lessons learned from beginning to incorporate ungrading in the undergraduate organic chemistry curriculum, both as it relates to the implementation of the practice and our own perceptions of the student experience and learning outcomes. Ultimately, the goal is to allow students to see the significance of the process of learning and to engage in some metacognitive work that they can apply to different assignments, whether in our class or not. If we want students to focus on learning, perhaps they should do the grading themselves.

Keywords: Grading, Ungrading, Organic Chemistry, Chemistry education research, metacognition

Received: 29 Feb 2024; Accepted: 29 Mar 2024.

Copyright: © 2024 Ferguson and Bonner. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Prof. Jalisa Ferguson, Eckerd College, St. Petersburg, United States

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ACS Meetings & Expos

Acs fall 2024.

Hybrid event

Aug 18–22, 2024

Join us in Denver, Colorado from August 18-22 to get the latest research in chemistry, network, and attend career events. The theme of this meeting is "Elevating Chemistry" and will explore a variety of topics such as:

• Elevating chemistry performance
• Elevating chemistry for the public good
• Elevating safety for graduate students
• Elevating chemical education
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Choose from thousands of oral presentations covering every area of chemistry, attend the poster session, and visit the expo hall to meet vendors and learn about new tools and processes.

Don’t miss the Keynote Events, including the Plenary and the Kavli Lecture Series, exploring the theme of the meeting, and featuring emerging leaders and innovations in chemistry.

In addition to the technical papers, ACS Fall 2024 offers several events to advance your career, explore career paths, and hone your leadership skills.

Our undergraduate student program prepares students for their next step, whether it’s exploring various careers or getting ready for graduate school. The educator events offer tips on effective teaching practices.

Explore all that ACS Fall 2024 has to offer!

Related Events:

28th annual green chemistry & engineering conference, acs africa regional conference on green and sustainable chemistry, 2024 southwest regional meeting, acs institute.

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