How to write a case study — examples, templates, and tools

How to write a case study — examples, templates, and tools marquee

It’s a marketer’s job to communicate the effectiveness of a product or service to potential and current customers to convince them to buy and keep business moving. One of the best methods for doing this is to share success stories that are relatable to prospects and customers based on their pain points, experiences, and overall needs.

That’s where case studies come in. Case studies are an essential part of a content marketing plan. These in-depth stories of customer experiences are some of the most effective at demonstrating the value of a product or service. Yet many marketers don’t use them, whether because of their regimented formats or the process of customer involvement and approval.

A case study is a powerful tool for showcasing your hard work and the success your customer achieved. But writing a great case study can be difficult if you’ve never done it before or if it’s been a while. This guide will show you how to write an effective case study and provide real-world examples and templates that will keep readers engaged and support your business.

In this article, you’ll learn:

What is a case study?

How to write a case study, case study templates, case study examples, case study tools.

A case study is the detailed story of a customer’s experience with a product or service that demonstrates their success and often includes measurable outcomes. Case studies are used in a range of fields and for various reasons, from business to academic research. They’re especially impactful in marketing as brands work to convince and convert consumers with relatable, real-world stories of actual customer experiences.

The best case studies tell the story of a customer’s success, including the steps they took, the results they achieved, and the support they received from a brand along the way. To write a great case study, you need to:

  • Celebrate the customer and make them — not a product or service — the star of the story.
  • Craft the story with specific audiences or target segments in mind so that the story of one customer will be viewed as relatable and actionable for another customer.
  • Write copy that is easy to read and engaging so that readers will gain the insights and messages intended.
  • Follow a standardized format that includes all of the essentials a potential customer would find interesting and useful.
  • Support all of the claims for success made in the story with data in the forms of hard numbers and customer statements.

Case studies are a type of review but more in depth, aiming to show — rather than just tell — the positive experiences that customers have with a brand. Notably, 89% of consumers read reviews before deciding to buy, and 79% view case study content as part of their purchasing process. When it comes to B2B sales, 52% of buyers rank case studies as an important part of their evaluation process.

Telling a brand story through the experience of a tried-and-true customer matters. The story is relatable to potential new customers as they imagine themselves in the shoes of the company or individual featured in the case study. Showcasing previous customers can help new ones see themselves engaging with your brand in the ways that are most meaningful to them.

Besides sharing the perspective of another customer, case studies stand out from other content marketing forms because they are based on evidence. Whether pulling from client testimonials or data-driven results, case studies tend to have more impact on new business because the story contains information that is both objective (data) and subjective (customer experience) — and the brand doesn’t sound too self-promotional.

89% of consumers read reviews before buying, 79% view case studies, and 52% of B2B buyers prioritize case studies in the evaluation process.

Case studies are unique in that there’s a fairly standardized format for telling a customer’s story. But that doesn’t mean there isn’t room for creativity. It’s all about making sure that teams are clear on the goals for the case study — along with strategies for supporting content and channels — and understanding how the story fits within the framework of the company’s overall marketing goals.

Here are the basic steps to writing a good case study.

1. Identify your goal

Start by defining exactly who your case study will be designed to help. Case studies are about specific instances where a company works with a customer to achieve a goal. Identify which customers are likely to have these goals, as well as other needs the story should cover to appeal to them.

The answer is often found in one of the buyer personas that have been constructed as part of your larger marketing strategy. This can include anything from new leads generated by the marketing team to long-term customers that are being pressed for cross-sell opportunities. In all of these cases, demonstrating value through a relatable customer success story can be part of the solution to conversion.

2. Choose your client or subject

Who you highlight matters. Case studies tie brands together that might otherwise not cross paths. A writer will want to ensure that the highlighted customer aligns with their own company’s brand identity and offerings. Look for a customer with positive name recognition who has had great success with a product or service and is willing to be an advocate.

The client should also match up with the identified target audience. Whichever company or individual is selected should be a reflection of other potential customers who can see themselves in similar circumstances, having the same problems and possible solutions.

Some of the most compelling case studies feature customers who:

  • Switch from one product or service to another while naming competitors that missed the mark.
  • Experience measurable results that are relatable to others in a specific industry.
  • Represent well-known brands and recognizable names that are likely to compel action.
  • Advocate for a product or service as a champion and are well-versed in its advantages.

Whoever or whatever customer is selected, marketers must ensure they have the permission of the company involved before getting started. Some brands have strict review and approval procedures for any official marketing or promotional materials that include their name. Acquiring those approvals in advance will prevent any miscommunication or wasted effort if there is an issue with their legal or compliance teams.

3. Conduct research and compile data

Substantiating the claims made in a case study — either by the marketing team or customers themselves — adds validity to the story. To do this, include data and feedback from the client that defines what success looks like. This can be anything from demonstrating return on investment (ROI) to a specific metric the customer was striving to improve. Case studies should prove how an outcome was achieved and show tangible results that indicate to the customer that your solution is the right one.

This step could also include customer interviews. Make sure that the people being interviewed are key stakeholders in the purchase decision or deployment and use of the product or service that is being highlighted. Content writers should work off a set list of questions prepared in advance. It can be helpful to share these with the interviewees beforehand so they have time to consider and craft their responses. One of the best interview tactics to keep in mind is to ask questions where yes and no are not natural answers. This way, your subject will provide more open-ended responses that produce more meaningful content.

4. Choose the right format

There are a number of different ways to format a case study. Depending on what you hope to achieve, one style will be better than another. However, there are some common elements to include, such as:

  • An engaging headline
  • A subject and customer introduction
  • The unique challenge or challenges the customer faced
  • The solution the customer used to solve the problem
  • The results achieved
  • Data and statistics to back up claims of success
  • A strong call to action (CTA) to engage with the vendor

It’s also important to note that while case studies are traditionally written as stories, they don’t have to be in a written format. Some companies choose to get more creative with their case studies and produce multimedia content, depending on their audience and objectives. Case study formats can include traditional print stories, interactive web or social content, data-heavy infographics, professionally shot videos, podcasts, and more.

5. Write your case study

We’ll go into more detail later about how exactly to write a case study, including templates and examples. Generally speaking, though, there are a few things to keep in mind when writing your case study.

  • Be clear and concise. Readers want to get to the point of the story quickly and easily, and they’ll be looking to see themselves reflected in the story right from the start.
  • Provide a big picture. Always make sure to explain who the client is, their goals, and how they achieved success in a short introduction to engage the reader.
  • Construct a clear narrative. Stick to the story from the perspective of the customer and what they needed to solve instead of just listing product features or benefits.
  • Leverage graphics. Incorporating infographics, charts, and sidebars can be a more engaging and eye-catching way to share key statistics and data in readable ways.
  • Offer the right amount of detail. Most case studies are one or two pages with clear sections that a reader can skim to find the information most important to them.
  • Include data to support claims. Show real results — both facts and figures and customer quotes — to demonstrate credibility and prove the solution works.

6. Promote your story

Marketers have a number of options for distribution of a freshly minted case study. Many brands choose to publish case studies on their website and post them on social media. This can help support SEO and organic content strategies while also boosting company credibility and trust as visitors see that other businesses have used the product or service.

Marketers are always looking for quality content they can use for lead generation. Consider offering a case study as gated content behind a form on a landing page or as an offer in an email message. One great way to do this is to summarize the content and tease the full story available for download after the user takes an action.

Sales teams can also leverage case studies, so be sure they are aware that the assets exist once they’re published. Especially when it comes to larger B2B sales, companies often ask for examples of similar customer challenges that have been solved.

Now that you’ve learned a bit about case studies and what they should include, you may be wondering how to start creating great customer story content. Here are a couple of templates you can use to structure your case study.

Template 1 — Challenge-solution-result format

  • Start with an engaging title. This should be fewer than 70 characters long for SEO best practices. One of the best ways to approach the title is to include the customer’s name and a hint at the challenge they overcame in the end.
  • Create an introduction. Lead with an explanation as to who the customer is, the need they had, and the opportunity they found with a specific product or solution. Writers can also suggest the success the customer experienced with the solution they chose.
  • Present the challenge. This should be several paragraphs long and explain the problem the customer faced and the issues they were trying to solve. Details should tie into the company’s products and services naturally. This section needs to be the most relatable to the reader so they can picture themselves in a similar situation.
  • Share the solution. Explain which product or service offered was the ideal fit for the customer and why. Feel free to delve into their experience setting up, purchasing, and onboarding the solution.
  • Explain the results. Demonstrate the impact of the solution they chose by backing up their positive experience with data. Fill in with customer quotes and tangible, measurable results that show the effect of their choice.
  • Ask for action. Include a CTA at the end of the case study that invites readers to reach out for more information, try a demo, or learn more — to nurture them further in the marketing pipeline. What you ask of the reader should tie directly into the goals that were established for the case study in the first place.

Template 2 — Data-driven format

  • Start with an engaging title. Be sure to include a statistic or data point in the first 70 characters. Again, it’s best to include the customer’s name as part of the title.
  • Create an overview. Share the customer’s background and a short version of the challenge they faced. Present the reason a particular product or service was chosen, and feel free to include quotes from the customer about their selection process.
  • Present data point 1. Isolate the first metric that the customer used to define success and explain how the product or solution helped to achieve this goal. Provide data points and quotes to substantiate the claim that success was achieved.
  • Present data point 2. Isolate the second metric that the customer used to define success and explain what the product or solution did to achieve this goal. Provide data points and quotes to substantiate the claim that success was achieved.
  • Present data point 3. Isolate the final metric that the customer used to define success and explain what the product or solution did to achieve this goal. Provide data points and quotes to substantiate the claim that success was achieved.
  • Summarize the results. Reiterate the fact that the customer was able to achieve success thanks to a specific product or service. Include quotes and statements that reflect customer satisfaction and suggest they plan to continue using the solution.
  • Ask for action. Include a CTA at the end of the case study that asks readers to reach out for more information, try a demo, or learn more — to further nurture them in the marketing pipeline. Again, remember that this is where marketers can look to convert their content into action with the customer.

While templates are helpful, seeing a case study in action can also be a great way to learn. Here are some examples of how Adobe customers have experienced success.

Juniper Networks

One example is the Adobe and Juniper Networks case study , which puts the reader in the customer’s shoes. The beginning of the story quickly orients the reader so that they know exactly who the article is about and what they were trying to achieve. Solutions are outlined in a way that shows Adobe Experience Manager is the best choice and a natural fit for the customer. Along the way, quotes from the client are incorporated to help add validity to the statements. The results in the case study are conveyed with clear evidence of scale and volume using tangible data.

A Lenovo case study showing statistics, a pull quote and featured headshot, the headline "The customer is king.," and Adobe product links.

The story of Lenovo’s journey with Adobe is one that spans years of planning, implementation, and rollout. The Lenovo case study does a great job of consolidating all of this into a relatable journey that other enterprise organizations can see themselves taking, despite the project size. This case study also features descriptive headers and compelling visual elements that engage the reader and strengthen the content.

Tata Consulting

When it comes to using data to show customer results, this case study does an excellent job of conveying details and numbers in an easy-to-digest manner. Bullet points at the start break up the content while also helping the reader understand exactly what the case study will be about. Tata Consulting used Adobe to deliver elevated, engaging content experiences for a large telecommunications client of its own — an objective that’s relatable for a lot of companies.

Case studies are a vital tool for any marketing team as they enable you to demonstrate the value of your company’s products and services to others. They help marketers do their job and add credibility to a brand trying to promote its solutions by using the experiences and stories of real customers.

When you’re ready to get started with a case study:

  • Think about a few goals you’d like to accomplish with your content.
  • Make a list of successful clients that would be strong candidates for a case study.
  • Reach out to the client to get their approval and conduct an interview.
  • Gather the data to present an engaging and effective customer story.

Adobe can help

There are several Adobe products that can help you craft compelling case studies. Adobe Experience Platform helps you collect data and deliver great customer experiences across every channel. Once you’ve created your case studies, Experience Platform will help you deliver the right information to the right customer at the right time for maximum impact.

To learn more, watch the Adobe Experience Platform story .

Keep in mind that the best case studies are backed by data. That’s where Adobe Real-Time Customer Data Platform and Adobe Analytics come into play. With Real-Time CDP, you can gather the data you need to build a great case study and target specific customers to deliver the content to the right audience at the perfect moment.

Watch the Real-Time CDP overview video to learn more.

Finally, Adobe Analytics turns real-time data into real-time insights. It helps your business collect and synthesize data from multiple platforms to make more informed decisions and create the best case study possible.

Request a demo to learn more about Adobe Analytics.

https://business.adobe.com/blog/perspectives/b2b-ecommerce-10-case-studies-inspire-you

https://business.adobe.com/blog/basics/business-case

https://business.adobe.com/blog/basics/what-is-real-time-analytics

How to write a case study — examples, templates, and tools card image

28 Case Study Examples Every Marketer Should See

Caroline Forsey

Published: March 08, 2023

Putting together a compelling case study is one of the most powerful strategies for showcasing your product and attracting future customers. But it's not easy to create case studies that your audience can’t wait to read.

marketer reviewing case study examples

In this post, we’ll go over the definition of a case study and the best examples to inspire you.

Download Now: 3 Free Case Study Templates

What is a case study?

A case study is a detailed story of something your company did. It includes a beginning — often discussing a conflict, an explanation of what happened next, and a resolution that explains how the company solved or improved on something.

A case study proves how your product has helped other companies by demonstrating real-life results. Not only that, but marketing case studies with solutions typically contain quotes from the customer. This means that they’re not just ads where you praise your own product. Rather, other companies are praising your company — and there’s no stronger marketing material than a verbal recommendation or testimonial. A great case study is also filled with research and stats to back up points made about a project's results.

There are myriad ways to use case studies in your marketing strategy . From featuring them on your website to including them in a sales presentation, a case study is a strong, persuasive tool that shows customers why they should work with you — straight from another customer. Writing one from scratch is hard, though, which is why we’ve created a collection of case study templates for you to get started.

Fill out the form below to access the free case study templates.

case study values example

Free Case Study Templates

Showcase your company's success using these three free case study templates.

  • Data-Driven Case Study Template
  • Product-Specific Case Study Template
  • General Case Study Template

You're all set!

Click this link to access this resource at any time.

There’s no better way to generate more leads than by writing case studies . But without case study examples to draw inspiration from, it can be difficult to write impactful studies that convince visitors to submit a form.

Marketing Case Study Examples

To help you create an attractive and high-converting case study, we've put together a list of some of our favorites. This list includes famous case studies in marketing, technology, and business.

These studies can show you how to frame your company offers in a way that is both meaningful and useful to your audience. So, take a look, and let these examples inspire your next brilliant case study design.

These marketing case studies with solutions show the value proposition of each product. They also show how each company benefited in both the short and long term using quantitative data. In other words, you don’t get just nice statements, like "This company helped us a lot." You see actual change within the firm through numbers and figures.

You can put your learnings into action with HubSpot's Free Case Study Templates . Available as custom designs and text-based documents, you can upload these templates to your CMS or send them to prospects as you see fit.

case study template

1. " How Handled Scaled from Zero to 121 Locations with the Help of HubSpot ," by HubSpot

Case study examples: Handled and HubSpot

What's interesting about this case study is the way it leads with the customer. That reflects a major HubSpot cornerstone, which is to always solve for the customer first. The copy leads with a brief description of why the CEO of Handled founded the company and why he thought Handled could benefit from adopting a CRM. The case study also opens up with one key data point about Handled’s success using HubSpot, namely that it grew to 121 locations.

Notice that this case study uses mixed media. Yes, there is a short video, but it's elaborated upon in the other text on the page. So while your case studies can use one or the other, don't be afraid to combine written copy with visuals to emphasize the project's success.

Key Learnings from the HubSpot Case Study Example

  • Give the case study a personal touch by focusing on the CEO rather than the company itself.
  • Use multimedia to engage website visitors as they read the case study.

2. " The Whole Package ," by IDEO

Case study examples: IDEO and H&M

Here's a design company that knows how to lead with simplicity in its case studies. As soon as the visitor arrives at the page, they’re greeted with a big, bold photo and the title of the case study — which just so happens to summarize how IDEO helped its client. It summarizes the case study in three snippets: The challenge, the impact, and the outcome.

Immediately, IDEO communicates its impact — the company partnered with H&M to remove plastic from its packaging — but it doesn't stop there. As the user scrolls down, the challenge, impact, and progress are elaborated upon with comprehensive (but not overwhelming) copy that outlines what that process looked like, replete with quotes and intriguing visuals.

Key Learnings from the IDEO Case Study Example

  • Split up the takeaways of your case studies into bite-sized sections.
  • Always use visuals and images to enrich the case study experience, especially if it’s a comprehensive case study.

3. " Rozum Robotics intensifies its PR game with Awario ," by Awario

Case study example from Awario

In this case study, Awario greets the user with a summary straight away — so if you’re feeling up to reading the entire case study, you can scan the snapshot and understand how the company serves its customers. The case study then includes jump links to several sections, such as "Company Profile," "Rozum Robotics' Pains," "Challenge," "Solution," and "Results and Improvements."

The sparse copy and prominent headings show that you don’t need a lot of elaborate information to show the value of your products and services. Like the other case study examples on this list, it includes visuals and quotes to demonstrate the effectiveness of the company’s efforts. The case study ends with a bulleted list that shows the results.

Key Learnings from the Awario Robotics Case Study Example

  • Create a table of contents to make your case study easier to navigate.
  • Include a bulleted list of the results you achieved for your client.

4. " Chevrolet DTU ," by Carol H. Williams

Case study examples: Carol H. Williams and Chevrolet DTU

If you’ve worked with a company that’s well-known, use only the name in the title — like Carol H. Williams, one of the nation’s top advertising agencies, does here. The "DTU," stands for "Discover the Unexpected." It generates interest because you want to find out what the initials mean.

They keep your interest in this case study by using a mixture of headings, images, and videos to describe the challenges, objectives, and solutions of the project. The case study closes with a summary of the key achievements that Chevrolet’s DTU Journalism Fellows reached during the project.

Key Learnings from the Carol H. Williams Case Study Example

  • If you’ve worked with a big brand before, consider only using the name in the title — just enough to pique interest.
  • Use a mixture of headings and subheadings to guide users through the case study.

5. " How Fractl Earned Links from 931 Unique Domains for Porch.com in a Single Year ," by Fractl

Case study example from Fractl

Fractl uses both text and graphic design in their Porch.com case study to immerse the viewer in a more interesting user experience. For instance, as you scroll, you'll see the results are illustrated in an infographic-design form as well as the text itself.

Further down the page, they use icons like a heart and a circle to illustrate their pitch angles, and graphs to showcase their results. Rather than writing which publications have mentioned Porch.com during Fractl’s campaign, they incorporated the media outlets’ icons for further visual diversity.

Key Learnings from the Fractl Case Study Example

  • Let pictures speak for you by incorporating graphs, logos, and icons all throughout the case study.
  • Start the case study by right away stating the key results, like Fractl does, instead of putting the results all the way at the bottom.

6. " The Met ," by Fantasy

Case study example from Fantasy

What's the best way to showcase the responsiveness and user interface of a website? Probably by diving right into it with a series of simple showcases— which is exactly what Fantasy does on their case study page for the Metropolitan Museum of Art. They keep the page simple and clean, inviting you to review their redesign of the Met’s website feature-by-feature.

Each section is simple, showing a single piece of the new website's interface so that users aren’t overwhelmed with information and can focus on what matters most.

If you're more interested in text, you can read the objective for each feature. Fantasy understands that, as a potential customer, this is all you need to know. Scrolling further, you're greeted with a simple "Contact Us" CTA.

Key Learnings from the Fantasy Case Study Example

  • You don’t have to write a ton of text to create a great case study. Focus on the solution you delivered itself.
  • Include a CTA at the bottom inviting visitors to contact you.

7. " Rovio: How Rovio Grew Into a Gaming Superpower ," by App Annie

Case study example from App Annie

If your client had a lot of positive things to say about you, take a note from App Annie’s Rovio case study and open up with a quote from your client. The case study also closes with a quote, so that the case study doesn’t seem like a promotion written by your marketing team but a story that’s taken straight from your client’s mouth. It includes a photo of a Rovio employee, too.

Another thing this example does well? It immediately includes a link to the product that Rovio used (namely, App Annie Intelligence) at the top of the case study. The case study closes with a call-to-action button prompting users to book a demo.

Key Learnings from the App Annie Case Study Example

  • Feature quotes from your client at the beginning and end of the case study.
  • Include a mention of the product right at the beginning and prompt users to learn more about the product.

8. " Embracing first-party data: 3 success stories from HubSpot ," by Think with Google

Case study examples: Think with Google and HubSpot

Google takes a different approach to text-focused case studies by choosing three different companies to highlight.

The case study is clean and easily scannable. It has sections for each company, with quotes and headers that clarify the way these three distinct stories connect. The simple format also uses colors and text that align with the Google brand.

Another differentiator is the focus on data. This case study is less than a thousand words, but it's packed with useful data points. Data-driven insights quickly and clearly show how the value of leveraging first-party data while prioritizing consumer privacy.

Case studies example: Data focus, Think with Google

Key Learnings from the Think with Google Case Study Example

  • A case study doesn’t need to be long or complex to be powerful.
  • Clear data points are a quick and effective way to prove value.

9. " In-Depth Performance Marketing Case Study ," by Switch

Case study example from Switch

Switch is an international marketing agency based in Malta that knocks it out of the park with this case study. Its biggest challenge is effectively communicating what it did for its client without ever revealing the client’s name. It also effectively keeps non-marketers in the loop by including a glossary of terms on page 4.

The PDF case study reads like a compelling research article, including titles like "In-Depth Performance Marketing Case Study," "Scenario," and "Approach," so that readers get a high-level overview of what the client needed and why they approached Switch. It also includes a different page for each strategy. For instance, if you’d only be interested in hiring Switch for optimizing your Facebook ads, you can skip to page 10 to see how they did it.

The PDF is fourteen pages long but features big fonts and plenty of white space, so viewers can easily skim it in only a few minutes.

Key Learnings from the Switch Case Study Example

  • If you want to go into specialized information, include a glossary of terms so that non-specialists can easily understand.
  • Close with a CTA page in your case study PDF and include contact information for prospective clients.

10. " Gila River ," by OH Partners

Case study example from OH Partners

Let pictures speak for you, like OH Partners did in this case study. While you’ll quickly come across a heading and some text when you land on this case study page, you’ll get the bulk of the case study through examples of actual work OH Partners did for its client. You will see OH Partners’ work in a billboard, magazine, and video. This communicates to website visitors that if they work with OH Partners, their business will be visible everywhere.

And like the other case studies here, it closes with a summary of what the firm achieved for its client in an eye-catching way.

Key Learnings from the OH Partners Case Study Example

  • Let the visuals speak by including examples of the actual work you did for your client — which is especially useful for branding and marketing agencies.
  • Always close out with your achievements and how they impacted your client.

11. " Facing a Hater ," by Digitas

Case study example from Digitas

Digitas' case study page for Sprite’s #ILOVEYOUHATER campaign keeps it brief while communicating the key facts of Digitas’ work for the popular soda brand. The page opens with an impactful image of a hundred people facing a single man. It turns out, that man is the biggest "bully" in Argentina, and the people facing him are those whom he’s bullied before.

Scrolling down, it's obvious that Digitas kept Sprite at the forefront of their strategy, but more than that, they used real people as their focal point. They leveraged the Twitter API to pull data from Tweets that people had actually tweeted to find the identity of the biggest "hater" in the country. That turned out to be @AguanteElCofler, a Twitter user who has since been suspended.

Key Learnings from the Digitas Case Study Example

  • If a video was part of your work for your client, be sure to include the most impactful screenshot as the heading.
  • Don’t be afraid to provide details on how you helped your client achieve their goals, including the tools you leveraged.

12. " Better Experiences for All ," by HermanMiller

Case study example from HermanMiller

HermanMiller sells sleek, utilitarian furniture with no frills and extreme functionality, and that ethos extends to its case study page for a hospital in Dubai.

What first attracted me to this case study was the beautiful video at the top and the clean user experience. User experience matters a lot in a case study. It determines whether users will keep reading or leave. Another notable aspect of this case study is that the video includes closed-captioning for greater accessibility, and users have the option of expanding the CC and searching through the text.

HermanMiller’s case study also offers an impressive amount of information packed in just a few short paragraphs for those wanting to understand the nuances of their strategy. It closes out with a quote from their client and, most importantly, the list of furniture products that the hospital purchased from the brand.

Key Learnings from the HermanMiller Case Study Example

  • Close out with a list of products that users can buy after reading the case study.
  • Include accessibility features such as closed captioning and night mode to make your case study more user-friendly.

13. " Capital One on AWS ," by Amazon

Case study example from Amazon AWS

Do you work continuously with your clients? Consider structuring your case study page like Amazon did in this stellar case study example. Instead of just featuring one article about Capital One and how it benefited from using AWS, Amazon features a series of articles that you can then access if you’re interested in reading more. It goes all the way back to 2016, all with different stories that feature Capital One’s achievements using AWS.

This may look unattainable for a small firm, but you don’t have to go to extreme measures and do it for every single one of your clients. You could choose the one you most wish to focus on and establish a contact both on your side and your client’s for coming up with the content. Check in every year and write a new piece. These don’t have to be long, either — five hundred to eight hundred words will do.

Key Learnings from the Amazon AWS Case Study Example

  • Write a new article each year featuring one of your clients, then include links to those articles in one big case study page.
  • Consider including external articles as well that emphasize your client’s success in their industry.

14. " HackReactor teaches the world to code #withAsana ," by Asana

Case study examples: Asana and HackReactor

While Asana's case study design looks text-heavy, there's a good reason. It reads like a creative story, told entirely from the customer's perspective.

For instance, Asana knows you won't trust its word alone on why this product is useful. So, they let Tony Phillips, HackReactor CEO, tell you instead: "We take in a lot of information. Our brains are awful at storage but very good at thinking; you really start to want some third party to store your information so you can do something with it."

Asana features frequent quotes from Phillips to break up the wall of text and humanize the case study. It reads like an in-depth interview and captivates the reader through creative storytelling. Even more, Asana includes in-depth detail about how HackReactor uses Asana. This includes how they build templates and workflows:

"There's a huge differentiator between Asana and other tools, and that’s the very easy API access. Even if Asana isn’t the perfect fit for a workflow, someone like me— a relatively mediocre software engineer—can add functionality via the API to build a custom solution that helps a team get more done."

Key Learnings from the Asana Example

  • Include quotes from your client throughout the case study.
  • Provide extensive detail on how your client worked with you or used your product.

15. " Rips Sewed, Brand Love Reaped ," by Amp Agency

Case study example from Amp Agency

Amp Agency's Patagonia marketing strategy aimed to appeal to a new audience through guerrilla marketing efforts and a coast-to-coast road trip. Their case study page effectively conveys a voyager theme, complete with real photos of Patagonia customers from across the U.S., and a map of the expedition. I liked Amp Agency's storytelling approach best. It captures viewers' attention from start to finish simply because it's an intriguing and unique approach to marketing.

Key Learnings from the Amp Agency Example

  • Open up with a summary that communicates who your client is and why they reached out to you.
  • Like in the other case study examples, you’ll want to close out with a quantitative list of your achievements.

16. " NetApp ," by Evisort

Case study examples: Evisort and NetApp

Evisort opens up its NetApp case study with an at-a-glance overview of the client. It’s imperative to always focus on the client in your case study — not on your amazing product and equally amazing team. By opening up with a snapshot of the client’s company, Evisort places the focus on the client.

This case study example checks all the boxes for a great case study that’s informative, thorough, and compelling. It includes quotes from the client and details about the challenges NetApp faced during the COVID pandemic. It closes out with a quote from the client and with a link to download the case study in PDF format, which is incredibly important if you want your case study to be accessible in a wider variety of formats.

Key Learnings from the Evisort Example

  • Place the focus immediately on your client by including a snapshot of their company.
  • Mention challenging eras, such as a pandemic or recession, to show how your company can help your client succeed even during difficult times.

17. " Copernicus Land Monitoring – CLC+ Core ," by Cloudflight

Case study example from Cloudflight

Including highly specialized information in your case study is an effective way to show prospects that you’re not just trying to get their business. You’re deep within their industry, too, and willing to learn everything you need to learn to create a solution that works specifically for them.

Cloudflight does a splendid job at that in its Copernicus Land Monitoring case study. While the information may be difficult to read at first glance, it will capture the interest of prospects who are in the environmental industry. It thus shows Cloudflight’s value as a partner much more effectively than a general case study would.

The page is comprehensive and ends with a compelling call-to-action — "Looking for a solution that automates, and enhances your Big Data system? Are you struggling with large datasets and accessibility? We would be happy to advise and support you!" The clean, whitespace-heavy page is an effective example of using a case study to capture future leads.

Key Learnings from the Cloudflight Case Study Example

  • Don’t be afraid to get technical in your explanation of what you did for your client.
  • Include a snapshot of the sales representative prospects should contact, especially if you have different sales reps for different industries, like Cloudflight does.

18. " Valvoline Increases Coupon Send Rate by 76% with Textel’s MMS Picture Texting ," by Textel

Case study example from Textel

If you’re targeting large enterprises with a long purchasing cycle, you’ll want to include a wealth of information in an easily transferable format. That’s what Textel does here in its PDF case study for Valvoline. It greets the user with an eye-catching headline that shows the value of using Textel. Valvoline saw a significant return on investment from using the platform.

Another smart decision in this case study is highlighting the client’s quote by putting it in green font and doing the same thing for the client’s results because it helps the reader quickly connect the two pieces of information. If you’re in a hurry, you can also take a look at the "At a Glance" column to get the key facts of the case study, starting with information about Valvoline.

Key Learnings from the Textel Case Study Example

  • Include your client’s ROI right in the title of the case study.
  • Add an "At a Glance" column to your case study PDF to make it easy to get insights without needing to read all the text.

19. " Hunt Club and Happeo — a tech-enabled love story ," by Happeo

Case study example from Happeo

In this blog-post-like case study, Happeo opens with a quote from the client, then dives into a compelling heading: "Technology at the forefront of Hunt Club's strategy." Say you’re investigating Happeo as a solution and consider your firm to be technology-driven. This approach would spark your curiosity about why the client chose to work with Happeo. It also effectively communicates the software’s value proposition without sounding like it’s coming from an in-house marketing team.

Every paragraph is a quote written from the customer’s perspective. Later down the page, the case study also dives into "the features that changed the game for Hunt Club," giving Happeo a chance to highlight some of the platform’s most salient features.

Key Learnings from the Happeo Case Study Example

  • Consider writing the entirety of the case study from the perspective of the customer.
  • Include a list of the features that convinced your client to go with you.

20. " Red Sox Season Campaign ," by CTP Boston

Case study example from CTP Boston

What's great about CTP's case study page for their Red Sox Season Campaign is their combination of video, images, and text. A video automatically begins playing when you visit the page, and as you scroll, you'll see more embedded videos of Red Sox players, a compilation of print ads, and social media images you can click to enlarge.

At the bottom, it says "Find out how we can do something similar for your brand." The page is clean, cohesive, and aesthetically pleasing. It invites viewers to appreciate the well-roundedness of CTP's campaign for Boston's beloved baseball team.

Key Learnings from the CTP Case Study Example

  • Include a video in the heading of the case study.
  • Close with a call-to-action that makes leads want to turn into prospects.

21. " Acoustic ," by Genuine

Case study example from Genuine

Sometimes, simple is key. Genuine's case study for Acoustic is straightforward and minimal, with just a few short paragraphs, including "Reimagining the B2B website experience," "Speaking to marketers 1:1," and "Inventing Together." After the core of the case study, we then see a quote from Acoustic’s CMO and the results Genuine achieved for the company.

The simplicity of the page allows the reader to focus on both the visual aspects and the copy. The page displays Genuine's brand personality while offering the viewer all the necessary information they need.

  • You don’t need to write a lot to create a great case study. Keep it simple.
  • Always include quantifiable data to illustrate the results you achieved for your client.

22. " Using Apptio Targetprocess Automated Rules in Wargaming ," by Apptio

Case study example from Apptio

Apptio’s case study for Wargaming summarizes three key pieces of information right at the beginning: The goals, the obstacles, and the results.

Readers then have the opportunity to continue reading — or they can walk away right then with the information they need. This case study also excels in keeping the human interest factor by formatting the information like an interview.

The piece is well-organized and uses compelling headers to keep the reader engaged. Despite its length, Apptio's case study is appealing enough to keep the viewer's attention. Every Apptio case study ends with a "recommendation for other companies" section, where the client can give advice for other companies that are looking for a similar solution but aren’t sure how to get started.

Key Learnings from the Apptio Case Study Example

  • Put your client in an advisory role by giving them the opportunity to give recommendations to other companies that are reading the case study.
  • Include the takeaways from the case study right at the beginning so prospects quickly get what they need.

23. " Airbnb + Zendesk: building a powerful solution together ," by Zendesk

Case study example from Zendesk

Zendesk's Airbnb case study reads like a blog post, and focuses equally on Zendesk and Airbnb, highlighting a true partnership between the companies. To captivate readers, it begins like this: "Halfway around the globe is a place to stay with your name on it. At least for a weekend."

The piece focuses on telling a good story and provides photographs of beautiful Airbnb locations. In a case study meant to highlight Zendesk's helpfulness, nothing could be more authentic than their decision to focus on Airbnb's service in such great detail.

Key Learnings from the Zendesk Case Study Example

  • Include images of your client’s offerings — not necessarily of the service or product you provided. Notice how Zendesk doesn’t include screenshots of its product.
  • Include a call-to-action right at the beginning of the case study. Zendesk gives you two options: to find a solution or start a trial.

24. " Biobot Customer Success Story: Rollins College, Winter Park, Florida ," by Biobot

Case study example from Biobot

Like some of the other top examples in this list, Biobot opens its case study with a quote from its client, which captures the value proposition of working with Biobot. It mentions the COVID pandemic and goes into detail about the challenges the client faced during this time.

This case study is structured more like a news article than a traditional case study. This format can work in more formal industries where decision-makers need to see in-depth information about the case. Be sure to test different methods and measure engagement .

Key Learnings from the Biobot Case Study Example

  • Mention environmental, public health, or economic emergencies and how you helped your client get past such difficult times.
  • Feel free to write the case study like a normal blog post, but be sure to test different methods to find the one that best works for you.

25. " Discovering Cost Savings With Efficient Decision Making ," by Gartner

Case study example from Gartner

You don't always need a ton of text or a video to convey your message — sometimes, you just need a few paragraphs and bullet points. Gartner does a fantastic job of quickly providing the fundamental statistics a potential customer would need to know, without boggling down their readers with dense paragraphs. The case study closes with a shaded box that summarizes the impact that Gartner had on its client. It includes a quote and a call-to-action to "Learn More."

Key Learnings from the Gartner Case Study Example

  • Feel free to keep the case study short.
  • Include a call-to-action at the bottom that takes the reader to a page that most relates to them.

26. " Bringing an Operator to the Game ," by Redapt

Case study example from Redapt

This case study example by Redapt is another great demonstration of the power of summarizing your case study’s takeaways right at the start of the study. Redapt includes three easy-to-scan columns: "The problem," "the solution," and "the outcome." But its most notable feature is a section titled "Moment of clarity," which shows why this particular project was difficult or challenging.

The section is shaded in green, making it impossible to miss. Redapt does the same thing for each case study. In the same way, you should highlight the "turning point" for both you and your client when you were working toward a solution.

Key Learnings from the Redapt Case Study Example

  • Highlight the turning point for both you and your client during the solution-seeking process.
  • Use the same structure (including the same headings) for your case studies to make them easy to scan and read.

27. " Virtual Call Center Sees 300% Boost In Contact Rate ," by Convoso

Case study example from Convoso

Convoso’s PDF case study for Digital Market Media immediately mentions the results that the client achieved and takes advantage of white space. On the second page, the case study presents more influential results. It’s colorful and engaging and closes with a spread that prompts readers to request a demo.

Key Learnings from the Convoso Case Study Example

  • List the results of your work right at the beginning of the case study.
  • Use color to differentiate your case study from others. Convoso’s example is one of the most colorful ones on this list.

28. " Ensuring quality of service during a pandemic ," by Ericsson

Case study example from Ericsson

Ericsson’s case study page for Orange Spain is an excellent example of using diverse written and visual media — such as videos, graphs, and quotes — to showcase the success a client experienced. Throughout the case study, Ericsson provides links to product and service pages users might find relevant as they’re reading the study.

For instance, under the heading "Preloaded with the power of automation," Ericsson mentions its Ericsson Operations Engine product, then links to that product page. It closes the case study with a link to another product page.

Key Learnings from the Ericsson Case Study Example

  • Link to product pages throughout the case study so that readers can learn more about the solution you offer.
  • Use multimedia to engage users as they read the case study.

Start creating your case study.

Now that you've got a great list of examples of case studies, think about a topic you'd like to write about that highlights your company or work you did with a customer.

A customer’s success story is the most persuasive marketing material you could ever create. With a strong portfolio of case studies, you can ensure prospects know why they should give you their business.

Editor's note: This post was originally published in August 2018 and has been updated for comprehensiveness.

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Showcase your company's success using these free case study templates.

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Blog Graphic Design 15+ Professional Case Study Examples [Design Tips + Templates]

15+ Professional Case Study Examples [Design Tips + Templates]

Written by: Alice Corner Jan 12, 2023

Venngage case study examples

Have you ever bought something — within the last 10 years or so — without reading its reviews or without a recommendation or prior experience of using it?

If the answer is no — or at least, rarely — you get my point.

Positive reviews matter for selling to regular customers, and for B2B or SaaS businesses, detailed case studies are important too.

Wondering how to craft a compelling case study ? No worries—I’ve got you covered with 15 marketing case study templates , helpful tips, and examples to ensure your case study converts effectively.

Click to jump ahead:

  • What is a Case Study?

Business Case Study Examples

Simple case study examples.

  • Marketing Case Study Examples

Sales Case Study Examples

  • Case Study FAQs

What is a case study?

A case study is an in-depth, detailed analysis of a specific real-world situation. For example, a case study can be about an individual, group, event, organization, or phenomenon. The purpose of a case study is to understand its complexities and gain insights into a particular instance or situation.

In the context of a business, however, case studies take customer success stories and explore how they use your product to help them achieve their business goals.

Case Study Definition LinkedIn Post

As well as being valuable marketing tools , case studies are a good way to evaluate your product as it allows you to objectively examine how others are using it.

It’s also a good way to interview your customers about why they work with you.

Related: What is a Case Study? [+6 Types of Case Studies]

Marketing Case Study Template

A marketing case study showcases how your product or services helped potential clients achieve their business goals. You can also create case studies of internal, successful marketing projects. A marketing case study typically includes:

  • Company background and history
  • The challenge
  • How you helped
  • Specific actions taken
  • Visuals or Data
  • Client testimonials

Here’s an example of a marketing case study template:

marketing case study example

Whether you’re a B2B or B2C company, business case studies can be a powerful resource to help with your sales, marketing, and even internal departmental awareness.

Business and business management case studies should encompass strategic insights alongside anecdotal and qualitative findings, like in the business case study examples below.

Conduct a B2B case study by researching the company holistically

When it comes to writing a case study, make sure you approach the company holistically and analyze everything from their social media to their sales.

Think about every avenue your product or service has been of use to your case study company, and ask them about the impact this has had on their wider company goals.

Venngage orange marketing case study example

In business case study examples like the one above, we can see that the company has been thought about holistically simply by the use of icons.

By combining social media icons with icons that show in-person communication we know that this is a well-researched and thorough case study.

This case study report example could also be used within an annual or end-of-year report.

Highlight the key takeaway from your marketing case study

To create a compelling case study, identify the key takeaways from your research. Use catchy language to sum up this information in a sentence, and present this sentence at the top of your page.

This is “at a glance” information and it allows people to gain a top-level understanding of the content immediately. 

Purple SAAS Business Case Study Template

You can use a large, bold, contrasting font to help this information stand out from the page and provide interest.

Learn  how to choose fonts  effectively with our Venngage guide and once you’ve done that.

Upload your fonts and  brand colors  to Venngage using the  My Brand Kit  tool and see them automatically applied to your designs.

The heading is the ideal place to put the most impactful information, as this is the first thing that people will read.

In this example, the stat of “Increase[d] lead quality by 90%” is used as the header. It makes customers want to read more to find out how exactly lead quality was increased by such a massive amount.

Purple SAAS Business Case Study Template Header

If you’re conducting an in-person interview, you could highlight a direct quote or insight provided by your interview subject.

Pick out a catchy sentence or phrase, or the key piece of information your interview subject provided and use that as a way to draw a potential customer in.

Use charts to visualize data in your business case studies

Charts are an excellent way to visualize data and to bring statistics and information to life. Charts make information easier to understand and to illustrate trends or patterns.

Making charts is even easier with Venngage.

In this consulting case study example, we can see that a chart has been used to demonstrate the difference in lead value within the Lead Elves case study.

Adding a chart here helps break up the information and add visual value to the case study. 

Red SAAS Business Case Study Template

Using charts in your case study can also be useful if you’re creating a project management case study.

You could use a Gantt chart or a project timeline to show how you have managed the project successfully.

event marketing project management gantt chart example

Use direct quotes to build trust in your marketing case study

To add an extra layer of authenticity you can include a direct quote from your customer within your case study.

According to research from Nielsen , 92% of people will trust a recommendation from a peer and 70% trust recommendations even if they’re from somebody they don’t know.

Case study peer recommendation quote

So if you have a customer or client who can’t stop singing your praises, make sure you get a direct quote from them and include it in your case study.

You can either lift part of the conversation or interview, or you can specifically request a quote. Make sure to ask for permission before using the quote.

Contrast Lead Generation Business Case Study Template

This design uses a bright contrasting speech bubble to show that it includes a direct quote, and helps the quote stand out from the rest of the text.

This will help draw the customer’s attention directly to the quote, in turn influencing them to use your product or service.

Less is often more, and this is especially true when it comes to creating designs. Whilst you want to create a professional-looking, well-written and design case study – there’s no need to overcomplicate things.

These simple case study examples show that smart clean designs and informative content can be an effective way to showcase your successes.

Use colors and fonts to create a professional-looking case study

Business case studies shouldn’t be boring. In fact, they should be beautifully and professionally designed.

This means the normal rules of design apply. Use fonts, colors, and icons to create an interesting and visually appealing case study.

In this case study example, we can see how multiple fonts have been used to help differentiate between the headers and content, as well as complementary colors and eye-catching icons.

Blue Simple Business Case Study Template

Marketing case study examples

Marketing case studies are incredibly useful for showing your marketing successes. Every successful marketing campaign relies on influencing a consumer’s behavior, and a great case study can be a great way to spotlight your biggest wins.

In the marketing case study examples below, a variety of designs and techniques to create impactful and effective case studies.

Show off impressive results with a bold marketing case study

Case studies are meant to show off your successes, so make sure you feature your positive results prominently. Using bold and bright colors as well as contrasting shapes, large bold fonts, and simple icons is a great way to highlight your wins.

In well-written case study examples like the one below, the big wins are highlighted on the second page with a bright orange color and are highlighted in circles.

Making the important data stand out is especially important when attracting a prospective customer with marketing case studies.

Light simplebusiness case study template

Use a simple but clear layout in your case study

Using a simple layout in your case study can be incredibly effective, like in the example of a case study below.

Keeping a clean white background, and using slim lines to help separate the sections is an easy way to format your case study.

Making the information clear helps draw attention to the important results, and it helps improve the  accessibility of the design .

Business case study examples like this would sit nicely within a larger report, with a consistent layout throughout.

Modern lead Generaton Business Case Study Template

Use visuals and icons to create an engaging and branded business case study

Nobody wants to read pages and pages of text — and that’s why Venngage wants to help you communicate your ideas visually.

Using icons, graphics, photos, or patterns helps create a much more engaging design. 

With this Blue Cap case study icons, colors, and impactful pattern designs have been used to create an engaging design that catches your eye.

Social Media Business Case Study template

Use a monochromatic color palette to create a professional and clean case study

Let your research shine by using a monochromatic and minimalistic color palette.

By sticking to one color, and leaving lots of blank space you can ensure your design doesn’t distract a potential customer from your case study content.

Color combination examples

In this case study on Polygon Media, the design is simple and professional, and the layout allows the prospective customer to follow the flow of information.

The gradient effect on the left-hand column helps break up the white background and adds an interesting visual effect.

Gray Lead Generation Business Case Study Template

Did you know you can generate an accessible color palette with Venngage? Try our free accessible color palette generator today and create a case study that delivers and looks pleasant to the eye:

Venngage's accessible color palette generator

Add long term goals in your case study

When creating a case study it’s a great idea to look at both the short term and the long term goals of the company to gain the best understanding possible of the insights they provide.

Short-term goals will be what the company or person hopes to achieve in the next few months, and long-term goals are what the company hopes to achieve in the next few years.

Check out this modern pattern design example of a case study below:

Lead generation business case study template

In this case study example, the short and long-term goals are clearly distinguished by light blue boxes and placed side by side so that they are easy to compare.

Lead generation case study example short term goals

Use a strong introductory paragraph to outline the overall strategy and goals before outlining the specific short-term and long-term goals to help with clarity.

This strategy can also be handy when creating a consulting case study.

Use data to make concrete points about your sales and successes

When conducting any sort of research stats, facts, and figures are like gold dust (aka, really valuable).

Being able to quantify your findings is important to help understand the information fully. Saying sales increased 10% is much more effective than saying sales increased.

While sales dashboards generally tend it make it all about the numbers and charts, in sales case study examples, like this one, the key data and findings can be presented with icons. This contributes to the potential customer’s better understanding of the report.

They can clearly comprehend the information and it shows that the case study has been well researched.

Vibrant Content Marketing Case Study Template

Use emotive, persuasive, or action based language in your marketing case study

Create a compelling case study by using emotive, persuasive and action-based language when customizing your case study template.

Case study example pursuasive language

In this well-written case study example, we can see that phrases such as “Results that Speak Volumes” and “Drive Sales” have been used.

Using persuasive language like you would in a blog post. It helps inspire potential customers to take action now.

Bold Content Marketing Case Study Template

Keep your potential customers in mind when creating a customer case study for marketing

82% of marketers use case studies in their marketing  because it’s such an effective tool to help quickly gain customers’ trust and to showcase the potential of your product.

Why are case studies such an important tool in content marketing?

By writing a case study you’re telling potential customers that they can trust you because you’re showing them that other people do.

Not only that, but if you have a SaaS product, business case studies are a great way to show how other people are effectively using your product in their company.

In this case study, Network is demonstrating how their product has been used by Vortex Co. with great success; instantly showing other potential customers that their tool works and is worth using.

Teal Social Media Business Case Study Template

Related: 10+ Case Study Infographic Templates That Convert

Case studies are particularly effective as a sales technique.

A sales case study is like an extended customer testimonial, not only sharing opinions of your product – but showcasing the results you helped your customer achieve.

Make impactful statistics pop in your sales case study

Writing a case study doesn’t mean using text as the only medium for sharing results.

You should use icons to highlight areas of your research that are particularly interesting or relevant, like in this example of a case study:

Coral content marketing case study template.jpg

Icons are a great way to help summarize information quickly and can act as visual cues to help draw the customer’s attention to certain areas of the page.

In some of the business case study examples above, icons are used to represent the impressive areas of growth and are presented in a way that grabs your attention.

Use high contrast shapes and colors to draw attention to key information in your sales case study

Help the key information stand out within your case study by using high contrast shapes and colors.

Use a complementary or contrasting color, or use a shape such as a rectangle or a circle for maximum impact.

Blue case study example case growth

This design has used dark blue rectangles to help separate the information and make it easier to read.

Coupled with icons and strong statistics, this information stands out on the page and is easily digestible and retainable for a potential customer.

Blue Content Marketing Case Study Tempalte

Case Study Examples Summary

Once you have created your case study, it’s best practice to update your examples on a regular basis to include up-to-date statistics, data, and information.

You should update your business case study examples often if you are sharing them on your website .

It’s also important that your case study sits within your brand guidelines – find out how Venngage’s My Brand Kit tool can help you create consistently branded case study templates.

Case studies are important marketing tools – but they shouldn’t be the only tool in your toolbox. Content marketing is also a valuable way to earn consumer trust.

Case Study FAQ

Why should you write a case study.

Case studies are an effective marketing technique to engage potential customers and help build trust.

By producing case studies featuring your current clients or customers, you are showcasing how your tool or product can be used. You’re also showing that other people endorse your product.

In addition to being a good way to gather positive testimonials from existing customers , business case studies are good educational resources and can be shared amongst your company or team, and used as a reference for future projects.

How should you write a case study?

To create a great case study, you should think strategically. The first step, before starting your case study research, is to think about what you aim to learn or what you aim to prove.

You might be aiming to learn how a company makes sales or develops a new product. If this is the case, base your questions around this.

You can learn more about writing a case study  from our extensive guide.

Related: How to Present a Case Study like a Pro (With Examples)

Some good questions you could ask would be:

  • Why do you use our tool or service?
  • How often do you use our tool or service?
  • What does the process of using our product look like to you?
  • If our product didn’t exist, what would you be doing instead?
  • What is the number one benefit you’ve found from using our tool?

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What is case study research?

Last updated

8 February 2023

Reviewed by

Cathy Heath

Suppose a company receives a spike in the number of customer complaints, or medical experts discover an outbreak of illness affecting children but are not quite sure of the reason. In both cases, carrying out a case study could be the best way to get answers.

Organization

Case studies can be carried out across different disciplines, including education, medicine, sociology, and business.

Most case studies employ qualitative methods, but quantitative methods can also be used. Researchers can then describe, compare, evaluate, and identify patterns or cause-and-effect relationships between the various variables under study. They can then use this knowledge to decide what action to take. 

Another thing to note is that case studies are generally singular in their focus. This means they narrow focus to a particular area, making them highly subjective. You cannot always generalize the results of a case study and apply them to a larger population. However, they are valuable tools to illustrate a principle or develop a thesis.

Analyze case study research

Dovetail streamlines case study research to help you uncover and share actionable insights

  • What are the different types of case study designs?

Researchers can choose from a variety of case study designs. The design they choose is dependent on what questions they need to answer, the context of the research environment, how much data they already have, and what resources are available.

Here are the common types of case study design:

Explanatory

An explanatory case study is an initial explanation of the how or why that is behind something. This design is commonly used when studying a real-life phenomenon or event. Once the organization understands the reasons behind a phenomenon, it can then make changes to enhance or eliminate the variables causing it. 

Here is an example: How is co-teaching implemented in elementary schools? The title for a case study of this subject could be “Case Study of the Implementation of Co-Teaching in Elementary Schools.”

Descriptive

An illustrative or descriptive case study helps researchers shed light on an unfamiliar object or subject after a period of time. The case study provides an in-depth review of the issue at hand and adds real-world examples in the area the researcher wants the audience to understand. 

The researcher makes no inferences or causal statements about the object or subject under review. This type of design is often used to understand cultural shifts.

Here is an example: How did people cope with the 2004 Indian Ocean Tsunami? This case study could be titled "A Case Study of the 2004 Indian Ocean Tsunami and its Effect on the Indonesian Population."

Exploratory

Exploratory research is also called a pilot case study. It is usually the first step within a larger research project, often relying on questionnaires and surveys . Researchers use exploratory research to help narrow down their focus, define parameters, draft a specific research question , and/or identify variables in a larger study. This research design usually covers a wider area than others, and focuses on the ‘what’ and ‘who’ of a topic.

Here is an example: How do nutrition and socialization in early childhood affect learning in children? The title of the exploratory study may be “Case Study of the Effects of Nutrition and Socialization on Learning in Early Childhood.”

An intrinsic case study is specifically designed to look at a unique and special phenomenon. At the start of the study, the researcher defines the phenomenon and the uniqueness that differentiates it from others. 

In this case, researchers do not attempt to generalize, compare, or challenge the existing assumptions. Instead, they explore the unique variables to enhance understanding. Here is an example: “Case Study of Volcanic Lightning.”

This design can also be identified as a cumulative case study. It uses information from past studies or observations of groups of people in certain settings as the foundation of the new study. Given that it takes multiple areas into account, it allows for greater generalization than a single case study. 

The researchers also get an in-depth look at a particular subject from different viewpoints.  Here is an example: “Case Study of how PTSD affected Vietnam and Gulf War Veterans Differently Due to Advances in Military Technology.”

Critical instance

A critical case study incorporates both explanatory and intrinsic study designs. It does not have predetermined purposes beyond an investigation of the said subject. It can be used for a deeper explanation of the cause-and-effect relationship. It can also be used to question a common assumption or myth. 

The findings can then be used further to generalize whether they would also apply in a different environment.  Here is an example: “What Effect Does Prolonged Use of Social Media Have on the Mind of American Youth?”

Instrumental

Instrumental research attempts to achieve goals beyond understanding the object at hand. Researchers explore a larger subject through different, separate studies and use the findings to understand its relationship to another subject. This type of design also provides insight into an issue or helps refine a theory. 

For example, you may want to determine if violent behavior in children predisposes them to crime later in life. The focus is on the relationship between children and violent behavior, and why certain children do become violent. Here is an example: “Violence Breeds Violence: Childhood Exposure and Participation in Adult Crime.”

Evaluation case study design is employed to research the effects of a program, policy, or intervention, and assess its effectiveness and impact on future decision-making. 

For example, you might want to see whether children learn times tables quicker through an educational game on their iPad versus a more teacher-led intervention. Here is an example: “An Investigation of the Impact of an iPad Multiplication Game for Primary School Children.” 

  • When do you use case studies?

Case studies are ideal when you want to gain a contextual, concrete, or in-depth understanding of a particular subject. It helps you understand the characteristics, implications, and meanings of the subject.

They are also an excellent choice for those writing a thesis or dissertation, as they help keep the project focused on a particular area when resources or time may be too limited to cover a wider one. You may have to conduct several case studies to explore different aspects of the subject in question and understand the problem.

  • What are the steps to follow when conducting a case study?

1. Select a case

Once you identify the problem at hand and come up with questions, identify the case you will focus on. The study can provide insights into the subject at hand, challenge existing assumptions, propose a course of action, and/or open up new areas for further research.

2. Create a theoretical framework

While you will be focusing on a specific detail, the case study design you choose should be linked to existing knowledge on the topic. This prevents it from becoming an isolated description and allows for enhancing the existing information. 

It may expand the current theory by bringing up new ideas or concepts, challenge established assumptions, or exemplify a theory by exploring how it answers the problem at hand. A theoretical framework starts with a literature review of the sources relevant to the topic in focus. This helps in identifying key concepts to guide analysis and interpretation.

3. Collect the data

Case studies are frequently supplemented with qualitative data such as observations, interviews, and a review of both primary and secondary sources such as official records, news articles, and photographs. There may also be quantitative data —this data assists in understanding the case thoroughly.

4. Analyze your case

The results of the research depend on the research design. Most case studies are structured with chapters or topic headings for easy explanation and presentation. Others may be written as narratives to allow researchers to explore various angles of the topic and analyze its meanings and implications.

In all areas, always give a detailed contextual understanding of the case and connect it to the existing theory and literature before discussing how it fits into your problem area.

  • What are some case study examples?

What are the best approaches for introducing our product into the Kenyan market?

How does the change in marketing strategy aid in increasing the sales volumes of product Y?

How can teachers enhance student participation in classrooms?

How does poverty affect literacy levels in children?

Case study topics

Case study of product marketing strategies in the Kenyan market

Case study of the effects of a marketing strategy change on product Y sales volumes

Case study of X school teachers that encourage active student participation in the classroom

Case study of the effects of poverty on literacy levels in children

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Case Study Mastery: Examples & Step-by-Step Templates

Master case study: Uncover key strategies to conduct & present findings that influence decisions charachters.

What's Inside?

Understanding and sharing success stories in the business management world is crucial for grasping the growth journey of a business.

In this article, we will delve into the concept of a business management case study, exploring its definition, benefits, limitations, step-by-step process, types, and essential elements.

What is a Case Study?

A case study research is a detailed analysis of a particular subject, often a real-world situation or scenario, to draw insights and conclusions. It serves as a valuable tool for learning from successful strategies, identifying challenges, and making informed decisions.

case study

Key Characteristics of a Case Study:

Specific Focus: Case studies concentrate on a particular subject, narrowing down the scope to delve deeply into specific aspects.

Real-world Context: Unlike theoretical studies, case studies are grounded in the real world. They often involve the examination of actual events, circumstances, or challenges.

Comprehensive Exploration: Case studies involve a thorough investigation of multiple facets of the chosen subject. This may include collecting and analyzing data, conducting interviews, and reviewing relevant documents.

case studies

Contextualization: Each case study is set within a context, providing background information to help readers or viewers understand the circumstances surrounding the case.

Problem-Solving Orientation: While exploring the intricacies of a case, case studies often aim to identify problems, challenges, or opportunities. They can be used as tools for problem-solving and decision-making.

In-depth Analysis: The analysis in a case study goes beyond surface-level observations. It involves a detailed examination of factors contributing to the situation, allowing for a nuanced understanding.

Presentation of Findings: A case study concludes with the presentation of findings, insights, and conclusions. Leveraging a visually compelling presentation plays a vital role for a case study to speak out.

presentation

Why You Should Write a Case Study?

Writing a case study offers several compelling reasons for individuals and businesses alike:

Demonstrate Success: A case study allows you to showcase your achievements and successes. It provides tangible evidence of your capabilities, helping build trust and credibility with potential clients, customers, or collaborators.

Demonstrate Success

Educate and Inform: Use case studies to share valuable insights, lessons learned, and best practices. By documenting your experiences, you contribute to the collective knowledge within your industry, positioning yourself as an authority and resource.

Problem-Solving Showcase: If your case study revolves around overcoming challenges, it highlights your problem-solving abilities. This can be particularly impactful in industries where complex issues require innovative solutions.

Engage Your Audience: Well-crafted case studies are engaging and resonate with your audience. They tell a story, making information more relatable and memorable. This storytelling aspect can captivate readers and enhance their understanding of your work.

Engage Your Audience

Build Brand Awareness: Case studies provide an opportunity to promote your brand in a context that goes beyond traditional marketing. Through real-world examples, you can reinforce your brand message and values.

Attract New Opportunities: A compelling case study can attract new opportunities, whether it be clients, partnerships , or collaborations. It serves as a powerful marketing tool, showcasing your expertise and capabilities to a wider audience.

Validate Your Methods: For businesses, case studies serve as a validation of their methods and strategies. Employing a robust case study methodology is a way to demonstrate the effectiveness of your products, services, or approaches to potential clients or customers through a thorough research process.

Internal Learning: Writing a case study requires reflection on your processes and approach case outcomes. This internal learning process can contribute to continuous improvement within your organization , fostering a culture of innovation and adaptability.

Internal Learning

SEO Benefits: Case studies can be optimized for search engines, contributing to your online visibility. Including relevant keywords and internal links in your case studies can improve your website's SEO , attracting more organic traffic.

Differentiation: In competitive industries, a well crafted case study sets you apart from the competition. It allows you to highlight what makes your approach unique and why clients or customers should choose your products or services.

Benefits and Limitations of Case Studies

 Limitations of Case Studies

Benefits of Case Studies:

  • Evident Success Stories: Case studies serve as tangible evidence of a business's success, allowing them to showcase real-world achievements and build credibility with potential clients or customers.
  • Effective Marketing Tool: They function as powerful marketing tools by providing in depth insights into a business's capabilities , differentiating it from competitors, and influencing the decision making process of potential clients.
  • Client Relationship Building: Through detailed case studies, businesses can strengthen relationships with existing clients by demonstrating their commitment, problem solving abilities, and delivering measurable results.
  • Versatile Content: Case studies offer versatile content that can be repurposed across various marketing channels, including websites, social media, presentations, and promotional materials.
  • Educational Value: Businesses can use case studies to educate their target audience about their industry, innovative solutions, and best practices, positioning themselves as thought leaders.

Limitations of Case Studies:

  • Resource Intensive: Creating comprehensive case studies demands significant resources, including time, effort, and potential costs, making them resource-intensive for businesses.
  • Limited Generalization: Findings from a specific case study may not be universally applicable, limiting their generalizability to other scenarios or industries.
  • Potential Bias: There is a risk of bias in the selection and presentation of information, as businesses may be inclined to emphasize positive outcomes and downplay challenges.
  • Confidentiality Concerns: Businesses may face challenges in sharing detailed information, especially if it involves sensitive data or strategies, raising concerns about confidentiality.
  • Difficulty in Replication: The unique circumstances of a case study may make it challenging to replicate the same success in different contexts, limiting the broader applicability of the insights gained.

How to Conduct a Case Analysis: Step-by-step

1. define the objective:.

  • Clearly outline the purpose of the case study. What do you aim to achieve or understand through this analysis?

purpose of the case study

2. Select the Case:

  • Identify a relevant and specific case that aligns with your objective. For an important case study this could be a real-world situation, event, or phenomenon.

3. Background Research:

  • Gather background information about the case. This may include historical context, key players involved, and any existing literature on the subject.

Background Research

4. Identify Key Issues or Questions:

  • Formulate specific research questions or highlight key issues you want to address through the case study.

5. Choose the Research Method:

  • Decide on the case study method or approach for data collection. A case study research method could involve qualitative methods such as interviews, observations, or document analysis.

6. Develop Data Collection Plan:

  • Outline a detailed plan for collecting data. Specify sources, methods, and tools you will use to gather relevant information.

Develop Data Collection Plan

7. Data Collection:

  • Execute the data collection plan. Conduct interviews , observe events, and analyze documents to accumulate necessary data.

8. Data Analysis:

  • Apply appropriate analytical techniques to interpret the gathered data. This may involve coding, categorizing, and identifying patterns or themes.

9. Construct the Case Study Narrative:

  • Organize the findings into a coherent and structured narrative. Develop sections that cover the introduction, background, analysis, and conclusion.

Construct the Case Study Narrative

10. Draw Conclusions:

  • Based on your analysis, after you conduct case study , draw conclusions that address the research questions or objectives. Consider the implications of your findings.

11. Peer Review or Feedback:

  • Seek feedback from colleagues, mentors, or peers to ensure the validity and reliability of your case study.

12. Finalize the Case Study:

  • Incorporate feedback and make necessary revisions. Finalize the case study, ensuring clarity, coherence, and adherence to ethical guidelines.

13. Document and Share:

  • Prepare the case study for publication or presentation and take advantage of Decktopus AI, a user-friendly and efficient presentation generator powered by AI. Easily convert your case study insights into a visually compelling deck.

Decktopus AI

  • Decktopus ensures your case studies are presented in a format that engages your audience, making your narratives more impactful and memorable. Explore the benefits of Decktopus AI to elevate your case study presentations effortlessly.

What are the Components of a Case Study

The format of a case study typically comprises several key components to present information in a structured and comprehensive manner. While variations may exist based on the context and purpose, a standard case study format often includes the following elements:

1. Introduction:

Provide a brief overview of the case and set the stage for the reader. Outline the main objectives and establish the context of the study.

introduction

2. Background:

Present relevant background information about the subject of the case. This may include the history, industry context, or any pertinent details necessary for understanding the situation.

Background

3. Problem Statement or Objectives:

Clearly state the problem or the main objectives of the case study. Define the issues or challenges that the study aims to address.

Problem Statement or Objectives

4. Analysis:

Dive into the analysis of the case. This section often comprises multiple sub-sections, each exploring different aspects such as market conditions, internal factors, external influences, etc.

data

5. Solution or Action:

Propose solutions or actions to address the identified problems. Detail the steps taken or recommended strategies based on the analysis.

solution

6. Results:

Present the outcomes of the solutions or actions taken. Include any measurable results, impacts, or changes observed.

result

7. Conclusion:

Summarize the key points, outcomes, and lessons learned. Revisit the problem statement and emphasize the significance of the study, highlighting how the research design shaped the results.

conclusion

Types of Case Studies

Case study examples, 1. marketing case study template.

marketing case study

The Marketing Case Study Template is tailored for marketers, highlighting successful marketing strategies . Uncover the methods employed, target audience engagement, and measurable outcomes.

Ideal for marketing professionals seeking insights into effective campaign executions. With Decktopus AI , spending your precious time perpetually recreating your product's presentation has become an ancient practice.

Along with our collection of case-study templates, with our one-click platform, you can easily create beautiful presentations for yourself or your clients.

Also check out: creative marketing case study template .

2. Sales Case Study Template

 Sales Case Study Template

The Sales Case Study Template is designed for salespeople to present and discuss case studies in sales meetings. With its professional look and engaging layout, your clients will be impressed with the level of detail you put into your analysis.

This professionally designed template is easy to use and easy to customize, making it the perfect way to show off your small business expertise.

So whether you're looking to wow potential clients or just need a little more confidence in your sales meetings, our client case study template will help you make an impact.

Also check-out: case study template for sales teams .

3. Design Case Study Example: UI Case Study Template

ui case

The UI Case Study Template is specifically designed for UI designers, making it easy to discuss your design process and findings. Present your design case studies like a pro with our target-spesific case study templates. With our design case study template , you'll be able to showcase your work in a clear, professional manner.

Looking to create a stunning case study presentation for your next client meeting? Look no further than our case study templates! Our professional and easy-to-use templates are perfect for designers of all experience levels, and will help you showcase your work in a clear and concise way.

Also check out: Art Case Study Template .

Explore More Case Study Templates

Case Study Templates

Discover a vast collection of case study templates from various fields, including marketing, sales, and design, in our dedicated Case Study Examples Blog. Gain insights into diverse business scenarios and find inspiration for your own projects.

Case Study Presentation Creation with Decktopus AI

Streamlining the creation of engaging visual case studies has never been easier than with Decktopus AI . This innovative platform offers a seamless experiencensimply write your input, and Decktopus takes care of the rest, ensuring that your templates not only boast a polished visual appeal but also integrate relevant and impactful content effortlessly.

Discover how easy it is to create engaging case study templates using Decktopus AI . Our platform ensures your templates look great and contain relevant content. With the help of our AI assistant, you not only get support during presentations but also receive tips, facilitate Q&A, and increase overall engagement.

Explore the unique storytelling format that Decktopus offers, making your case studies more relatable. For a step-by-guide on how to easily create a visually stunning case study with Decktopus, see our case study examples blog.

Decktopus AI

This approach allows you to present information in a narrative style, connecting better with your audience. Find practical tips for smoother case study presentations, from effective storytelling to engaging your audience. Improve your presentation experience with Decktopus AI , where simplicity meets interactivity and storytelling for effective communication.

It features, practical design, mobilizing easy principles of marketing ecosystem platform design. Making it by far the easiest thing to use in your daily practice of mobilizing marketing ecosystems through platform strategies.

Frequently Asked Questions

1) what is a marketing case study.

A marketing case study is a concise analysis of a business's marketing strategy, showcasing its objectives, challenges, tactics, and outcomes. It offers practical insights into real-world marketing applications, serving as a valuable learning tool for understanding successful practices and lessons learned in achieving specific marketing goals.

2) What is a case study?

A case study, or case report, is a concise examination of a specific subject, often real-world situations or problems, providing detailed insights and analysis for learning or decision-making purposes.

3) How should you write a case study?

To create an impactful case study, define objectives, choose a relevant case, gather key information, and use Decktopus for a polished presentation. Employ data analysis, construct a clear narrative, and offer actionable recommendations.

Validate findings and consider broader implications. Decktopus streamlines this process, providing a user-friendly platform for creating compelling case study presentations effortlessly.

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psychology

Psychology Case Study Examples: A Deep Dive into Real-life Scenarios

Psychology Case Study Examples

Peeling back the layers of the human mind is no easy task, but psychology case studies can help us do just that. Through these detailed analyses, we’re able to gain a deeper understanding of human behavior, emotions, and cognitive processes. I’ve always found it fascinating how a single person’s experience can shed light on broader psychological principles.

Over the years, psychologists have conducted numerous case studies—each with their own unique insights and implications. These investigations range from Phineas Gage’s accidental lobotomy to Genie Wiley’s tragic tale of isolation. Such examples not only enlighten us about specific disorders or occurrences but also continue to shape our overall understanding of psychology .

As we delve into some noteworthy examples , I assure you’ll appreciate how varied and intricate the field of psychology truly is. Whether you’re a budding psychologist or simply an eager learner, brace yourself for an intriguing exploration into the intricacies of the human psyche.

Understanding Psychology Case Studies

Diving headfirst into the world of psychology, it’s easy to come upon a valuable tool used by psychologists and researchers alike – case studies. I’m here to shed some light on these fascinating tools.

Psychology case studies, for those unfamiliar with them, are in-depth investigations carried out to gain a profound understanding of the subject – whether it’s an individual, group or phenomenon. They’re powerful because they provide detailed insights that other research methods might miss.

Let me share a few examples to clarify this concept further:

  • One notable example is Freud’s study on Little Hans. This case study explored a 5-year-old boy’s fear of horses and related it back to Freud’s theories about psychosexual stages.
  • Another classic example is Genie Wiley (a pseudonym), a feral child who was subjected to severe social isolation during her early years. Her heartbreaking story provided invaluable insights into language acquisition and critical periods in development.

You see, what sets psychology case studies apart is their focus on the ‘why’ and ‘how’. While surveys or experiments might tell us ‘what’, they often don’t dig deep enough into the inner workings behind human behavior.

It’s important though not to take these psychology case studies at face value. As enlightening as they can be, we must remember that they usually focus on one specific instance or individual. Thus, generalizing findings from single-case studies should be done cautiously.

To illustrate my point using numbers: let’s say we have 1 million people suffering from condition X worldwide; if only 20 unique cases have been studied so far (which would be quite typical for rare conditions), then our understanding is based on just 0.002% of the total cases! That’s why multiple sources and types of research are vital when trying to understand complex psychological phenomena fully.

In the grand scheme of things, psychology case studies are just one piece of the puzzle – albeit an essential one. They provide rich, detailed data that can form the foundation for further research and understanding. As we delve deeper into this fascinating field, it’s crucial to appreciate all the tools at our disposal – from surveys and experiments to these insightful case studies.

Importance of Case Studies in Psychology

I’ve always been fascinated by the human mind, and if you’re here, I bet you are too. Let’s dive right into why case studies play such a pivotal role in psychology.

One of the key reasons they matter so much is because they provide detailed insights into specific psychological phenomena. Unlike other research methods that might use large samples but only offer surface-level findings, case studies allow us to study complex behaviors, disorders, and even treatments at an intimate level. They often serve as a catalyst for new theories or help refine existing ones.

To illustrate this point, let’s look at one of psychology’s most famous case studies – Phineas Gage. He was a railroad construction foreman who survived a severe brain injury when an iron rod shot through his skull during an explosion in 1848. The dramatic personality changes he experienced after his accident led to significant advancements in our understanding of the brain’s role in personality and behavior.

Moreover, it’s worth noting that some rare conditions can only be studied through individual cases due to their uncommon nature. For instance, consider Genie Wiley – a girl discovered at age 13 having spent most of her life locked away from society by her parents. Her tragic story gave psychologists valuable insights into language acquisition and critical periods for learning.

Finally yet importantly, case studies also have practical applications for clinicians and therapists. Studying real-life examples can inform treatment plans and provide guidance on how theoretical concepts might apply to actual client situations.

  • Detailed insights: Case studies offer comprehensive views on specific psychological phenomena.
  • Catalyst for new theories: Real-life scenarios help shape our understanding of psychology .
  • Study rare conditions: Unique cases can offer invaluable lessons about uncommon disorders.
  • Practical applications: Clinicians benefit from studying real-world examples.

In short (but without wrapping up), it’s clear that case studies hold immense value within psychology – they illuminate what textbooks often can’t, offering a more nuanced understanding of human behavior.

Different Types of Psychology Case Studies

Diving headfirst into the world of psychology, I can’t help but be fascinated by the myriad types of case studies that revolve around this subject. Let’s take a closer look at some of them.

Firstly, we’ve got what’s known as ‘Explanatory Case Studies’. These are often used when a researcher wants to clarify complex phenomena or concepts. For example, a psychologist might use an explanatory case study to explore the reasons behind aggressive behavior in children.

Second on our list are ‘Exploratory Case Studies’, typically utilized when new and unexplored areas of research come up. They’re like pioneers; they pave the way for future studies. In psychological terms, exploratory case studies could be conducted to investigate emerging mental health conditions or under-researched therapeutic approaches.

Next up are ‘Descriptive Case Studies’. As the name suggests, these focus on depicting comprehensive and detailed profiles about a particular individual, group, or event within its natural context. A well-known example would be Sigmund Freud’s analysis of “Anna O”, which provided unique insights into hysteria.

Then there are ‘Intrinsic Case Studies’, which delve deep into one specific case because it is intrinsically interesting or unique in some way. It’s sorta like shining a spotlight onto an exceptional phenomenon. An instance would be studying savants—individuals with extraordinary abilities despite significant mental disabilities.

Lastly, we have ‘Instrumental Case Studies’. These aren’t focused on understanding a particular case per se but use it as an instrument to understand something else altogether—a bit like using one puzzle piece to make sense of the whole picture!

So there you have it! From explanatory to instrumental, each type serves its own unique purpose and adds another intriguing layer to our understanding of human behavior and cognition.

Exploring Real-Life Psychology Case Study Examples

Let’s roll up our sleeves and delve into some real-life psychology case study examples. By digging deep, we can glean valuable insights from these studies that have significantly contributed to our understanding of human behavior and mental processes.

First off, let me share the fascinating case of Phineas Gage. This gentleman was a 19th-century railroad construction foreman who survived an accident where a large iron rod was accidentally driven through his skull, damaging his frontal lobes. Astonishingly, he could walk and talk immediately after the accident but underwent dramatic personality changes, becoming impulsive and irresponsible. This case is often referenced in discussions about brain injury and personality change.

Next on my list is Genie Wiley’s heart-wrenching story. She was a victim of severe abuse and neglect resulting in her being socially isolated until she was 13 years old. Due to this horrific experience, Genie couldn’t acquire language skills typically as other children would do during their developmental stages. Her tragic story offers invaluable insight into the critical periods for language development in children.

Then there’s ‘Little Hans’, a classic Freudian case that delves into child psychology. At just five years old, Little Hans developed an irrational fear of horses -or so it seemed- which Sigmund Freud interpreted as symbolic anxiety stemming from suppressed sexual desires towards his mother—quite an interpretation! The study gave us Freud’s Oedipus Complex theory.

Lastly, I’d like to mention Patient H.M., an individual who became amnesiac following surgery to control seizures by removing parts of his hippocampus bilaterally. His inability to form new memories post-operation shed light on how different areas of our brains contribute to memory formation.

Each one of these real-life psychology case studies gives us a unique window into understanding complex human behaviors better – whether it’s dissecting the role our brain plays in shaping personality or unraveling the mysteries of fear, language acquisition, and memory.

How to Analyze a Psychology Case Study

Diving headfirst into a psychology case study, I understand it can seem like an intimidating task. But don’t worry, I’m here to guide you through the process.

First off, it’s essential to go through the case study thoroughly. Read it multiple times if needed. Each reading will likely reveal new information or perspectives you may have missed initially. Look out for any patterns or inconsistencies in the subject’s behavior and make note of them.

Next on your agenda should be understanding the theoretical frameworks that might be applicable in this scenario. Is there a cognitive-behavioral approach at play? Or does psychoanalysis provide better insights? Comparing these theories with observed behavior and symptoms can help shed light on underlying psychological issues.

Now, let’s talk data interpretation. If your case study includes raw data like surveys or diagnostic tests results, you’ll need to analyze them carefully. Here are some steps that could help:

  • Identify what each piece of data represents
  • Look for correlations between different pieces of data
  • Compute statistics (mean, median, mode) if necessary
  • Use graphs or charts for visual representation

Keep in mind; interpreting raw data requires both statistical knowledge and intuition about human behavior.

Finally, drafting conclusions is key in analyzing a psychology case study. Based on your observations, evaluations of theoretical approaches and interpretations of any given data – what do you conclude about the subject’s mental health status? Remember not to jump to conclusions hastily but instead base them solidly on evidence from your analysis.

In all this journey of analysis remember one thing: every person is unique and so are their experiences! So while theories and previous studies guide us, they never define an individual completely.

Applying Lessons from Psychology Case Studies

Let’s dive into how we can apply the lessons learned from psychology case studies. If you’ve ever studied psychology, you’ll know that case studies offer rich insights. They shed light on human behavior, mental health issues, and therapeutic techniques. But it’s not just about understanding theory. It’s also about implementing these valuable lessons in real-world situations.

One of the most famous psychological case studies is Phineas Gage’s story. This 19th-century railroad worker survived a severe brain injury which dramatically altered his personality. From this study, we gained crucial insight into how different brain areas are responsible for various aspects of our personality and behavior.

  • Lesson: Recognizing that damage to specific brain areas can result in personality changes, enabling us to better understand certain mental conditions.

Sigmund Freud’s work with a patient known as ‘Anna O.’ is another landmark psychology case study. Anna displayed what was then called hysteria – symptoms included hallucinations and disturbances in speech and physical coordination – which Freud linked back to repressed memories of traumatic events.

  • Lesson: The importance of exploring an individual’s history for understanding their current psychological problems – a principle at the heart of psychoanalysis.

Then there’s Genie Wiley’s case – a girl who suffered extreme neglect resulting in impaired social and linguistic development. Researchers used her tragic circumstances as an opportunity to explore theories around language acquisition and socialization.

  • Lesson: Reinforcing the critical role early childhood experiences play in shaping cognitive development.

Lastly, let’s consider the Stanford Prison Experiment led by Philip Zimbardo examining how people conform to societal roles even when they lead to immoral actions.

  • Lesson: Highlighting that situational forces can drastically impact human behavior beyond personal characteristics or morality.

These examples demonstrate that psychology case studies aren’t just academic exercises isolated from daily life. Instead, they provide profound lessons that help us make sense of complex human behaviors, mental health issues, and therapeutic strategies. By understanding these studies, we’re better equipped to apply their lessons in our own lives – whether it’s navigating personal relationships, working with diverse teams at work or even self-improvement.

Challenges and Critiques of Psychological Case Studies

Delving into the world of psychological case studies, it’s not all rosy. Sure, they offer an in-depth understanding of individual behavior and mental processes. Yet, they’re not without their share of challenges and criticisms.

One common critique is the lack of generalizability. Each case study is unique to its subject. We can’t always apply what we learn from one person to everyone else. I’ve come across instances where results varied dramatically between similar subjects, highlighting the inherent unpredictability in human behavior.

Another challenge lies within ethical boundaries. Often, sensitive information surfaces during these studies that could potentially harm the subject if disclosed improperly. To put it plainly, maintaining confidentiality while delivering a comprehensive account isn’t always easy.

Distortion due to subjective interpretations also poses substantial difficulties for psychologists conducting case studies. The researcher’s own bias may color their observations and conclusions – leading to skewed outcomes or misleading findings.

Moreover, there’s an ongoing debate about the scientific validity of case studies because they rely heavily on qualitative data rather than quantitative analysis. Some argue this makes them less reliable or objective when compared with other research methods such as experiments or surveys.

To summarize:

  • Lack of generalizability
  • Ethical dilemmas concerning privacy
  • Potential distortion through subjective interpretation
  • Questions about scientific validity

While these critiques present significant challenges, they do not diminish the value that psychological case studies bring to our understanding of human behavior and mental health struggles.

Conclusion: The Impact of Case Studies in Understanding Human Behavior

Case studies play a pivotal role in shedding light on human behavior. Throughout this article, I’ve discussed numerous examples that illustrate just how powerful these studies can be. Yet it’s the impact they have on our understanding of human psychology where their true value lies.

Take for instance the iconic study of Phineas Gage. It was through his tragic accident and subsequent personality change that we began to grasp the profound influence our frontal lobes have on our behavior. Without such a case study, we might still be in the dark about this crucial aspect of our neurology.

Let’s also consider Genie, the feral child who showed us the critical importance of social interaction during early development. Her heartbreaking story underscores just how vital appropriate nurturing is for healthy mental and emotional growth.

Here are some key takeaways from these case studies:

  • Our brain structure significantly influences our behavior.
  • Social interaction during formative years is vital for normal psychological development.
  • Studying individual cases can reveal universal truths about human nature.

What stands out though, is not merely what these case studies teach us individually but collectively. They remind us that each person constitutes a unique combination of various factors—biological, psychological, and environmental—that shape their behavior.

One cannot overstate the significance of case studies in psychology—they are more than mere stories or isolated incidents; they’re windows into the complexities and nuances of human nature itself.

In wrapping up, I’d say that while statistics give us patterns and trends to understand groups, it’s these detailed narratives offered by case studies that help us comprehend individuals’ unique experiences within those groups—making them an invaluable part of psychological research.

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Writing A Case Study

Case Study Examples

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Brilliant Case Study Examples and Templates For Your Help

15 min read

Case Study Examples

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A Complete Case Study Writing Guide With Examples

Simple Case Study Format for Students to Follow

Understand the Types of Case Study Here

It’s no surprise that writing a case study is one of the most challenging academic tasks for students. You’re definitely not alone here!

Most people don't realize that there are specific guidelines to follow when writing a case study. If you don't know where to start, it's easy to get overwhelmed and give up before you even begin.

Don't worry! Let us help you out!

We've collected over 25 free case study examples with solutions just for you. These samples with solutions will help you win over your panel and score high marks on your case studies.

So, what are you waiting for? Let's dive in and learn the secrets to writing a successful case study.

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  • 1. An Overview of Case Studies
  • 2. Case Study Examples for Students
  • 3. Business Case Study Examples
  • 4. Medical Case Study Examples
  • 5. Psychology Case Study Examples 
  • 6. Sales Case Study Examples
  • 7. Interview Case Study Examples
  • 8. Marketing Case Study Examples
  • 9. Tips to Write a Good Case Study

An Overview of Case Studies

A case study is a research method used to study a particular individual, group, or situation in depth. It involves analyzing and interpreting data from a variety of sources to gain insight into the subject being studied. 

Case studies are often used in psychology, business, and education to explore complicated problems and find solutions. They usually have detailed descriptions of the subject, background info, and an analysis of the main issues.

The goal of a case study is to provide a comprehensive understanding of the subject. Typically, case studies can be divided into three parts, challenges, solutions, and results. 

Here is a case study sample PDF so you can have a clearer understanding of what a case study actually is:

Case Study Sample PDF

How to Write a Case Study Examples

Learn how to write a case study with the help of our comprehensive case study guide.

Case Study Examples for Students

Quite often, students are asked to present case studies in their academic journeys. The reason instructors assign case studies is for students to sharpen their critical analysis skills, understand how companies make profits, etc.

Below are some case study examples in research, suitable for students:

Case Study Example in Software Engineering

Qualitative Research Case Study Sample

Software Quality Assurance Case Study

Social Work Case Study Example

Ethical Case Study

Case Study Example PDF

These examples can guide you on how to structure and format your own case studies.

Struggling with formatting your case study? Check this case study format guide and perfect your document’s structure today.

Business Case Study Examples

A business case study examines a business’s specific challenge or goal and how it should be solved. Business case studies usually focus on several details related to the initial challenge and proposed solution. 

To help you out, here are some samples so you can create case studies that are related to businesses: 

Here are some more business case study examples:

Business Case Studies PDF

Business Case Studies Example

Typically, a business case study discovers one of your customer's stories and how you solved a problem for them. It allows your prospects to see how your solutions address their needs. 

Medical Case Study Examples

Medical case studies are an essential part of medical education. They help students to understand how to diagnose and treat patients. 

Here are some medical case study examples to help you.

Medical Case Study Example

Nursing Case Study Example

Want to understand the various types of case studies? Check out our types of case study blog to select the perfect type.

Psychology Case Study Examples 

Case studies are a great way of investigating individuals with psychological abnormalities. This is why it is a very common assignment in psychology courses. 

By examining all the aspects of your subject’s life, you discover the possible causes of exhibiting such behavior. 

For your help, here are some interesting psychology case study examples:

Psychology Case Study Example

Mental Health Case Study Example

Sales Case Study Examples

Case studies are important tools for sales teams’ performance improvement. By examining sales successes, teams can gain insights into effective strategies and create action plans to employ similar tactics.

By researching case studies of successful sales campaigns, sales teams can more accurately identify challenges and develop solutions.

Sales Case Study Example

Interview Case Study Examples

Interview case studies provide businesses with invaluable information. This data allows them to make informed decisions related to certain markets or subjects.

Interview Case Study Example

Marketing Case Study Examples

Marketing case studies are real-life stories that showcase how a business solves a problem. They typically discuss how a business achieves a goal using a specific marketing strategy or tactic.

They typically describe a challenge faced by a business, the solution implemented, and the results achieved.

This is a short sample marketing case study for you to get an idea of what an actual marketing case study looks like.

 Here are some more popular marketing studies that show how companies use case studies as a means of marketing and promotion:

“Chevrolet Discover the Unexpected” by Carol H. Williams

This case study explores Chevrolet's “ DTU Journalism Fellows ” program. The case study uses the initials “DTU” to generate interest and encourage readers to learn more. 

Multiple types of media, such as images and videos, are used to explain the challenges faced. The case study concludes with an overview of the achievements that were met.

Key points from the case study include:

  • Using a well-known brand name in the title can create interest.
  • Combining different media types, such as headings, images, and videos, can help engage readers and make the content more memorable.
  • Providing a summary of the key achievements at the end of the case study can help readers better understand the project's impact.

“The Met” by Fantasy

“ The Met ” by Fantasy is a fictional redesign of the Metropolitan Museum of Art in New York City, created by the design studio Fantasy. The case study clearly and simply showcases the museum's website redesign.

The Met emphasizes the website’s features and interface by showcasing each section of the interface individually, allowing the readers to concentrate on the significant elements.

For those who prefer text, each feature includes an objective description. The case study also includes a “Contact Us” call-to-action at the bottom of the page, inviting visitors to contact the company.

Key points from this “The Met” include:

  • Keeping the case study simple and clean can help readers focus on the most important aspects.
  • Presenting the features and solutions with a visual showcase can be more effective than writing a lot of text.
  • Including a clear call-to-action at the end of the case study can encourage visitors to contact the company for more information.

“Better Experiences for All” by Herman Miller

Herman Miller's minimalist approach to furniture design translates to their case study, “ Better Experiences for All ”, for a Dubai hospital. The page features a captivating video with closed-captioning and expandable text for accessibility.

The case study presents a wealth of information in a concise format, enabling users to grasp the complexities of the strategy with ease. It concludes with a client testimonial and a list of furniture items purchased from the brand.

Key points from the “Better Experiences” include:

  • Make sure your case study is user-friendly by including accessibility features like closed captioning and expandable text.
  • Include a list of products that were used in the project to guide potential customers.

“NetApp” by Evisort 

Evisort's case study on “ NetApp ” stands out for its informative and compelling approach. The study begins with a client-centric overview of NetApp, strategically directing attention to the client rather than the company or team involved.

The case study incorporates client quotes and explores NetApp’s challenges during COVID-19. Evisort showcases its value as a client partner by showing how its services supported NetApp through difficult times. 

  • Provide an overview of the company in the client’s words, and put focus on the customer. 
  • Highlight how your services can help clients during challenging times.
  • Make your case study accessible by providing it in various formats.

“Red Sox Season Campaign,” by CTP Boston

The “ Red Sox Season Campaign ” showcases a perfect blend of different media, such as video, text, and images. Upon visiting the page, the video plays automatically, there are videos of Red Sox players, their images, and print ads that can be enlarged with a click.

The page features an intuitive design and invites viewers to appreciate CTP's well-rounded campaign for Boston's beloved baseball team. There’s also a CTA that prompts viewers to learn how CTP can create a similar campaign for their brand.

Some key points to take away from the “Red Sox Season Campaign”: 

  • Including a variety of media such as video, images, and text can make your case study more engaging and compelling.
  • Include a call-to-action at the end of your study that encourages viewers to take the next step towards becoming a customer or prospect.

“Airbnb + Zendesk” by Zendesk

The case study by Zendesk, titled “ Airbnb + Zendesk : Building a powerful solution together,” showcases a true partnership between Airbnb and Zendesk. 

The article begins with an intriguing opening statement, “Halfway around the globe is a place to stay with your name on it. At least for a weekend,” and uses stunning images of beautiful Airbnb locations to captivate readers.

Instead of solely highlighting Zendesk's product, the case study is crafted to tell a good story and highlight Airbnb's service in detail. This strategy makes the case study more authentic and relatable.

Some key points to take away from this case study are:

  • Use client's offerings' images rather than just screenshots of your own product or service.
  • To begin the case study, it is recommended to include a distinct CTA. For instance, Zendesk presents two alternatives, namely to initiate a trial or seek a solution.

“Influencer Marketing” by Trend and WarbyParker

The case study "Influencer Marketing" by Trend and Warby Parker highlights the potential of influencer content marketing, even when working with a limited budget. 

The “Wearing Warby” campaign involved influencers wearing Warby Parker glasses during their daily activities, providing a glimpse of the brand's products in use. 

This strategy enhanced the brand's relatability with influencers' followers. While not detailing specific tactics, the case study effectively illustrates the impact of third-person case studies in showcasing campaign results.

Key points to take away from this case study are:

  • Influencer marketing can be effective even with a limited budget.
  • Showcasing products being used in everyday life can make a brand more approachable and relatable.
  • Third-person case studies can be useful in highlighting the success of a campaign.

Marketing Case Study Example

Marketing Case Study Template

Now that you have read multiple case study examples, hop on to our tips.

Tips to Write a Good Case Study

Here are some note-worthy tips to craft a winning case study 

  • Define the purpose of the case study This will help you to focus on the most important aspects of the case. The case study objective helps to ensure that your finished product is concise and to the point.
  • Choose a real-life example. One of the best ways to write a successful case study is to choose a real-life example. This will give your readers a chance to see how the concepts apply in a real-world setting.
  • Keep it brief. This means that you should only include information that is directly relevant to your topic and avoid adding unnecessary details.
  • Use strong evidence. To make your case study convincing, you will need to use strong evidence. This can include statistics, data from research studies, or quotes from experts in the field.
  • Edit and proofread your work. Before you submit your case study, be sure to edit and proofread your work carefully. This will help to ensure that there are no errors and that your paper is clear and concise.

There you go!

We’re sure that now you have secrets to writing a great case study at your fingertips! This blog teaches the key guidelines of various case studies with samples. So grab your pen and start crafting a winning case study right away!

Having said that, we do understand that some of you might be having a hard time writing compelling case studies.

But worry not! Our expert case study writing service is here to take all your case-writing blues away! 

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Case Study

Core values case study: how we built an award-winning team

By Nick Butler

Tags : Other

The Boost Team picnic to celebrate our Team Gold win and the core values this reflected.

Find out how clarifying, cementing and celebrating our core values has allowed Boost to build an award-winning team that has continued to thrive even under COVID-19 lockdown.

Core values in context

The core values initiative that this case study looks at is part of a wider drive to create a team unified behind a common purpose and priorities.

We’re following the work of people like Patrick Lencioni and Jim Collins, who have analysed what makes organisations successful in books such as Lencioni’s The Advantage and Built to Last by Jim Collins and Jerry I. Porras. (For a quick introduction to their ideas, you can check out articles like Make Your Values Mean Something by Patrick Lencioni and Building Companies to Last by Jim Collins.)

Clarity of vision

Both Lencioni and Collins stress the importance of having a clear vision of what matters to your organisation.

Everyone needs to know where you are going and how you’ll get there.

With everyone pushing in the same direction, you reinforce your progress as you go, building ever greater momentum.

In Patrick Lencioni’s Advantage model , you get this clarity by answering six questions:

  • Why do we exist?
  • How do we behave?
  • What do we do?
  • How will we succeed?
  • What is most important, right now?
  • Who must do what?

For Jim Collins, values sit within a Vision framework :

  • Core purpose
  • Core values
  • A big, hairy, audacious goal (BHAG)
  • Vivid descriptions that bring the envisioned future to life

Purpose and goals: Where we are going

At Boost, our purpose is:

Supporting others to create positive and lasting impacts

Our goals are set out in our roadmap for the future: Boost 2026 . This gives us targets that will maximise our ability to achieve our purpose.

Core values: How we’ll get there

Our purpose and goals point us all in the same direction and our core values ensure we get there in lockstep.

Jim Collins and Jerry Porras describe core values as the essential and enduring tenets of an organisation. “A small set of timeless guiding principles, core values require no external justification; they have intrinsic value and importance within the organization.”

For Patrick Lencioni values are the behavioural traits that are inherent in an organisation. “Core values lie at the heart of the organization’s identity, do not change over time, and must already exist.”

So, your core values describe what you are, not what you want to be, or what you think will work.

Boost’s core values initiative

Here’s how we created clarity around our core values, then reinforced them so they are embedded in the way we work.

Boost already had a set of values:

  • Speed without compromise
  • Be transparent
  • Always collaborate
  • Make it safe
  • Making New Zealand a better place

But when we reviewed these, we felt they were not the best description of the values that the team demonstrated in their day-to-day work.

Creating clarity

The first step in clarifying our core values was to go back to the behaviours that demonstrate the values. What were the positive ways the team behaved with each other and with clients? And what past behaviours had created frictions that showed they ran counter to our shared values?

Our leadership team used the trusty affinity mapping process to move from behaviours to values. Working silently, they wrote down each behaviour they’d seen on a post-it. Once everyone had finished noting behaviours, they stuck the post-its on a whiteboard, reading them out and clarifying as required. Next, they grouped like with like. Once the groupings were clear, they were given a label that summed up the core value the behaviours represented.

The next step was to craft descriptions of the core values based on the behaviours. These descriptions needed to be authentic, relatable and concrete.

Ensuring authenticity

We then shared the draft values with the wider team for feedback.

This started with a whole-team meeting. Our CEO explained what core values are and what they aren’t, why Boost wants to be clear about them, and why we were revisiting them. We then discussed the values the leadership team had come up with.

These were then posted prominently on the wall with a space for feedback, suggestions and questions.

Once the whole team had had a chance to have input into the values, we shared the final versions, adding them to the handbook that all Boosters receive.

Boost’s core values

Responsibility | Haepapatanga : We have a responsibility to have an economically successful organisation to ensure stability and opportunities for team members, stakeholders and clients. We take responsibility for our customers’ outcomes. We are in charge of our own learning and sharing knowledge with the wider team.

Servant leadership | Rangatiratanga manukura :  We are all leaders and at Boost, all leaders serve. We are focussed on what we can do for others and developing our teams. We balance the needs of the individual with those of the organisation. We listen. We coach, we are humble and trusting. We value service not status.

Courage | Te hopo whitia : We have thoughtful opinions but hold them lightly. We are at our best when we embrace constructive conflict and commit to being authentic and vulnerable. Feedback is a gift to give and receive, we lean into difficult conversations. Be brave and give it a go.

Manaakitanga : We make everyone feel welcome. We create an environment where everyone can be successful; we nurture relationships, raise others up and work to create and maintain safe spaces.

You can read the translator’s commentary on how he came up with the reo versions of our values in our post on Using te reo in the workplace .

Reinforcing our core values

Now we’d identified our shared values, we needed to reinforce them to harness the strength that comes from common principles and priorities. According to Patrick Lencioni values aren’t just something you communicate, they’re something you over-communicate.

The Values Awards

Every month, the team gets together for a Values Awards ceremony.

At the ceremony, four people are presented with a medallion, one for each of our values. As each award is presented, we explain the specific way each winner has demonstrated the value. Winners also get a certificate explaining why they’ve won the award and a value sticker for their laptop cover, so they can collect all four.

The Awards embed the values in the rhythm of our work. They further clarify the values by showing what they look like in practice. Being reminded of the ways our colleagues embody our common values brings the team together and reinforces the values. Because the previous winners choose the next recipients, they consider and discuss what the values mean to them, which makes the values more relevant and real.

Reinforcing through recruitment

We use our recruitment process to reinforce our core values in two main ways.

  • We only recruit people aligned with our purpose and values.

Our interviews include questions designed to identify what’s important to applicants, what it is they value in their work and their working relationships.

  • The way we recruit demonstrates our values.

For example, the wider team demonstrates Responsibility by interviewing applicants and running technical challenges, and Manaakitanga by looking after applicants when they spend a meet-the-team day at Boost and by buddying-up with new Boosters during onboarding.

Reinforcing empowerment

For nine years now, Boost has been Worldblu-certified as a freedom-centred workplace. The values of Responsibility, Servant leadership, Courage and Manaakitanga both flow from and reinforce our culture of empowerment.

Our Boost 2026 goals embed these values and this culture. Along with growing the company to increase our impact, we will:

  • have co-CEOs, male and female, elected by the team
  • be 100% employee-owned.

We’re already seeing the benefits of our focus on core values.

Award-winning team culture

In 2019, we won the Team Gold Award .

This award recognises the initiatives we’ve introduced in our mission to make Boost the best place to work in New Zealand, initiatives guided and made possible by our shared values.

Measuring the value of core values

As part of our drive to make Boost the best place to work in New Zealand, we use TinyPulse to survey how happy the team is at work.

  • In the past year, our Team Happiness rating hit its highest point ever.

We are also seeing increases in our capacity to help others have a positive and lasting impact, and in our productivity. This year we have:

  • grown our team by 16%
  • increased net profit by 53%.

We survey the team to check that we are staying true to our core values (all answers are anonymous).

  • In the most recent survey, 100% agreed we stay true to our values.

Here are some of the responses:

“The values shone through even in lockdown.”

“The set of crystal clear values and ideals that every member of every team understands and lives by helps to create a culture that is consistently amazing to be a part of.”

“Even more so now with the medallions because it brings the values to the forefront and lets the whole team know who is showing our values.”

Common values help us cope with COVID-19

As with many organisations, the pandemic has been the biggest challenge of 2020. But having a team aligned behind common values meant we could stay strong and support each other while we were all working remotely. New Zealand has moved out of lockdown (for now, anyway) so we can look back at how we coped.

  • Even at the height of the crisis, our Team Happiness rating stayed well above the pre-crisis industry benchmark.
  • Feedback from clients showed we consistently maintained full productivity while working remotely during the COVID-19 lockdown. In fact, April 2020 was our biggest billing month ever.
  • Despite joining us in the middle of the lockdown, Greg Rogan described starting at Boost as “the best onboarding experience that I’ve had in any job.”

These are achievements the team at Boost are very proud of. They are a potent reminder of the power of shared values and common purpose. We hope this core values case study helps you get your own team synchronised for success.

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, .

  • Open access
  • Published: 15 May 2024

Learning together for better health using an evidence-based Learning Health System framework: a case study in stroke

  • Helena Teede 1 , 2   na1 ,
  • Dominique A. Cadilhac 3 , 4   na1 ,
  • Tara Purvis 3 ,
  • Monique F. Kilkenny 3 , 4 ,
  • Bruce C.V. Campbell 4 , 5 , 6 ,
  • Coralie English 7 ,
  • Alison Johnson 2 ,
  • Emily Callander 1 ,
  • Rohan S. Grimley 8 , 9 ,
  • Christopher Levi 10 ,
  • Sandy Middleton 11 , 12 ,
  • Kelvin Hill 13 &
  • Joanne Enticott   ORCID: orcid.org/0000-0002-4480-5690 1  

BMC Medicine volume  22 , Article number:  198 ( 2024 ) Cite this article

3 Altmetric

Metrics details

In the context of expanding digital health tools, the health system is ready for Learning Health System (LHS) models. These models, with proper governance and stakeholder engagement, enable the integration of digital infrastructure to provide feedback to all relevant parties including clinicians and consumers on performance against best practice standards, as well as fostering innovation and aligning healthcare with patient needs. The LHS literature primarily includes opinion or consensus-based frameworks and lacks validation or evidence of benefit. Our aim was to outline a rigorously codesigned, evidence-based LHS framework and present a national case study of an LHS-aligned national stroke program that has delivered clinical benefit.

Current core components of a LHS involve capturing evidence from communities and stakeholders (quadrant 1), integrating evidence from research findings (quadrant 2), leveraging evidence from data and practice (quadrant 3), and generating evidence from implementation (quadrant 4) for iterative system-level improvement. The Australian Stroke program was selected as the case study as it provides an exemplar of how an iterative LHS works in practice at a national level encompassing and integrating evidence from all four LHS quadrants. Using this case study, we demonstrate how to apply evidence-based processes to healthcare improvement and embed real-world research for optimising healthcare improvement. We emphasize the transition from research as an endpoint, to research as an enabler and a solution for impact in healthcare improvement.

Conclusions

The Australian Stroke program has nationally improved stroke care since 2007, showcasing the value of integrated LHS-aligned approaches for tangible impact on outcomes. This LHS case study is a practical example for other health conditions and settings to follow suit.

Peer Review reports

Internationally, health systems are facing a crisis, driven by an ageing population, increasing complexity, multi-morbidity, rapidly advancing health technology and rising costs that threaten sustainability and mandate transformation and improvement [ 1 , 2 ]. Although research has generated solutions to healthcare challenges, and the advent of big data and digital health holds great promise, entrenched siloes and poor integration of knowledge generation, knowledge implementation and healthcare delivery between stakeholders, curtails momentum towards, and consistent attainment of, evidence-and value-based care [ 3 ]. This is compounded by the short supply of research and innovation leadership within the healthcare sector, and poorly integrated and often inaccessible health data systems, which have crippled the potential to deliver on digital-driven innovation [ 4 ]. Current approaches to healthcare improvement are also often isolated with limited sustainability, scale-up and impact [ 5 ].

Evidence suggests that integration and partnership across academic and healthcare delivery stakeholders are key to progress, including those with lived experience and their families (referred to here as consumers and community), diverse disciplines (both research and clinical), policy makers and funders. Utilization of evidence from research and evidence from practice including data from routine care, supported by implementation research, are key to sustainably embedding improvement and optimising health care and outcomes. A strategy to achieve this integration is through the Learning Health System (LHS) (Fig.  1 ) [ 2 , 6 , 7 , 8 ]. Although there are numerous publications on LHS approaches [ 9 , 10 , 11 , 12 ], many focus on research perspectives and data, most do not demonstrate tangible healthcare improvement or better health outcomes. [ 6 ]

figure 1

Monash Learning Health System: The Learn Together for Better Health Framework developed by Monash Partners and Monash University (from Enticott et al. 2021 [ 7 ]). Four evidence quadrants: Q1 (orange) is evidence from stakeholders; Q2 (green) is evidence from research; Q3 (light blue) is evidence from data; and, Q4 (dark blue) is evidence from implementation and healthcare improvement

In developed nations, it has been estimated that 60% of care provided aligns with the evidence base, 30% is low value and 10% is potentially harmful [ 13 ]. In some areas, clinical advances have been rapid and research and evidence have paved the way for dramatic improvement in outcomes, mandating rapid implementation of evidence into healthcare (e.g. polio and COVID-19 vaccines). However, healthcare improvement is challenging and slow [ 5 ]. Health systems are highly complex in their design, networks and interacting components, and change is difficult to enact, sustain and scale up. [ 3 ] New effective strategies are needed to meet community needs and deliver evidence-based and value-based care, which reorients care from serving the provider, services and system, towards serving community needs, based on evidence and quality. It goes beyond cost to encompass patient and provider experience, quality care and outcomes, efficiency and sustainability [ 2 , 6 ].

The costs of stroke care are expected to rise rapidly in the next decades, unless improvements in stroke care to reduce the disabling effects of strokes can be successfully developed and implemented [ 14 ]. Here, we briefly describe the Monash LHS framework (Fig.  1 ) [ 2 , 6 , 7 ] and outline an exemplar case in order to demonstrate how to apply evidence-based processes to healthcare improvement and embed real-world research for optimising healthcare. The Australian LHS exemplar in stroke care has driven nationwide improvement in stroke care since 2007.

An evidence-based Learning Health System framework

In Australia, members of this author group (HT, AJ, JE) have rigorously co-developed an evidence-based LHS framework, known simply as the Monash LHS [ 7 ]. The Monash LHS was designed to support sustainable, iterative and continuous robust benefit of improved clinical outcomes. It was created with national engagement in order to be applicable to Australian settings. Through this rigorous approach, core LHS principles and components have been established (Fig.  1 ). Evidence shows that people/workforce, culture, standards, governance and resources were all key to an effective LHS [ 2 , 6 ]. Culture is vital including trust, transparency, partnership and co-design. Key processes include legally compliant data sharing, linkage and governance, resources, and infrastructure [ 4 ]. The Monash LHS integrates disparate and often siloed stakeholders, infrastructure and expertise to ‘Learn Together for Better Health’ [ 7 ] (Fig.  1 ). This integrates (i) evidence from community and stakeholders including priority areas and outcomes; (ii) evidence from research and guidelines; (iii) evidence from practice (from data) with advanced analytics and benchmarking; and (iv) evidence from implementation science and health economics. Importantly, it starts with the problem and priorities of key stakeholders including the community, health professionals and services and creates an iterative learning system to address these. The following case study was chosen as it is an exemplar of how a Monash LHS-aligned national stroke program has delivered clinical benefit.

Australian Stroke Learning Health System

Internationally, the application of LHS approaches in stroke has resulted in improved stroke care and outcomes [ 12 ]. For example, in Canada a sustained decrease in 30-day in-hospital mortality has been found commensurate with an increase in resources to establish the multifactorial stroke system intervention for stroke treatment and prevention [ 15 ]. Arguably, with rapid advances in evidence and in the context of an ageing population with high cost and care burden and substantive impacts on quality of life, stroke is an area with a need for rapid research translation into evidence-based and value-based healthcare improvement. However, a recent systematic review found that the existing literature had few comprehensive examples of LHS adoption [ 12 ]. Although healthcare improvement systems and approaches were described, less is known about patient-clinician and stakeholder engagement, governance and culture, or embedding of data informatics into everyday practice to inform and drive improvement [ 12 ]. For example, in a recent review of quality improvement collaborations, it was found that although clinical processes in stroke care are improved, their short-term nature means there is uncertainty about sustainability and impacts on patient outcomes [ 16 ]. Table  1 provides the main features of the Australian Stroke LHS based on the four core domains and eight elements of the Learning Together for Better Health Framework described in Fig.  1 . The features are further expanded on in the following sections.

Evidence from stakeholders (LHS quadrant 1, Fig.  1 )

Engagement, partners and priorities.

Within the stroke field, there have been various support mechanisms to facilitate an LHS approach including partnership and broad stakeholder engagement that includes clinical networks and policy makers from different jurisdictions. Since 2008, the Australian Stroke Coalition has been co-led by the Stroke Foundation, a charitable consumer advocacy organisation, and Stroke Society of Australasia a professional society with membership covering academics and multidisciplinary clinician networks, that are collectively working to improve stroke care ( https://australianstrokecoalition.org.au/ ). Surveys, focus groups and workshops have been used for identifying priorities from stakeholders. Recent agreed priorities have been to improve stroke care and strengthen the voice for stroke care at a national ( https://strokefoundation.org.au/ ) and international level ( https://www.world-stroke.org/news-and-blog/news/world-stroke-organization-tackle-gaps-in-access-to-quality-stroke-care ), as well as reduce duplication amongst stakeholders. This activity is built on a foundation and culture of research and innovation embedded within the stroke ‘community of practice’. Consumers, as people with lived experience of stroke are important members of the Australian Stroke Coalition, as well as representatives from different clinical colleges. Consumers also provide critical input to a range of LHS activities via the Stroke Foundation Consumer Council, Stroke Living Guidelines committees, and the Australian Stroke Clinical Registry (AuSCR) Steering Committee (described below).

Evidence from research (LHS quadrant 2, Fig.  1 )

Advancement of the evidence for stroke interventions and synthesis into clinical guidelines.

To implement best practice, it is crucial to distil the large volume of scientific and trial literature into actionable recommendations for clinicians to use in practice [ 24 ]. The first Australian clinical guidelines for acute stroke were produced in 2003 following the increasing evidence emerging for prevention interventions (e.g. carotid endarterectomy, blood pressure lowering), acute medical treatments (intravenous thrombolysis, aspirin within 48 h of ischemic stroke), and optimised hospital management (care in dedicated stroke units by a specialised and coordinated multidisciplinary team) [ 25 ]. Importantly, a number of the innovations were developed, researched and proven effective by key opinion leaders embedded in the Australian stroke care community. In 2005, the clinical guidelines for Stroke Rehabilitation and Recovery [ 26 ] were produced, with subsequent merged guidelines periodically updated. However, the traditional process of periodic guideline updates is challenging for end users when new research can render recommendations redundant and this lack of currency erodes stakeholder trust [ 27 ]. In response to this challenge the Stroke Foundation and Cochrane Australia entered a pioneering project to produce the first electronic ‘living’ guidelines globally [ 20 ]. Major shifts in the evidence for reperfusion therapies (e.g. extended time-window intravenous thrombolysis and endovascular clot retrieval), among other advances, were able to be converted into new recommendations, approved by the Australian National Health and Medical Research Council within a few months of publication. Feedback on this process confirmed the increased use and trust in the guidelines by clinicians. The process informed other living guidelines programs, including the successful COVID-19 clinical guidelines [ 28 ].

However, best practice clinical guideline recommendations are necessary but insufficient for healthcare improvement and nesting these within an LHS with stakeholder partnership, enables implementation via a range of proven methods, including audit and feedback strategies [ 29 ].

Evidence from data and practice (LHS quadrant 3, Fig.  1 )

Data systems and benchmarking : revealing the disparities in care between health services. A national system for standardized stroke data collection was established as the National Stroke Audit program in 2007 by the Stroke Foundation [ 30 ] following various state-level programs (e.g. New South Wales Audit) [ 31 ] to identify evidence-practice gaps and prioritise improvement efforts to increase access to stroke units and other acute treatments [ 32 ]. The Audit program alternates each year between acute (commencing in 2007) and rehabilitation in-patient services (commencing in 2008). The Audit program provides a ‘deep dive’ on the majority of recommendations in the clinical guidelines whereby participating hospitals provide audits of up to 40 consecutive patient medical records and respond to a survey about organizational resources to manage stroke. In 2009, the AuSCR was established to provide information on patients managed in acute hospitals based on a small subset of quality processes of care linked to benchmarked reports of performance (Fig.  2 ) [ 33 ]. In this way, the continuous collection of high-priority processes of stroke care could be regularly collected and reviewed to guide improvement to care [ 34 ]. Plus clinical quality registry programs within Australia have shown a meaningful return on investment attributed to enhanced survival, improvements in quality of life and avoided costs of treatment or hospital stay [ 35 ].

figure 2

Example performance report from the Australian Stroke Clinical Registry: average door-to-needle time in providing intravenous thrombolysis by different hospitals in 2021 [ 36 ]. Each bar in the figure represents a single hospital

The Australian Stroke Coalition endorsed the creation of an integrated technological solution for collecting data through a single portal for multiple programs in 2013. In 2015, the Stroke Foundation, AuSCR consortium, and other relevant groups cooperated to design an integrated data management platform (the Australian Stroke Data Tool) to reduce duplication of effort for hospital staff in the collection of overlapping variables in the same patients [ 19 ]. Importantly, a national data dictionary then provided the common data definitions to facilitate standardized data capture. Another important feature of AuSCR is the collection of patient-reported outcome surveys between 90 and 180 days after stroke, and annual linkage with national death records to ascertain survival status [ 33 ]. To support a LHS approach, hospitals that participate in AuSCR have access to a range of real-time performance reports. In efforts to minimize the burden of data collection in the AuSCR, interoperability approaches to import data directly from hospital or state-level managed stroke databases have been established (Fig.  3 ); however, the application has been variable and 41% of hospitals still manually enter all their data.

figure 3

Current status of automated data importing solutions in the Australian Stroke Clinical Registry, 2022, with ‘ n ’ representing the number of hospitals. AuSCR, Australian Stroke Clinical Registry; AuSDaT, Australian Stroke Data Tool; API, Application Programming Interface; ICD, International Classification of Diseases; RedCAP, Research Electronic Data Capture; eMR, electronic medical records

For acute stroke care, the Australian Commission on Quality and Safety in Health Care facilitated the co-design (clinicians, academics, consumers) and publication of the national Acute Stroke Clinical Care Standard in 2015 [ 17 ], and subsequent review [ 18 ]. The indicator set for the Acute Stroke Standard then informed the expansion of the minimum dataset for AuSCR so that hospitals could routinely track their performance. The national Audit program enabled hospitals not involved in the AuSCR to assess their performance every two years against the Acute Stroke Standard. Complementing these efforts, the Stroke Foundation, working with the sector, developed the Acute and Rehabilitation Stroke Services Frameworks to outline the principles, essential elements, models of care and staffing recommendations for stroke services ( https://informme.org.au/guidelines/national-stroke-services-frameworks ). The Frameworks are intended to guide where stroke services should be developed, and monitor their uptake with the organizational survey component of the Audit program.

Evidence from implementation and healthcare improvement (LHS quadrant 4, Fig.  1 )

Research to better utilize and augment data from registries through linkage [ 37 , 38 , 39 , 40 ] and to ensure presentation of hospital or service level data are understood by clinicians has ensured advancement in the field for the Australian Stroke LHS [ 41 ]. Importantly, greater insights into whole patient journeys, before and after a stroke, can now enable exploration of value-based care. The LHS and stroke data platform have enabled focused and time-limited projects to create a better understanding of the quality of care in acute or rehabilitation settings [ 22 , 42 , 43 ]. Within stroke, all the elements of an LHS culminate into the ready availability of benchmarked performance data and support for implementation of strategies to address gaps in care.

Implementation research to grow the evidence base for effective improvement interventions has also been a key pillar in the Australian context. These include multi-component implementation interventions to achieve behaviour change for particular aspects of stroke care, [ 22 , 23 , 44 , 45 ] and real-world approaches to augmenting access to hyperacute interventions in stroke through the use of technology and telehealth [ 46 , 47 , 48 , 49 ]. The evidence from these studies feeds into the living guidelines program and the data collection systems, such as the Audit program or AuSCR, which are then amended to ensure data aligns to recommended care. For example, the use of ‘hyperacute aspirin within the first 48 h of ischemic stroke’ was modified to be ‘hyperacute antiplatelet…’ to incorporate new evidence that other medications or combinations are appropriate to use. Additionally, new datasets have been developed to align with evidence such as the Fever, Sugar, and Swallow variables [ 42 ]. Evidence on improvements in access to best practice care from the acute Audit program [ 50 ] and AuSCR is emerging [ 36 ]. For example, between 2007 and 2017, the odds of receiving intravenous thrombolysis after ischemic stroke increased by 16% 9OR 1.06 95% CI 1.13–1.18) and being managed in a stroke unit by 18% (OR 1.18 95% CI 1.17–1.20). Over this period, the median length of hospital stay for all patients decreased from 6.3 days in 2007 to 5.0 days in 2017 [ 51 ]. When considering the number of additional patients who would receive treatment in 2017 in comparison to 2007 it was estimated that without this additional treatment, over 17,000 healthy years of life would be lost in 2017 (17,786 disability-adjusted life years) [ 51 ]. There is evidence on the cost-effectiveness of different system-focussed strategies to augment treatment access for acute ischemic stroke (e.g. Victorian Stroke Telemedicine program [ 52 ] and Melbourne Mobile Stroke Unit ambulance [ 53 ]). Reciprocally, evidence from the national Rehabilitation Audit, where the LHS approach has been less complete or embedded, has shown fewer areas of healthcare improvement over time [ 51 , 54 ].

Within the field of stroke in Australia, there is indirect evidence that the collective efforts that align to establishing the components of a LHS have had an impact. Overall, the age-standardised rate of stroke events has reduced by 27% between 2001 and 2020, from 169 to 124 events per 100,000 population. Substantial declines in mortality rates have been reported since 1980. Commensurate with national clinical guidelines being updated in 2007 and the first National Stroke Audit being undertaken in 2007, the mortality rates for men (37.4 deaths per 100,000) and women (36.1 deaths per 100,0000 has declined to 23.8 and 23.9 per 100,000, respectively in 2021 [ 55 ].

Underpinning the LHS with the integration of the four quadrants of evidence from stakeholders, research and guidelines, practice and implementation, and core LHS principles have been addressed. Leadership and governance have been important, and programs have been established to augment workforce training and capacity building in best practice professional development. Medical practitioners are able to undertake courses and mentoring through the Australasian Stroke Academy ( http://www.strokeacademy.com.au/ ) while nurses (and other health professionals) can access teaching modules in stroke care from the Acute Stroke Nurses Education Network ( https://asnen.org/ ). The Association of Neurovascular Clinicians offers distance-accessible education and certification to develop stroke expertise for interdisciplinary professionals, including advanced stroke co-ordinator certification ( www.anvc.org ). Consumer initiative interventions are also used in the design of the AuSCR Public Summary Annual reports (available at https://auscr.com.au/about/annual-reports/ ) and consumer-related resources related to the Living Guidelines ( https://enableme.org.au/resources ).

The important success factors and lessons from stroke as a national exemplar LHS in Australia include leadership, culture, workforce and resources integrated with (1) established and broad partnerships across the academic-clinical sector divide and stakeholder engagement; (2) the living guidelines program; (3) national data infrastructure, including a national data dictionary that provides the common data framework to support standardized data capture; (4) various implementation strategies including benchmarking and feedback as well as engagement strategies targeting different levels of the health system; and (5) implementation and improvement research to advance stroke systems of care and reduce unwarranted variation in practice (Fig.  1 ). Priority opportunities now include the advancement of interoperability with electronic medical records as an area all clinical quality registry’s programs needs to be addressed, as well as providing more dynamic and interactive data dashboards tailored to the need of clinicians and health service executives.

There is a clear mandate to optimise healthcare improvement with big data offering major opportunities for change. However, we have lacked the approaches to capture evidence from the community and stakeholders, to integrate evidence from research, to capture and leverage data or evidence from practice and to generate and build on evidence from implementation using iterative system-level improvement. The LHS provides this opportunity and is shown to deliver impact. Here, we have outlined the process applied to generate an evidence-based LHS and provide a leading exemplar in stroke care. This highlights the value of moving from single-focus isolated approaches/initiatives to healthcare improvement and the benefit of integration to deliver demonstrable outcomes for our funders and key stakeholders — our community. This work provides insight into strategies that can both apply evidence-based processes to healthcare improvement as well as implementing evidence-based practices into care, moving beyond research as an endpoint, to research as an enabler, underpinning delivery of better healthcare.

Availability of data and materials

Not applicable

Abbreviations

Australian Stroke Clinical Registry

Confidence interval

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Acknowledgements

The following authors hold National Health and Medical Research Council Research Fellowships: HT (#2009326), DAC (#1154273), SM (#1196352), MFK Future Leader Research Fellowship (National Heart Foundation #105737). The Funders of this work did not have any direct role in the design of the study, its execution, analyses, interpretation of the data, or decision to submit results for publication.

Author information

Helena Teede and Dominique A. Cadilhac contributed equally.

Authors and Affiliations

Monash Centre for Health Research and Implementation, 43-51 Kanooka Grove, Clayton, VIC, Australia

Helena Teede, Emily Callander & Joanne Enticott

Monash Partners Academic Health Science Centre, 43-51 Kanooka Grove, Clayton, VIC, Australia

Helena Teede & Alison Johnson

Stroke and Ageing Research, Department of Medicine, School of Clinical Sciences at Monash Health, Monash University, Level 2 Monash University Research, Victorian Heart Hospital, 631 Blackburn Rd, Clayton, VIC, Australia

Dominique A. Cadilhac, Tara Purvis & Monique F. Kilkenny

Stroke Theme, The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, VIC, Australia

Dominique A. Cadilhac, Monique F. Kilkenny & Bruce C.V. Campbell

Department of Neurology, Melbourne Brain Centre, Royal Melbourne Hospital, Parkville, VIC, Australia

Bruce C.V. Campbell

Department of Medicine, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Victoria, Australia

School of Health Sciences, Heart and Stroke Program, University of Newcastle, Hunter Medical Research Institute, University Drive, Callaghan, NSW, Australia

Coralie English

School of Medicine and Dentistry, Griffith University, Birtinya, QLD, Australia

Rohan S. Grimley

Clinical Excellence Division, Queensland Health, Brisbane, Australia

John Hunter Hospital, Hunter New England Local Health District and University of Newcastle, Sydney, NSW, Australia

Christopher Levi

School of Nursing, Midwifery and Paramedicine, Australian Catholic University, Sydney, NSW, Australia

Sandy Middleton

Nursing Research Institute, St Vincent’s Health Network Sydney and and Australian Catholic University, Sydney, NSW, Australia

Stroke Foundation, Level 7, 461 Bourke St, Melbourne, VIC, Australia

Kelvin Hill

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Contributions

HT: conception, design and initial draft, developed the theoretical formalism for learning health system framework, approved the submitted version. DAC: conception, design and initial draft, provided essential literature and case study examples, approved the submitted version. TP: revised the manuscript critically for important intellectual content, approved the submitted version. MFK: revised the manuscript critically for important intellectual content, provided essential literature and case study examples, approved the submitted version. BC: revised the manuscript critically for important intellectual content, provided essential literature and case study examples, approved the submitted version. CE: revised the manuscript critically for important intellectual content, provided essential literature and case study examples, approved the submitted version. AJ: conception, design and initial draft, developed the theoretical formalism for learning health system framework, approved the submitted version. EC: revised the manuscript critically for important intellectual content, approved the submitted version. RSG: revised the manuscript critically for important intellectual content, provided essential literature and case study examples, approved the submitted version. CL: revised the manuscript critically for important intellectual content, provided essential literature and case study examples, approved the submitted version. SM: revised the manuscript critically for important intellectual content, provided essential literature and case study examples, approved the submitted version. KH: revised the manuscript critically for important intellectual content, provided essential literature and case study examples, approved the submitted version. JE: conception, design and initial draft, developed the theoretical formalism for learning health system framework, approved the submitted version. All authors read and approved the final manuscript.

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Teede, H., Cadilhac, D.A., Purvis, T. et al. Learning together for better health using an evidence-based Learning Health System framework: a case study in stroke. BMC Med 22 , 198 (2024). https://doi.org/10.1186/s12916-024-03416-w

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DOI : https://doi.org/10.1186/s12916-024-03416-w

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EPA Transcriptomic Assessment Product (ETAP) and Value of Information (VOI) Case Study

EPA’s Safer Chemicals Research  aims to address the challenge of needing more chemical information to make informed, risk-based decisions. Less  than a quarter of the tens of thousands of chemicals in commerce--as well as those found in the environment, various waste streams, and the human body--have traditional toxicity or epidemiological data that can inform human health risk assessments. To address the challenge,  researchers developed the EPA Transcriptomic Assessment Product (ETAP). ETAP is a novel human health assessment approach targeting chemicals lacking traditional toxicity testing data. To accompany the ETAP, EPA also conducted a Value of Information (VOI) analysis to weigh the public health and economic trade-offs associated with the timeliness, uncertainty, and costs of the ETAP compared to traditional toxicity tests. 

EPA Transcriptomic Assessment Product (ETAP)

Value of information (voi) analysis.

  • Expected Results

Flow chart depicting the three main components and associated processes in developing an ETAP

A human health assessment or science assessment is typically the hazard identification and dose-response analysis that produces a reference value for the chemical. This, along with exposure information, is foundational for a risk assessment . 

One reason for the limited number of human health assessments, and subsequent risk assessments, is traditional toxicity testing and human health assessments for a chemical are time and resource intensive--often taking eight or more years to complete. State agencies, the public, and various stakeholder organizations are in need of toxicity values for data poor chemicals in a shorter timeframe in order to take an informed action to protect human health.

The draft EPA Transcriptomic Assessment Product (ETAP) aims to help address chemicals lacking traditional toxicity testing data in a more timely way. The primary driver for this new assessment product is the lack of human health toxicity values for most chemicals under the EPA regulatory purview. The ETAP transcriptomic-based reference values can be developed and reported in a 6–9-month timeframe, providing key data to the Agency that may facilitate more timely regulatory decision-making. ETAP is currently undergoing a Board of Scientific Counselors (BOSC) and public comment review. 

" Transcriptomics " is the study of messenger RNA molecules expressed in a cell or tissue, and it takes advantage of technology from the human genome project   tha t allows for a comprehensive evaluation of changes in gene activity. Previous studies have demonstrated that doses of chemicals causing disruption of gene activity are highly correlated with doses causing toxicological responses in traditional animal toxicity tests. Costs associated with the RNA sequencing technology have fallen significantly, making it more accessible and enabling broad application to environmental issues.

Read the draft reports: 

  • Standard Methods for Development of ETAPs (pdf) (3.1 MB)
  • Scientific Studies Supporting Development of Transcriptomic Points of Departure for EPA Transcriptomic Assessment Products (ETAPs) (pdf) (2.3 MB)

EPA developed a Value of Information (VOI) decision frameworks to evaluate the ETAP compared to toxicity testing in traditional human health assessments. VOI analysis was listed as a recommendation in the 2009 NAS report Science and Decisions  to provide EPA a more objective decision framework in assessing the trade-offs of time, uncertainty, and cost for a variety of chemical exposure scenarios and decision contexts.

case study values example

This socio-economic analysis compares the public health (i.e., societal health benefits) and economic trade-offs associated with the ETAP as compared to traditional toxicity testing and human health assessment.

The VOI results suggest a more timely new assessment product, like the ETAP, has significant public health and economic benefits compared with the traditional toxicity testing and human health assessment process.

Read the draft report:

  • VOI Case Study Report (pdf) (3.1 MB)
  • VOI Case Study Supplemental Material (pdf) (1.4 MB)

Results and Future Directions

The goal of the draft ETAP is to develop and operationalize a new process for timely human health assessment for chemicals that lack human health toxicity data. Once the chemical of interest is in the lab, an ETAP can be completed in less than a year. In the reports developed by the EPA for scientific peer review, a literature review and transcriptomic dose response analysis studies showed high concordance between transcriptomic and apical benchmark dose (BMD) values in traditional animal toxicity studies. The concordance was robust across species, sex, route of exposure, physical chemical properties, toxicokinetic half-life, and technology platform. The error associated with the concordance between the transcriptomic and apical BMD values was demonstrated to be approximately equivalent to the combined inter-study variability associated with the transcriptomic study and the two-year rodent bioassay. 

In July 2023,  EPA solicited public comment and held two separate ad hoc Board of Scientific Counselors (BOSC) panels met to review the ETAP and VOI materials. After these reviews, EPA will respond to comments, finalize and publish these reports. 

  • Board of Scientific Counselors (BOSC)  EPA Transcriptomic Assessment Products (ETAP) Panel
  • Board of Scientific Counselors (BOSC) Value of Information (VOI) Panel
  • Standard Methods
  • Value of Information Case Study
  • Assessments

Identify Motivation and Challenges in Data Modeling

After completing this lesson, you will be able to:

  • Identify motivation and challenges in data modeling

Motivation for Data Modeling

Difference in values.

Different sales results from different departments.

Values collected from information processing systems often drive business decisions. Therefore, numerous reports are distributed. But where do the values come from and how reliable are they?

Imagine the decision-maker asking for the total quantity that has been delivered to a specific customer, getting two different answers:

  • The storage department states that they sold 14 KG.
  • The sales department states that the company sold 15 KG.

Without a central data collection strategy, each department relies on their own calculations. If every department keeps their own, independent database, based on the same original business process, this is called a silo.

Silos are multiple copies of the same data source with different, independent steps of consolidation, harmonization, and enhancement.

The problems with silos are:

  • Misunderstandings in discussions.
  • Aggregation of errors.
  • Different beliefs about the truth and the recommended behavior.
  • Differences in values between different public reports.

Different departments show different sales results.

Why do different departments get different results? Let's look at an example with possible reasons for the differences:

  • Different database : Different source tables (such as an aggregated source table versus a details source table), different filter values, or different times, or different source systems regularly lead to different extraction results.
  • Different actuality of values : If, at an early stage, the wrong data was extracted from the source system that was corrected later. It's important to update the values in the reporting system.
  • Different times of extraction : Values in the source vary. New orders might be added, or status information may change. Then, values may differ depending on whether they're extracted in the morning or in the evening.
  • Different calculation definitions : How is a margin defined? Which costs must be distracted? Is a percentage value based on kilograms or liters?
  • Different steps of calculation : Is an aggregation over different products calculated before a unit conversion is calculated on an average conversion factor? Or is the conversion carried out with a product-specific conversion factor before values are aggregated? Is a share (percentage value) calculated before or after a unit conversion is carried out?
  • Different times of calculation : If conversion factors change, different conversion factors lead to different results.
  • No good quality management : You've no control over the reliability of the output.

Data Modeling Directive

Aspects of a data modeling directive.

Many companies decide to implement a data warehouse, such as SAP BW/4HANA, with a central storage of all enterprise information, and fast information processing.

However, even the best software solution must be accompanied by a good data modeling directive.

Aspects of a data modeling directive.

A data modeling directive is a guideline regarding what must be done: where, when, with what data, and in which way?

A data modeling directive has to address the following:

  • What business processes are in focus?
  • Are values needed for the entire enterprise, or for a local subsidiary?
  • What fields of data management are intended? Reporting actual values, predictive analysis, and operation planning?
  • To what level of detail are the values needed?
  • Are current values (up to the last second) essential? Or is a latency (a delay), acceptable? Is it sufficient to process data once per day?
  • Are historical values required? How far back? If values change, is it necessary to identify obsolete values?
  • In calculations, are intermediate results needed as well?

A data modeling directive must address what to do with the data:

  • Are the values read, copied, processed, or presented?
  • Are selection processes used to reduce the set of data?
  • Are tables joined with other tables?
  • Are values transformed? Are they harmonized?
  • Which values must be checked, for instance for referential integrity, against duplicates, for the correct data format, against mathematical errors such as a sum of more than 100%?
  • Is a result presented as a result on the screen, or is it permanently stored?
  • Is data archived or deleted?

A data modeling directive has to address when, and how often, these processes occur. Is it:

  • On demand? (Whenever a business user is interested in the values).
  • At a predefined point in time?
  • Periodically, for instance daily or monthly.
  • Every time the data has changed in the source?

A data modeling directive has to address where data is read and processed:

  • Which source systems are used as a database, and which target systems are used to store values?
  • Which tables or views contain the database?
  • Are calculations applied in the database, or in the application level?
  • Which database is used?
  • Which objects are needed to meet the approved requirements?

Finally, a data modeling directive must address how the data is treated:

  • Are values from imports using flat files, a database connection, or other technologies?
  • What are the join conditions?
  • What are the filter conditions?
  • Which calculations must be carried out?
  • How are plan values derived?
  • Which currencies or units are used, and how can values be converted from one currency to another one?
  • How are values aggregated?

For instance, you must define how key figures from the source are made available. For example, a directive could suggest a raw hub with basic key figures as they're imported from the data source. Business users can then create their own calculations and restrictions on those key figures.

A core hub is another solution that provides predefined, calculated, or restricted key figures for typical use cases. In this case, a data model must define how the new key figures are derived.

You can also provide both options.

Modeling Strategy with Different Reporting Requirements

Different reporting requirements.

It's important to realize that different users in a company may have different requirements related to business reports.

Watch the video to learn about the different reporting requirements for ITelO.

Strategy - Combining Different Requirements

Sometimes, there are good ways to let two requirements coexist:

  • Choose characteristics for drill-down.
  • Add calculations.
  • Create filters for the Top N results.
  • Create highlighting for values below an individually defined target value.
  • In SAP Analytics Cloud, business users can influence the graphical display.
  • Provide a strategic report with a long history and another report with more details for the current year or month.
  • Allow the users to choose one of two different hierarchy versions in one report.
  • List two alternative key figures, such as quantity in KG and quantity in number of pieces.
  • Provide a German HR report without information about the number of sick days per employee, and an American report that orders employees by number of days on leave.
  • In a customer relationship management project, provide a local report showing the number of recurring orders. In a sales project, create another local report showing the number of open orders. However, a global strategy should detect that both use the number of orders, and provide a common ground with harmonized order key figures for both.

Strategy - Target Prioritization

Sometimes, you may decide to exclude certain content or keep it out of the project focus. There might be different reasons, such as:

  • It's impossible to satisfy both targets. For example, it’s impossible to have complex algorithms that are easy to understand at first sight.
  • It's time-consuming and expensive to produce such results.
  • There are legal or compliance barriers.
  • There are global standards. For example, if the global decision was made in favor of showing a standard product categorization based on the first digits of their technical names, other categorizations aren't supported.
  • For users, it's confusing to have different versions.
  • The data sources can't be trusted.
  • Other targets have a higher priority.

If there are conflicts, your priorities must be as follows:

  • Correct values (true, in line with legal requirements, understandable)
  • Required functionality
  • Flexibility (being open for future requirements)
  • Reporting performance
  • Staging performance (correlates with low data volume)

If the conditions change, the targets might be reevaluated, and later projects may be set up to accommodate the targets that were left out.

To avoid confusion, you must aim for:

  • Valid values.
  • Comprehensible data flows.
  • A transparent data origin.
  • A well-structured model.
  • Clear responsibilities.
  • Standard calculations and enterprise-wide available data.
  • Single point of truth.
  • Access control (authorization).

Conflicting requirements from different users.

Therefore, Cathy's requirement about integrating dynamic values from the Internet is out of scope.

Case Study - Start

Analyze business segments.

Different business segments have different processes, issues, and reporting requirements.

Let's first focus on analyzing the business segments of a company, because business segments have different processes, different issues, and different reporting requirements. You may hear the following questions:

What are your business processes?

What are the main reporting requirements of each business?

  • Where are the issues relating to analysis and reporting?

Where are strategic reports relevant, where is the focus on real-time insight, and where is harmonization across systems an issue?

In the example in the figure above, you identify storage and sales as business segments with urgent requests for new reports. To find reporting requirements, start by analyzing the business process of the business segment and the issues.

In storage, the business process involves an automatically controlled inflow and outflow of goods. You may not realize ahead of time that there's a danger of insufficient material stock. You need real time data analysis with good performance on a detailed level.

The sales team wants to integrate data from different source systems and therefore wants to generate reliable harmonized data. In the sales business process, orders are placed in different currencies. The different currencies must be converted to the company's currency. To guarantee reliable data, the results must be saved permanently.

Let's have a more detailed look at the requirements for sales in ITelO.

Requirements for sales in ITelO

Let's have a more detailed look at the requirements for storage in ITelO.

Requirements for storage in ITelO

Separate Business Segments

Storage and sales processes are involved in global reporting. The organization is split into origin, business segment, storage location and organization unit. Separation is organized into different systems and clients.

As a first step, the business segments were analyzed and in this case storage and sales are the two most important business segments to focus on for ITelO.

As a second step, you have to define how the organization is divided. In this case study, the main distinction is the origin of the data. This distinction is important because ITelO and Retailer King 3000 have different data models. Moreover, each organization consists of different organizational units. Each organization unit operates different storage locations (which is especially important for storage, but also for sales).

The third step is to investigate how this separation is represented in the technical systems.

Each business segment stores its data in a set of database tables. Make a note of any tables that are used by more than one business segment. In our case study, the product master data tables are used by both storage and sales.

Identify which field represents the organization unit. If you want to extract values only for one organization unit, apply a filter on this field.

When inspecting the relevant tables, ask yourself the following questions:

  • What fields always have unique values? What fields contain values that can be repeated in different rows?
  • Is there a check table for a field? Can you only enter values that are listed in other tables?
  • What values are likely to change and when?

Bringing Together Separate Segments

Bringing the Storage and Sales segments together.

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  • Published: 29 May 2024

A case–control study on pre-, peri-, and neonatal risk factors associated with autism spectrum disorder among Armenian children

  • Meri Mkhitaryan 1 ,
  • Tamara Avetisyan 2 , 3 ,
  • Anna Mkhoyan 4 ,
  • Larisa Avetisyan 2 , 5 &
  • Konstantin Yenkoyan 1  

Scientific Reports volume  14 , Article number:  12308 ( 2024 ) Cite this article

Metrics details

  • Autism spectrum disorders
  • Public health
  • Risk factors

We aimed to investigate the role of pre-, peri- and neonatal risk factors in the development of autism spectrum disorder (ASD) among Armenian children with the goal of detecting and addressing modifiable risk factors to reduce ASD incidence. For this purpose a retrospective case–control study using a random proportional sample of Armenian children with ASD to assess associations between various factors and ASD was conducted. The study was approved by the local ethical committee, and parental written consent was obtained. A total of 168 children with ASD and 329 controls were included in the analysis. Multivariable logistic regression analysis revealed that male gender, maternal weight gain, use of MgB6, self-reported stress during the pregnancy, pregnancy with complications, as well as use of labor-inducing drugs were associated with a significant increase in the odds of ASD, whereas Duphaston use during pregnancy, the longer interpregnancy interval and birth height were associated with decreased odds of ASD. These findings are pertinent as many identified factors may be preventable or modifiable, underscoring the importance of timely and appropriate public health strategies aimed at disease prevention in pregnant women to reduce ASD incidence.

Introduction

Autism spectrum disorder is a neurodevelopmental disorder by the Diagnostic and Statistical Manual of Mental Disorders, the 5th Edition (DSM-5). It is identified by limited repeating patterns of behavior, activities, and interests, as well as impaired social interaction and communication 1 . A systematic review of research articles spanning from 2012 to 2021 indicates that the worldwide median prevalence of ASD in children stands at 1% 2 . Nevertheless, this reported percentage may not fully capture the actual prevalence of ASD in low- and middle-income nations, potentially leading to underestimations. In 2016, data compiled by the CDC's Autism and Developmental Disabilities Monitoring (ADDM) Network revealed that approximately one out of 54 children in the United States (one out of 34 boys and one out of 144 girls) received a diagnosis of ASD. This marks a ten percent increase from the reported rate of one out of 59 in 2014, a 105 percent increase from one out of 110 in 2006, and a 176 percent increase from one out of 150 in 2000 3 . According to the most recent update from the CDC’s ADDM Network, one out of 36 (2.8%) 8-year-old children has been diagnosed with ASD. These latest statistics exceed the 2018 findings, which indicated a rate of 1 in 44 (2.3%) 4 . To our understanding, there is no existing registry for ASD in the Republic of Armenia (RA). Additionally, there is no available data concerning the incidence and prevalence of ASD in the country.

The etiology of ASD remains unclear despite substantial research on the disorder; yet, important advances have been made in identifying some of the disorder's genetic and neurobiological underpinnings. It has been discovered that ASD is heritable, with environmental variables also being involved 5 , 6 , 7 . According to certain research, ASD is associated with both hereditary and environmental factors 5 , 8 , 9 . It is especially important to identify environmental risk factors because, unlike genetic risk factors, they can be prevented.

There are more than 20 pre-, peri- and neonatal risk factors associated with ASD 10 , 11 , 12 . Prenatal risk factors that have been associated with ASD involve parental age 13 , interpregnancy interval 14 , 15 , immune factors (such as autoimmune diseases, both viral and bacterial infections during pregnancy) 16 , 17 , medication use (especially antidepressants, anti-asthmatics, and anti-epileptics) 18 , 19 , 20 , maternal metabolic conditions (such as diabetes, gestational weight gain, and hypertension) 21 , 22 , 23 , and maternal dietary factors (such as folic acid and other supplement use, maternal iron (Fe) intake, as well as maternal vitamin D levels) 24 , 25 , 26 , 27 , 28 , 29 .

Numerous studies indicate that an increased risk of ASD is linked to several perinatal and neonatal factors. These factors include small gestational age or preterm birth, gestational small or large size, the use of labor and delivery drugs 30 , 31 , 32 , 33 . The risk of ASD associated with cesarean delivery is also a subject of continuous discussion 34 , 35 , 36 . Overall, there is no apparent link between assisted conception and a notably higher risk of ASD, however some particular therapies might make ASD more likely.

This study aimed to determine main pre-, peri- and neonatal risk factors linked to ASD among Armenian children. The following research questions were derived to address the objectives of the study:

What are the primary prenatal risk factors associated with the development of ASD among Armenian children?

How do perinatal factors such as maternal complications during childbirth, labor mode, labor interventions, use of labor-inducing drugs, contribute to the risk of ASD in Armenian children?

What neonatal factors, such as birth weight and gestational age, are linked to the likelihood of ASD diagnosis among Armenian children?

How do socio-demographic factors, such as parental education, gender of the child, number of kids in the family, sequence of the kid, influence the relationship between pre-, peri-, and neonatal risk factors and risk of ASD among Armenian children?

To the best of our knowledge, this was the first study of its kind conducted in Armenia that focused on a variety of factors linked to ASD.

The analysis encompassed a total sample of 497 participants, consisting of 168 children diagnosed with ASD and 329 children without ASD. The descriptive analysis revealed significant differences between the cases and controls on several socio demographic variables as well as prenatal, peri- and neonatal risk factors (see Tables 1 , 2 , 3 and 4 ).

The summary of socio demographic characteristics (Table 1 ). Among the cases (the ASD group), the distribution of gender of the child was significantly different to that in the control group. More specifically, while the distribution of male and female were balanced in the control group (52.89% and 47.11% respectively), the proportion of male children was significantly higher in the ASD group (82.14% and 17.86% respectively, p  < 0.01). Furthermore, the number of children in the families of cases and controls were slightly different. While the proportion of cases and controls who had two children were similar, families with one child were slightly higher in the ASD group compared to the control group (29.94% and 17.02% respectively, p  < 0.01). This picture is reversed with respect to the number of families with more than two children (16.17% and 29.79% respectively). A higher percentage of ASD cases are the first child in the family compared to controls (67.86% vs. 49.54%, p  < 0.01). The proportion of non-married families (those that reported to be single, widowed, divorced etc.) were higher in the ASD group compared to the control group (10.24% and 4.28% respectively, p  < 0.05). The distribution of the level of educational attainment of the parents were also different between the groups. More specifically, the prevalence of university degree among the cases were somewhat lower compared to that in the control group.

The summary of prenatal risk factors (Table 2 ). With respect to prenatal risk factors, there were significant differences between the cases and controls in interpregnancy intervals, self-reported complications and diseases, medication use, vitamin D levels, maternal weight gain, and the self-reported stress during pregnancy. More specifically, the cases had on average lower interpregnancy intervals compared to the controls (M = 12.9 and M = 23.7 months respectively, p  < 0.01). The cases more frequently reported to have had complications during the pregnancy compared to the controls (42.86% and 8.54% respectively, p  < 0.01). The prevalence of reported infectious diseases, other diseases and anemia during the pregnancy were also somewhat higher among the cases compared to the control group. The use of medications was higher among the cases compared to the control group (41.67% and 17.74% respectively, p  < 0.01). Various medications including vitamins, anticoagulants, Paracetamol, MgB6, Duphaston, iron preparation, No-spa, calcium preparation, antibiotics, and Utrogestan showed significant differences in usage between cases and controls (all p  < 0.05) (Table 3 ). The maternal weight gain among the cases was on average higher among the cases compared to the control group (M = 15.4 and M = 13.9 kg respectively, p  < 0.05). The self-reported stress was also more frequent among the cases compared to the controls (56.02 and 10.98% respectively, p  < 0.01). Specifically, comparing data on self-reported stress during different pregnancy periods, it was obvious that 47.06% of mothers of cases and 91.25% of mothers in the control group reported no stress experienced during pregnancy. During the first trimester, 14.38% of mothers with cases of autism reported stress, whereas only 0.94% of mothers in the control group reported stress. In the second trimester, 11.11% of mothers with cases of autism reported stress, compared to 4.06% of mothers in the control group. During the third trimester, 8.50% of mothers with cases of autism reported stress, while 1.88% of mothers in the control group reported stress. Across the entire pregnancy, 18.95% of mothers with cases of autism reported stress, compared to 1.88% of mothers in the control group. The differences in stress levels between the two groups were statistically significant, indicating a potential link between maternal stress during pregnancy and the odds of autism spectrum disorder in offspring.

The summary of perinatal and neonatal risk factors (Table 4 ). The interpretation of the data comparing various peri- and neonatal risk factors between cases (individuals with ASD) and controls (individuals without ASD) are shown below. 83.33% of cases and 91.77% of controls were born within 37–42 weeks of gestation, with a statistically significant difference ( p  < 0.05), whereas 16.67% of cases and 8.23% of controls were born either preterm (before 37 weeks) or post-term (after 42 weeks), also showing a significant difference. There was no statistically significant difference in birth weight between cases and controls (M = 3137.8 and M = 3176.9 g respectively, p  > 0.05). The mean birth height was slightly lower for cases compared to controls (M = 50.4 and M = 50.9 cm), with a statistically significant difference ( p  < 0.05). No statistically significant difference was reported regarding mode of labor. According to the data interventions during labor were reported more in ASD group compared to controls (39.76% and 17.23% respectively, p  < 0.01). Also, labor-inducing drugs were administered more in cases compared to the controls (39.76% and 21.04%, p  < 0.01).

The results of multivariable logistic regression

The multivariable logistic regression analysis indicated significant associations between sociodemographic, prenatal, perinatal and neonatal risk factors. More specifically, male children have 4 times higher odds of having ASD compared to female children (OR = 4.21, CI 2.33–7.63). Among prenatal factors, the maternal weight gain, use of MgB6, the self-reported stress during the pregnancy, as well as pregnancy with complications were associated with a significant increase in the odds of ASD, whereas use of Duphaston was associated with decreased odds of ASD (see Table 5 ). Additionally, the longer interpregnancy interval was associated with decreased odds of ASD diagnosis (OR = 0.708, CI 0.52–0.97). Among peri- and neonatal factors, use of labor-inducing drugs was associated with increase in the odds of ASD diagnosis (OR = 2.295, CI 1.3–4.1), while birth height showed association with decrease in odds (OR = 0.788, CI 0.6–1.0).

Our study provides comprehensive insights into the multifaceted nature of ASD, elucidating the intricate relationships between sociodemographic, prenatal, perinatal, and neonatal factors and ASD risk.

Our findings highlight significant gender disparities in ASD prevalence, with a notably higher proportion (4:1) of male children in the ASD group. This aligns with existing literature demonstrating a male predominance in ASD diagnosis 37 . Meanwhile, Loomes et al. reported 3:1 male-to-female ratio referring to a diagnostic gender bias, where girls meeting the criteria for ASD are at an elevated risk of not receiving a clinical diagnosis 38 . Furthermore, our study highlights the potential impact of family structure on the likelihood of ASD occurrence, indicating higher ASD rates among first-born children and in households where the parents are non-married (divorced, widowed, separated, etc.). A study conducted by Ugur et al. yielded comparable findings, suggesting that the prevalence of being the eldest child was higher in the ASD group compared to the control group 39 . Contrary to this, research conducted in the United States found no evidence to suggest that children diagnosed with ASD are more likely to live in households not composed of both their biological or adoptive parents compared to children without ASD 40 .

The association between prenatal risk factors and ASD risk underscores the importance of maternal health during pregnancy. Our findings suggest that factors such as lower IPIs, maternal complications and diseases during pregnancy, medication use, vitamin D levels, maternal weight gain and maternal self-reported stress during pregnancy may increase the odds of ASD in offspring. It is crucial to note that the higher number of firstborn children among cases compared to the control group could introduce bias when accurately estimating the association between IPI and ASD. Therefore, the coefficients of IPI should be interpreted cautiously. Despite this, we opted not to remove this variable from the model, as IPI is recognized as an important factor in existing literature. Several studies report different results regarding long and short IPIs and ASD risk 14 , 15 , 41 , 42 . The underlying reasons for the link between ASD and short and long IPIs may differ. Short IPIs could be associated with maternal nutrient depletion, stress, infertility, and inflammation, whereas long IPIs may be linked to infertility and related complications. According to our results the frequency of self-reported complications during pregnancy was notably higher among children with ASD compared to the controls. Additionally, there was a somewhat higher prevalence of reported infectious diseases, other illnesses, and anemia during pregnancy among the cases compared to the control group. Several previous investigations have associated maternal hospitalization resulting from infection during pregnancy with an elevated risk of ASD. This includes a substantial study involving over two million individuals, which indicated an increased risk associated with viral and bacterial infections during the prenatal period 12 , 17 . Furthermore, our study results indicate that medication usage during pregnancy was more common among the mothers of cases than the controls. Notably, various medications, including vitamins, anticoagulants, Paracetamol, MgB6, Duphaston, iron preparation, No-spa, calcium preparation, antibiotics, and Utrogestan (micronized progesterone), exhibited significant differences in usage between the cases and controls. According to the results of multiple logistic regression analysis use of MgB6 was associated with a significant increase in the odds of ASD, whereas use of Duphaston (Dydrogesterone), a progestin medication, was associated with decreased odds of ASD. Emphasizing the potential impact of additional variables in evaluating the link between Duphaston and ASD is essential. There is a possibility of factors overlooked in our study. However, after analyzing the included variables, no significant confounding effects were detected. This assessment involved scrutinizing the Cramer’s V value between Duphaston and other variables, and sequentially introducing new variables into the model to evaluate changes in the coefficients of Duphaston. In both cases, no significant confounding effects emerged. In contrast to our results certain researchers have shown that the use of supplements during pregnancy is linked to a decreased risk of ASD in offsprings compared to those whose mothers did not take supplements during pregnancy 43 , 44 . The results of an epidemiology study conducted by Li et al. have showed that prenatal progestin exposure was strongly associated with ASD prevalence, and the experiments in rats showed that prenatal consumption of progestin-contaminated seafood induced autism-like behavior 45 . On the other hand other authors suggest that insufficient maternal progesterone levels might contribute to both obstetrical complications and ASD development 46 . The observed association regarding MgB6 use could potentially be influenced by an unmeasured confounding variable in our study. This warrants further investigation and consideration in future research. Additionally, our study highlighted another modifiable risk factor for ASD that was significantly associated with higher odds of ASD: maternal gestational weight gain. This factor retained its significance even in the multivariable analysis. This finding is consistent with the results of several studies which have shown that maternal metabolic conditions like diabetes, gestational weight gain, and hypertension have been associated with mechanisms pertinent to ASD, such as oxidative stress, fetal hypoxia, and chronic inflammation 23 , 47 . These conditions can induce prolonged or acute hypoxia in the fetus, which might pose a substantial risk factor for neurodevelopmental disturbances.

Furthermore, our findings suggest that the self-reported stress during pregnancy was associated with a significant increase in the odds of ASD. When comparing self-reported stress levels during different pregnancy periods, a notable disparity emerged. The statistically significant differences in stress levels between the two groups were reported in all trimesters of pregnancy suggesting a potential correlation between maternal stress during pregnancy and the odds of autism spectrum disorder in offspring. Several authors report comparable findings suggesting that prenatal maternal stress show significant association with both autistic traits and Attention Deficit Hyperactivity Disorder (ADHD) behaviors 48 , 49 , 50 , 51 . Various mechanisms could be suggested to explain the link between prenatal stress and likelihood of ASD. For instance, stress during pregnancy can trigger physiological changes in the mother's body, such as increased cortisol levels and alterations in immune function, which may impact fetal development and contribute to the risk of ASD. Also, stress may affect placental function, leading to adverse changes in the transfer of nutrients and oxygen to the fetus. Furthermore, prenatal stress can influence gene expression in both the mother and the developing fetus. Certain genes involved in brain development and the stress response system may be affected, potentially increasing the risk of ASD. Additionally, maternal stress may influence parenting behaviors and interactions with the child after birth. High levels of maternal stress may affect the quality of caregiving, which in turn can impact the child's social and emotional development, potentially contributing to ASD risk. Lastly, stress during pregnancy could induce epigenetic modifications, which are alterations in gene expression that occur without changes in DNA sequence. These modifications might affect neurodevelopmental processes, making individuals more susceptible to ASD.

Our study reports notable statistical difference among cases and controls regarding gestational age. According to the results 16.67% of cases were born either preterm (before 37 weeks) or post-term (after 42 weeks), highlighting another significant distinction. Early gestational age is linked with unfavorable health consequences, such as developmental delays and subsequent intellectual impairments throughout childhood and adolescence. Similar results are reported by several authors as well 30 , 31 , 52 . According to our study results birth height was associated with decrease in odds of ASD, however there was no statistically significant difference in birth weight between cases and controls. Some authors demonstrated that infants with birth weights of < 2.5 kg were associated with ADHD and ASD 53 , 54 .

Other than the previously mentioned factors the results of our study have demonstrated that use of labor-inducing drugs was associated with increase in the odds of ASD. The study participants did not report or specify the type of used labor-inducing drugs. Recent investigations have indicated a potential correlation between the utilization of drugs during labor and delivery and the emergence of ASD 55 , 56 , especially given the increased usage of epidurals and labor-inducing medications in the past 30 years. However, conflicting findings exist, with some studies suggesting no link between the administration of labor-inducing drugs and the risk of ASD development 57 , 58 . Recent findings from Qiu et al. propose a potential link between maternal labor epidural analgesia and the risk of ASD in children, particularly when oxytocin was concurrently administered. However, oxytocin exposure in the absence of labor epidural analgesia did not show an association with ASD risk in children 59 . The potential link between the use of labor-inducing drugs and the risk of ASD is complex and not yet fully understood. However, several mechanisms have been proposed to explain this association: for example, labor-inducing drugs, such as oxytocin and prostaglandins, can affect hormonal levels in both the mother and the fetus. These hormonal changes may impact brain development and neural connectivity, potentially increasing the risk of ASD. In addition, labor induction may increase the risk of oxygen deprivation (hypoxia) during labor. Prolonged hypoxia during birth has been linked to adverse neurological outcomes, including an increased risk of neurodevelopmental disorders like ASD. Furthermore, labor induction can lead to an inflammatory response in both the mother and the fetus. This immune system activation may affect neurodevelopmental processes and contribute to the development of ASD. Overall, the relationship between labor-inducing drugs and ASD risk is multifactorial and likely involves interactions between genetic, environmental, and biological factors. Further research is needed to elucidate the specific mechanisms underlying this association.

To our knowledge this is the first study identifying potential pre-, peri- and neonatal risk factors associated with ASD in Armenia.

Limitations and strength

While our study possesses a retrospective design, a notable limitation, it depended on parental recall for details dating back several years. Additionally, the sample was not balanced in terms of gender, with more male children included, potentially introducing selection bias. Despite the relatively small sample size multivariable analysis using the presence or absence of ASD as the dependent variable was implemented to address potential confounding factors.

Nevertheless, our study included a representative sample of the Armenian ASD population, evaluating various factors in comparison with a randomly selected control group matched for age. All ASD diagnoses were made according to DSM-5 by professionals (psychiatrists, pediatricians, neurologists, speech therapists and developmental psychologists), and face-to-face interviews with parents at the time of the interview minimized the risk of information bias.

Our findings indicated that male gender, maternal weight gain, MgB6 usage, self-reported stress during pregnancy, pregnancy complications, and labor-inducing drugs were linked to a significant rise in ASD odds (Fig.  1 ). Conversely, the use of Duphaston during pregnancy, longer interpregnancy intervals, and higher birth height were associated with reduced odds of ASD (Fig.  1 ). These observations underpin the significance of regional investigations to uncover the unique environmental factors contributing to ASD. The implications are profound, as several identified factors may be preventable or adjustable, highlighting the urgency of implementing evidence-based practices and public health interventions. Emphasizing a culture of health promotion, screenings, timely diagnosis, and disease prevention strategies, particularly among pregnant women, holds promise for reducing ASD and related disorders. Moreover, further prospective and focused research is imperative to discern the interplay between various factors and gene-environment interactions that may serve as potential ASD risk factors. Enhanced understanding in this area could lead to earlier detection and improved ASD management. Future studies incorporating analyses of biological samples for genetic, epigenetic, and inflammatory markers will be pivotal in elucidating underlying mechanisms and ushering in a new phase of research focusing on modifiable risk factors for developmental disorders.

figure 1

Sum up scheme showing prenatal, perinatal and neonatal factors which increase, as well as decrease the odds of ASD.

The study population comprised of 497 participants, of which 168 were children with ASD and 329 were typical development controls. The subject recruitment was done during 2021 to 2022. The controls and children with ASD were age matched (3–18 years). The subjects were formally diagnosed with ASD according to DSM-5 by professionals (pediatricians, neurologists, speech therapists and developmental psychologists). The children with ASD were recruited at MY WAY Educational and Rehabilitation Center in Yerevan. Inclusion criteria for cases were age between 3 and 18 years with ASD with diagnosis confirmed using DSM-V. Exclusion criteria for cases were other neurodevelopment disorders other than ASD. The control participants were randomly selected in the same period at Muratsan Hospital Complex. They were not known to have any neurodevelopmental or behavioral disruptions that might be related to ASD. The control group consisted exclusively of individuals diagnosed with simple conditions like flu or a simple routine physical examination.

Questionnaire and data collection

The self-reported questionnaire was completed via a face-to-face interview with the child’s parent. The questionnaire comprised three sections: various aspects of sociodemographic characteristics, prenatal risk factors, and perinatal/neonatal risk factors. Each section addressed specific questions related to these factors for comprehensive data collection. On average, the questionnaire was completed in about 15 to 20 min. The parent had the choice of accepting or refusing to complete the questionnaire. At the end of the process, the completed questionnaires were collected and sent for data entry by using SPSS 21 statistical software. The questionnaire was designed to acquire the information regarding risk factors of ASD. It consisted of different sections: sociodemographic characteristics (e.g., age, sex, family history of ASD, etc.), data on prenatal risk factors (e.g., pregnancy process, complications during pregnancy, infections during pregnancy, other diseases, stress, medication and supplement use during pregnancy, vitamin D level, etc.), questions related to maternal lifestyle risk factors (e.g., smoking, alcohol consumption, gestational weight gain). Respondents were also asked about peri- and neonatal risk factors, including gestational age, gestational size, the use of labor and delivery drugs, mode of delivery, etc.

Ethics disclosure

The study protocol was approved by the Ethics Committee (N 8–2/20; 27.11.2020) of Yerevan State Medical University in line with the principles set forth in the Declaration of Helsinki. Written informed consent was obtained from all the parents of the participants prior to data collection.

Statistical analysis

The data was processed and modelled in Python (version 3.11.6), an open- source software often used for data processing and modelling. The statistical analysis was performed by using the Statsmodels package (version 0.14.1) 60 .

Descriptive statistics were employed to summarize the characteristics of the study variables. Continuous variables were described using means and standard deviations, while categorical variables were presented as proportions. Prior to statistical analysis, numeric variables underwent standardization through the computation of z scores. To evaluate potential multicollinearity among predictor variables, the Variable Inflation Index (VIF) was computed. A predetermined threshold of 5 was established, and variables exceeding this threshold were considered indicative of multicollinearity. Bivariate analyses were conducted to explore associations between predictor variables and the outcome variable (presence or absence of autism diagnosis). T-tests were employed for continuous variables, while chi-squared tests were utilized for nominal and categorical variables. A multivariable logistic regression model was constructed to estimate the relationship between predictor variables and the outcome variable (autism diagnosis). Initially, a comprehensive strategy was employed by first fitting a null model and then iteratively introducing blocks of variables (e.g., socio demographic factors prenatal, peri- and neonatal factors). After introducing the new block of factors, a likelihood ratio test was conducted to evaluate the contribution of the added variables. If the p -value associated with the likelihood ratio test was insignificant ( p  > 0.05), the preference was given to a less complex model. In our analysis all added blocks had significant contribution to the overall fit of the model.

Subsequently, the significance of each variable was systematically assessed by applying a stepwise elimination technique whereby insignificant variables were progressively removed from the model. Similar to the above-mentioned process, at each step, a likelihood ratio test to evaluate the significance of the excluded variable was conducted. If the p -value associated with this test was found to be insignificant ( p  > 0.05), the adoption of a simpler model was favored. This iterative process allowed us to identify the most parsimonious model that retained statistically significant predictors while minimizing unnecessary complexity. Odds ratios (ORs) were computed, accompanied by 95% confidence intervals (CIs), to quantify the strength and direction of these associations.

Data availability

Data can be made available by the corresponding author upon reasonable request.

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Acknowledgements

We express our gratitude to all parents participated in the study.

This work was supported by Higher Education and Science Committee, Ministry of Education, Science, Culture and Sports of RA (24YSMU-CON-I-3AN and 23LCG-3A020), and YSMU.

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M.M. and K.Y. conceived the project; M.M., T.A., A.M., L.A. and K.Y. designed experiments, collected and analyzed data; M.M., T.A., A.M., L.A., and K.Y. wrote the draft; M.M., A.M., and K.Y. edited the manuscript. K.Y. obtained funding and supervised the study. All authors have read and agreed to the published version of the manuscript.

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Mkhitaryan, M., Avetisyan, T., Mkhoyan, A. et al. A case–control study on pre-, peri-, and neonatal risk factors associated with autism spectrum disorder among Armenian children. Sci Rep 14 , 12308 (2024). https://doi.org/10.1038/s41598-024-63240-3

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case study values example

Financial transfer payment and green development transition in backward area: a case study in Jiangxi Province, China

  • Published: 25 May 2024

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case study values example

  • Shengtian Jin 1 ,
  • Zhilong Wu   ORCID: orcid.org/0000-0002-0571-8287 2 ,
  • Bingfei Bao 3 ,
  • Xinmin Zhang 2 &
  • Xing Wang 4  

Green development, as the second generation of sustainable development, is inclusive of ecological civilisation and common prosperity. China has recently initiated large-scale financial transfer payments to promote the green development transition of backward areas. However, the  policy effects are unclear. This study takes Jiangxi Province, the central backward and ecological function area, as an example to explore the dynamic transitions to green development in 80 counties (cities, districts) from 2001 to 2018 and evaluate the policy effects of transfer payment on green development transition based on a multi-period differential model and a panel regression model. Results show that (1) From 2001 to 2018, the green development index composed of economic development index, social security index, and environmental protection index showed an outstanding rising trend in Jiangxi Province, and the economic development index increased the most. (2) The transfer payment from central government to local government can significantly promote the green development transition. The longer the policy implementation time and the larger the transfer payment scale is, the higher the level of green development will be. (3) The per capita general budgetary fiscal revenue, urbanisation rate, proportion of added value of the service industry, and investment rate have positive effects on the green development index. This paper proposes that the Chinese central government may prolong the duration of transfer payment policy and expand the strength and scope of subsidies for key ecological function areas, while the local governments can develop eco-tourism based on ecological advantages and resource endowments. The horizontal ecological compensation mechanism should be improved and highlight the supervision and assessment for transfer payment funds.

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Ecological Compensation and Green Development Institutional Reform in the Yangtze River Economic Belt

case study values example

Can green financial development promote regional ecological efficiency? A case study of China

case study values example

The impact of green taxation on green low-carbon development in Yangtze River Delta region of China—based on mediating effect model and spatial Durbin model

The specific list of the 60 counties (cities, districts) enjoying the transfer payment in key ecological function zones is as follows: Nanchang County, Xinjian District, Jinxian County, Anyi County, Leping City, Fuliang County, Lianhua County, Luxi County, Xiushui County, Wuning County, Yongxiu County, De’an County, Duchang County, Hukou County, Peng County Ze County, Lushan City, Guixi City, Gan County District, Nankang District, Xinfeng County, Dayu County, Shangyou County, Chongyi County, Anyuan County, Longnan City, Dingnan County, Quannan County, Ningdu County, Yudu County, Xingguo County, Ruijin City, Huichang County, Xunwu County, Shicheng County, Zhangshu City, Yifeng County, Jing’an County, Tonggu County, Guangfeng District, Yanshan County, Hengfeng County, Yiyang County, Yugan County, Poyang County, Wannian County, Wuyuan County, Yongfeng County, Taihe County, Suichuan County, Wan’an County, Anfu County, Yongxin County, Jinggangshan City, Nanfeng County, Lichuan County, Yihuang County, Zixi County, Guangchang County, Dongxiang District and Guangxin District. The specific list of counties (cities, districts) not enjoying payment in key ecological function zones is as follows: Shangli County, Fenyi County, Chaisang District, Ruichang City, Yujiang District, Ji’an County, Jishui County, Xiajiang County, Xingan County, Fengxin County, Wanzai County, Shanggao County, Fengcheng City, Gao’an City, Nancheng County, Chongren County, Le’an County, Jinxi County, Yushan County and Dexing City.

Abbreviations

The annual dummy variable

Population density

Per capita general budgetary fiscal revenue

Urbanisation rate

The proportion of added value of the service industry

Investment rate

The transfer payment scale

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Acknowledgements

This research was funded by the National Social Science Foundation of China (22CJY048); the National Natural Science Foundation of China (41861036); the Natural Science Foundation of Jiangxi Province, China (20224BAB203047); and the Science and Technology Project of Education Department of Jiangxi Province, China (GJJ200504).

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Shengtian Jin

College of Applied Economics, Jiangxi University of Finance and Economics, No. 169, East Shuanggang Road, Jingkai District, Nanchang, 330013, China

Zhilong Wu & Xinmin Zhang

Institute of Statistics and Applied Mathematics, Anhui University of Finance and Economics, Bengbu, 233000, China

Bingfei Bao

Government-Invested Project Evaluation Center of Jiangxi Province, Nanchang, 330008, China

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Jin, S., Wu, Z., Bao, B. et al. Financial transfer payment and green development transition in backward area: a case study in Jiangxi Province, China. Environ Dev Sustain (2024). https://doi.org/10.1007/s10668-024-04496-7

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Published : 25 May 2024

DOI : https://doi.org/10.1007/s10668-024-04496-7

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