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Depression and anxiety in systemic lupus erythematosus
Depression and anxiety cause severe loss of quality of life for patients with systemic lupus erythematosus. The causes and factors that contribute to these psychological manifestations in lupus are difficult to disentangle. This study compared clinical, psychological, and demographic factors between lupus patients, depressed patients, and ...
Depression in Patients with Systemic Lupus Erythematosus: A Multicenter
A total of 68 patients with SLE (64 women, 4 men) were enrolled in the study. Forty-six (67.6%) patients were found to have BDI scores indicating depression; of them, only four patients (8.7%) were receiving antidepressant treatments. Higher prevalence of depression was associated with steroid treatment ( P = 0.046).
Depression in systemic lupus erythematosus: Modifiable or inheritable
Study populations. The MR analysis included the largest GWAS meta-analysis on SLE (n = 14,267) as exposure, and a large GWAS of depression (n = 180,866) and another GWAS of major depressive disorder (MDD) (n = 173,005) as outcomes, for whom summary-level data were available (Bentham et al., 2015; Okbay et al., 2016; Wray et al., 2018).All of the participants were of European ancestry and ...
Depression and anxiety in systemic lupus erythematosus: A case-control
Objectives: To evaluate the prevalence of self-perceived depression and anxiety in patients with systemic lupus erythematosus (SLE) and to explore associated factors. Methods: Cross-sectional study of unselected patients with SLE (ACR-97 criteria) and controls with chronic inflammatory rheumatic diseases. Both completed the Hospital Anxiety and Depression Scale (HADS).
A case-control study on health-related quality of life of systemic
Systemic lupus erythematosus (SLE) is a chronic rheumatic autoimmune condition that can cause a wide range of symptoms and problems that may affect the health-related quality of life. The main ...
Association of Depression With Risk of Incident Systemic Lupus
Systemic lupus erythematosus is a serious disease characterized by widespread organ system involvement and is associated with early death. 22 Investigators have posited that depression is a risk factor for SLE on the basis of the high prevalence of depression among existing patients with SLE. 4-6 The largest cross-sectional study found that ...
Depression and anxiety in systemic lupus erythematosus: A case-control
The study population comprised 172 patients and 215 controls. Women accounted for 93% of the patients with SLE. Fibromyalgia was recorded in 12.8% and a history of depression in 17%.
Quality of Life in Systemic Lupus Erythematosus and Other ...
Background: Extensive research has explored SLE's impact on health-related quality of life (H-QoL), especially its connection with mental wellbeing. Recent evidence indicates that depressive syndromes significantly affect H-QoL in SLE. This study aims to quantify SLE's impact on H-QoL, accounting for comorbid depressive episodes through case-control studies. Methods: A case-control study ...
A cross-sectional study on the association of anxiety and depression
Systemic Lupus Erythematosus (SLE) is an autoimmune disease that affects multiple systems and increases the risk of mental disorders such as depression and anxiety. We conducted an observational, single-center, cross-sectional study to investigate the relationship between depression, anxiety, and SLE disease activity. The Patient Health Questionnaire 9 (PHQ-9) was used to assess depression ...
Depression and anxiety in systemic lupus erythematosus
Depression and anxiety cause severe loss of quality of life for patients with systemic lupus erythematosus. The causes and factors that contribute to these psychological manifestations in lupus are difficult to disentangle. This study compared clinical, psychological, and demographic factors between lupus patients, depressed patients, and ...
Prevalence of depression and anxiety in systemic lupus erythematosus: a
Systemic lupus erythematosus (SLE) is a multisystem, autoimmune, connective-tissue disorder with frequent psychological comorbidities, of which depression and anxiety are two common manifestations [1, 2].It has been reported that there were 2 times higher prevalence of depression in SLE patients compared to the general population [].In addition, previous study has reported that the anxiety ...
Association between depression and pain, functional ...
Objective The aim of this study was to explore the effect of depression on pain, disease activity, functional disability and health-related quality of life measured by Visual Analogue Scale, Systemic Lupus Erythematosus Disease Activity Index, Health Assessment Questionnaire and Short Form-36 in patients with systemic lupus erythematosus. Design Meta-analysis. Data sources The PubMed, EMBASE ...
Depression and Cognitive Impairment in Newly Diagnosed Systemic Lupus
Cognitive impairment is present in 80% of patients with systemic lupus erythematosus (SLE) 10 years after diagnosis. The natural history of cognitive dysfunction in newly diagnosed SLE is unknown. ... Neuronal damage caused by SLE disease activity might lead to depression. In a case-control study of 62 unselected patients with SLE and 62 age ...
Depression and systemic lupus erythematosus: a systematic review
The aim of this paper is to review the clinical and psychobiological relationship between depression and SLE. Method: We performed a systematic search of MEDLINE, EMBASE, PsychINFO, using MeSH headings and keywords for 'depression' and 'SLE'. Results: Seventeen studies reported depressive disorders, with prevalence rates in the range 17-75%.
Study Reveals Depression is Often Undiagnosed in People with Systemic
Day-to-day life with lupus can be challenging and take a toll on your mental health. A study examined the prevalence of people with depression and systemic lupus erythematosus (SLE) and found depression was highly prevalent, but often undiagnosed. The study included 40 people (37 female; 3 male) with SLE who had no history of depression or anxiety.
Anxiety and depression prevalence and their risk factors in lupus
Several clinical studies have investigated the prevalence of anxiety and depression in SLE patients. One study discloses that the prevalence of anxiety and depression is 44.0% and 36.0%, respectively in SLE patients. 10 Besides, another study reveals that the frequency of anxiety and depression is 34.0% and 51.0%, respectively in SLE patients ...
Systemic Lupus Erythematosus (SLE) and Depression
As is true for many others, people with systemic lupus erythematosus (SLE) can get depressed and find that their ability to enjoy life and to function effectively is reduced by feelings, thoughts, and behaviors related to depression. Depression can stem from a life stress, like a medical illness (for instance, lupus) or the loss of a loved one.
Clinical trial outcomes for SLE: what we have and what we need
The paradigm of drug approval in SLE currently relies on successful large phase III randomised controlled trials and a set of primary, secondary and additional end points. Taken together, these outcomes offer a nuanced understanding of the efficacy and safety of the investigational agent. In this review, we thoroughly examine the main outcomes used in SLE trials and highlight unmet ...
Prognosis and improved outcomes in major depression: a review
The European "Group for the Study of Resistant Depression" (GSRD) multi-site study found that age at first treatment (i.e., early-onset and early treatment), age, timespan between first and ...
Frontiers
The purpose with of this study was to investigate the link between emotion dysregulation and insomnia disorder as well as the impact possible role of psychiatric comorbidity on the association. More specifically, the aim was to examine whether the elevations in emotion dysregulation in insomnia are dependent on co-occurring psychiatric comorbidity, in this study defined as anxiety disorders ...
Post-COVID-19 depression and anxiety in patients with systemic lupus
Patients and Methods. This is a case-control study including 120 adult Egyptian patients with SLE: sixty patients with SLE who were proven previously to be positive for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) by polymerase chain reaction (PCR) and recovered during the 3 months prior to the study were included in the case group and an equal number of age- and sex-matched ...
Frontiers
The COVID-19 pandemic emphasized the importance of public spaces. Accessing public spaces during the pandemic improves physical health, reduces feelings of loneliness, and lessens depression. However, not all public spaces can provide an effective response during the pandemic. The public spaces' ability to respond to the pandemic varies depending on their resilience level, which refers to the ...
Up to 40pc of mental health conditions are linked to child abuse and
The research has found that childhood maltreatment is responsible for up to 41 per cent of common mental health conditions including anxiety, depression, substance abuse, self-harm and suicide ...
JMSE
It is beneficial in terms of the theoretical significance and application prospects to define the structure and reservoir development model of the lower Paleozoic unconformity in the Jiyang Depression of Bohai Bay Basin, China, for oil and gas exploration of unconformity in carbonate strata. Geological and geochemical evidence shows that a regional unconformity formed during the Huaiyuan ...
Case Report: When a patient with depression is feeling sleepy, be aware
When a patient with depression is feeling sleepy, be aware of sleep apnoea. A 67-year-old man was referred to an outpatient clinic of geriatric psychiatry because of persistent symptoms of depression and anxiety, accompanied by sleepiness. The latter had been evaluated multiple times in the general practice over several years; each time it was ...
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Depression and anxiety cause severe loss of quality of life for patients with systemic lupus erythematosus. The causes and factors that contribute to these psychological manifestations in lupus are difficult to disentangle. This study compared clinical, psychological, and demographic factors between lupus patients, depressed patients, and ...
A total of 68 patients with SLE (64 women, 4 men) were enrolled in the study. Forty-six (67.6%) patients were found to have BDI scores indicating depression; of them, only four patients (8.7%) were receiving antidepressant treatments. Higher prevalence of depression was associated with steroid treatment ( P = 0.046).
Study populations. The MR analysis included the largest GWAS meta-analysis on SLE (n = 14,267) as exposure, and a large GWAS of depression (n = 180,866) and another GWAS of major depressive disorder (MDD) (n = 173,005) as outcomes, for whom summary-level data were available (Bentham et al., 2015; Okbay et al., 2016; Wray et al., 2018).All of the participants were of European ancestry and ...
Objectives: To evaluate the prevalence of self-perceived depression and anxiety in patients with systemic lupus erythematosus (SLE) and to explore associated factors. Methods: Cross-sectional study of unselected patients with SLE (ACR-97 criteria) and controls with chronic inflammatory rheumatic diseases. Both completed the Hospital Anxiety and Depression Scale (HADS).
Systemic lupus erythematosus (SLE) is a chronic rheumatic autoimmune condition that can cause a wide range of symptoms and problems that may affect the health-related quality of life. The main ...
Systemic lupus erythematosus is a serious disease characterized by widespread organ system involvement and is associated with early death. 22 Investigators have posited that depression is a risk factor for SLE on the basis of the high prevalence of depression among existing patients with SLE. 4-6 The largest cross-sectional study found that ...
The study population comprised 172 patients and 215 controls. Women accounted for 93% of the patients with SLE. Fibromyalgia was recorded in 12.8% and a history of depression in 17%.
Background: Extensive research has explored SLE's impact on health-related quality of life (H-QoL), especially its connection with mental wellbeing. Recent evidence indicates that depressive syndromes significantly affect H-QoL in SLE. This study aims to quantify SLE's impact on H-QoL, accounting for comorbid depressive episodes through case-control studies. Methods: A case-control study ...
Systemic Lupus Erythematosus (SLE) is an autoimmune disease that affects multiple systems and increases the risk of mental disorders such as depression and anxiety. We conducted an observational, single-center, cross-sectional study to investigate the relationship between depression, anxiety, and SLE disease activity. The Patient Health Questionnaire 9 (PHQ-9) was used to assess depression ...
Depression and anxiety cause severe loss of quality of life for patients with systemic lupus erythematosus. The causes and factors that contribute to these psychological manifestations in lupus are difficult to disentangle. This study compared clinical, psychological, and demographic factors between lupus patients, depressed patients, and ...
Systemic lupus erythematosus (SLE) is a multisystem, autoimmune, connective-tissue disorder with frequent psychological comorbidities, of which depression and anxiety are two common manifestations [1, 2].It has been reported that there were 2 times higher prevalence of depression in SLE patients compared to the general population [].In addition, previous study has reported that the anxiety ...
Objective The aim of this study was to explore the effect of depression on pain, disease activity, functional disability and health-related quality of life measured by Visual Analogue Scale, Systemic Lupus Erythematosus Disease Activity Index, Health Assessment Questionnaire and Short Form-36 in patients with systemic lupus erythematosus. Design Meta-analysis. Data sources The PubMed, EMBASE ...
Cognitive impairment is present in 80% of patients with systemic lupus erythematosus (SLE) 10 years after diagnosis. The natural history of cognitive dysfunction in newly diagnosed SLE is unknown. ... Neuronal damage caused by SLE disease activity might lead to depression. In a case-control study of 62 unselected patients with SLE and 62 age ...
The aim of this paper is to review the clinical and psychobiological relationship between depression and SLE. Method: We performed a systematic search of MEDLINE, EMBASE, PsychINFO, using MeSH headings and keywords for 'depression' and 'SLE'. Results: Seventeen studies reported depressive disorders, with prevalence rates in the range 17-75%.
Day-to-day life with lupus can be challenging and take a toll on your mental health. A study examined the prevalence of people with depression and systemic lupus erythematosus (SLE) and found depression was highly prevalent, but often undiagnosed. The study included 40 people (37 female; 3 male) with SLE who had no history of depression or anxiety.
Several clinical studies have investigated the prevalence of anxiety and depression in SLE patients. One study discloses that the prevalence of anxiety and depression is 44.0% and 36.0%, respectively in SLE patients. 10 Besides, another study reveals that the frequency of anxiety and depression is 34.0% and 51.0%, respectively in SLE patients ...
As is true for many others, people with systemic lupus erythematosus (SLE) can get depressed and find that their ability to enjoy life and to function effectively is reduced by feelings, thoughts, and behaviors related to depression. Depression can stem from a life stress, like a medical illness (for instance, lupus) or the loss of a loved one.
The paradigm of drug approval in SLE currently relies on successful large phase III randomised controlled trials and a set of primary, secondary and additional end points. Taken together, these outcomes offer a nuanced understanding of the efficacy and safety of the investigational agent. In this review, we thoroughly examine the main outcomes used in SLE trials and highlight unmet ...
The European "Group for the Study of Resistant Depression" (GSRD) multi-site study found that age at first treatment (i.e., early-onset and early treatment), age, timespan between first and ...
The purpose with of this study was to investigate the link between emotion dysregulation and insomnia disorder as well as the impact possible role of psychiatric comorbidity on the association. More specifically, the aim was to examine whether the elevations in emotion dysregulation in insomnia are dependent on co-occurring psychiatric comorbidity, in this study defined as anxiety disorders ...
Patients and Methods. This is a case-control study including 120 adult Egyptian patients with SLE: sixty patients with SLE who were proven previously to be positive for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) by polymerase chain reaction (PCR) and recovered during the 3 months prior to the study were included in the case group and an equal number of age- and sex-matched ...
The COVID-19 pandemic emphasized the importance of public spaces. Accessing public spaces during the pandemic improves physical health, reduces feelings of loneliness, and lessens depression. However, not all public spaces can provide an effective response during the pandemic. The public spaces' ability to respond to the pandemic varies depending on their resilience level, which refers to the ...
The research has found that childhood maltreatment is responsible for up to 41 per cent of common mental health conditions including anxiety, depression, substance abuse, self-harm and suicide ...
It is beneficial in terms of the theoretical significance and application prospects to define the structure and reservoir development model of the lower Paleozoic unconformity in the Jiyang Depression of Bohai Bay Basin, China, for oil and gas exploration of unconformity in carbonate strata. Geological and geochemical evidence shows that a regional unconformity formed during the Huaiyuan ...
When a patient with depression is feeling sleepy, be aware of sleep apnoea. A 67-year-old man was referred to an outpatient clinic of geriatric psychiatry because of persistent symptoms of depression and anxiety, accompanied by sleepiness. The latter had been evaluated multiple times in the general practice over several years; each time it was ...