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  • Neuroscience Personal Statement Examples

Below are very good neuroscience personal statement examples, as well as FAQ. Read and use these personal statements as inspiration to write your university application. 

Neuroscience Personal Statement Example

As a lifelong science enthusiast, I have always been fascinated by the complexity of the natural world and the mysteries that await discovery. From my early love of dinosaurs to my current interest in the intricate workings of the human brain, I have pursued my passion for science through my academic studies and personal pursuits. Now, as I embark on the next phase of my educational journey, I am thrilled at the prospect of studying neuroscience at university.

My BTEC in Science has provided me with a solid foundation in various scientific fields, including psychology , physiology, and biochemistry. However, it is the study of the brain that truly captivates me. I am eager to delve into the intricate connections between different disciplines that enable us to understand this complex organ and potentially cure illnesses that afflict humanity. My interest in neuroscience was further sparked by reading Louann Brizendine’s “The Female Brain” and following Dr Helen Fisher’s work on the biological basis of human behaviour.

My love of problem-solving and new inventions is evident in my interests outside of academia, including my passion for science fiction films like “Transformers,” “Inception,” and “Iron Man.” The engineering involved in creating sleek and fast cars like my favourite, the Maserati Quattroporte GTS, fascinates me and underscores my appreciation for scientific knowledge and its applications.

In addition to my academic pursuits, I am an avid sports enthusiast and have gained valuable experience in teamwork and leadership through my involvement in sports programmes. I obtained my Sports Leadership Award and shared my skills in basketball and other sports with children. I regularly participate in my local Kickz football scheme and have been featured in video clips for my local basketball team. I believe that teamwork and collaboration are essential to achieving humanity’s goals, just as the relationships between different scientific disciplines are vital to advancing our understanding of the world.

Having lived in Russia for nine years, I have developed a deep appreciation for different cultures and a desire to contribute positively to the world. My multilingualism in English, Urdu, Russian, Spanish, and French reflects my ability to communicate effectively with people from diverse backgrounds. My work experience at Office Angels Recruitment Agency taught me the importance of organization, focus, and teamwork in achieving goals.

As part of the Imagine Croydon scheme, I presented my ideas for improving my borough to the Mayor of Croydon Council, which reflects my passion for making a positive impact on the world. I am inspired by the allegory coined by Oliver Sacks about cognitive processes being akin to learning a new piece of music, and I am convinced that our plastic neural networks can be rewired to improve our cognitive abilities.

One of my primary aims in studying neuroscience is to gain a deeper understanding of the evolution of the brain and its development from childhood to adulthood. I believe that this knowledge holds the key to unlocking the mysteries of the prefrontal cortex and further advancing our understanding of the brain’s capabilities.

Despite facing medical challenges that impacted my ability to concentrate fully during my A-level studies, I found the subjects engaging and interesting. I have also been helping GCSE students in their science, Spanish, and English studies, which has reinforced my love of teaching and sharing knowledge with others.

I am excited to pursue my passion for neuroscience at university and apply my problem-solving skills, teamwork experience, and multilingualism to contribute positively to the field. I am confident that my love of science, combined with my curiosity and thirst for knowledge, will make me a valuable addition to any neuroscience programme.

Cognitive Neuroscience Personal Statement

From my early fascination with dopamine and neurotransmitters to my current interest in Alzheimer’s disease and its treatment, my passion for neuroscience has driven my academic and personal pursuits. I was inspired by a Psychology course in my fourth year and went on to study Chemistry and Biology, where I was captivated by the endocrine and neurological systems. My love of reading has led me to stay up to date on medical world affairs, with Ivor Browne’s autobiography and British journal articles on psychiatry illnesses and drug use among my favourite sources.

My interest in Alzheimer’s disease has motivated me to volunteer at Alzheimer’s homes, where I have performed for and entertained elderly patients. My enterprise class in transition year taught me essential entrepreneurial skills, including initiative, problem-solving, and pragmatism, and I led my group to be the only one to make a profit. Drama is one of my main hobbies, and I have performed on stage several times, particularly enjoying improvisation.

My EPQ explored the most effective treatment for Alzheimer’s disease, leading me to conclude that a combined treatment plan including pharmaceuticals and activities for healthy brain stimulation, such as music, might be most effective. I am also interested in using treatments that have not previously been considered for mainstream medical applications, such as curcumin, and postulated that hormone reduction played a vital role in the progress of Alzheimer’s disease.

My work experience with Dr Gregory Wildgoose and his research team at UEA allowed me to gain a better understanding of the industry I am hoping to enter, despite the electrochemistry I was working on not being directly connected to my field of interest. My greatest personal achievement has been travelling in Malaysia with World Challenge, where I raised funds to help redecorate an orphanage for disabled children and rebuild a hatchery on the site of a turtle conservation area, teaching me essential skills such as time management, budgeting, leadership, teamwork, and self-motivation.

I am excited to pursue a degree in Neuroscience and contribute to the field in the future. I am particularly interested in the narrow field of research and development and hope to be an eternal student, continually stimulated by everything I encounter. Studying at a university far from home is ideal for me, as I relish the idea of starting afresh and facing new challenges and responsibilities. I am quick on my feet, cope well under pressure, and pay attention to detail, all skills that will serve me well in the field of neuroscience.

In conclusion, my passion for neuroscience has driven my academic and personal pursuits, from my early fascination with neurotransmitters to my current interest in Alzheimer’s disease and its treatment. My enterprise skills, love of reading, and volunteering experience have prepared me well for the challenges of university study, while my achievements have taught me essential skills such as leadership, teamwork, and self-motivation. I am excited to contribute to the field of neuroscience in the future and am eager to learn every detail to continually be stimulated.

FAQ Neuroscience Personal Statements

A strong Neuroscience Personal Statement is important because it is typically the first opportunity for a university admissions tutor to get to know you beyond your academic record and test scores. It allows you to showcase your passion for neuroscience and demonstrate your suitability for the programme. 

A personal statement for the neuroscience course should highlight your academic achievements, experience, skills, and aspirations. It should demonstrate your passion for neuroscience and your understanding of the subject matter. You should explain why you are interested in neuroscience, what you hope to gain from the programme, and how it fits into your future goals. 

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Neuroscience: Personal Statement

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Published: Jun 13, 2024

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personal statement related to neuroscience

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  • Neuroscience personal statement

Neuroscience Personal Statement Example

Sample statement.

Studying Neuroscience means you’ll be on the frontline of new scientific discoveries and could lead to a highly rewarding career. However, you might find that writing your personal statement is the biggest hurdle.

To give you a push in the right direction here is an example personal statement of someone applying to study Neuroscience:

From an early age I was interested in science and thoroughly enjoyed creating “experiments” with home science kits and other household items. As I grew older I understood just how many ground breaking discoveries are made in the world of science every day and I know that a career where I can be a part of that is right for me.

At school I excelled in science subjects and relished the chance to study Biology and Chemistry at A Level. By studying these subjects alongside Psychology and Sociology gave me a chance to develop more in-depth knowledge of how the human mind works and how we form relationships with each other and the world around us.

During my time at college I worked part time as a carer in a nursing home specialising in elderly dementia and Alzheimer’s patients. This gave me first-hand experience of how fragile and complex the human brain is.

Outside of school I fit volunteering at my local charity shop around my studies and part time employment. This gives me the chance to build on my personal, teamwork, and communication skills that I have gained as a result of working in the care home.

I look forward to my time at university taking me to a new area where I can volunteer for another charity and continue to develop my skills and make new connections with local people.

My time at the care home has inspired me to want to help people who suffer with degenerative brain disorders and to strive to discover better forms of treatment, or even a prevention or cure.

I hope that a career in Neuroscience will allow me to improve the lives of others, if only in a small way.

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Free PDF: The 4 questions every SOP must answer → Master’s or PhD

personal statement related to neuroscience

How to Write Your Neuroscience SOP: A PhD Success Story

  • By Jordan Dotson
  • Updated: August 13, 2024

How to Write Your Neuroscience Statement of Purpose Brain Image

I fully admit, editing a neuroscience statement of purpose is a daunting task. When working with a PhD applicant, it’s even more intimidating. The research nuances are mindboggling. (Literally?) Molecular assays and signaling pathways – the  jargon is dense, and the details are important. It takes a great deal of work to make sure the SOP portrays the applicant in the clearest and most compelling way.

Luckily however, some students are so awesome they make this job a breeze.

As a former professional ballerina with a 4.0 GPA, two years of neuroscience research, and publications in TWO different majors, Martina is the type of student who makes the rest of us feel lazy. Yet, like most STEM students, Martina didn’t feel 100% confident about portraying her candidacy in writing.

I’m telling you, this task is hard for everyone.

This was especially true during the super-competitive 2020-21 admissions cycle, when lots of amazing PhD applicants received surprisingly unfortunate results.

Yet, coming from a small regional college, and with only two weeks of revision, Martina wrote, edited, and perfected one of the most amazing SOPs I’ve ever read. And her success speaks for itself.

The Results

Martina applied to 12 top-ranked R1 programs . She received interview offers from 10. She interviewed at 7, was accepted at 5, and ultimately enrolled at her top-choice school.

“I feel really lucky to have done so well during this crazy application season,” she said.

But in my opinion, luck had little to do with it. Instead, Martina’s success was born in her incredible work ethic, her research accomplishments, and her willingness to write the strongest neuroscience statement of purpose possible.

What’s great about this SOP?

I don’t think I’ve ever seen a more perfect utilization of the Structure is Magic SOP template , and this is something that should inspire every applicant in every type of degree program or academic field.

  • Two paragraphs in the Introductory Frame Narrative
  • Two paragraphs for Why This Program
  • Two paragraphs for Why I’m (Overly) Qualified
  • One resounding frame narrative conclusion paragraph

The frame narrative starts with a highly memorable story. (She was a professional ballerina!) But like all great SOPs, it quickly moves into an intellectual journey. This journey concludes with a beautifully specific “academic goal.” It relates her research proposal to a larger humanistic issue, but lists the specific problems she hopes to explore in her PhD:

“ I hope to continue elucidating hypothalamic metabolic circuits, and exploring how obesogenic diets affect long-term developmental outcomes in relation to the normal functioning of the satiety hormone leptin. ”

PRO TIP: If you don’t know how to write a hyper-specific academic goal, my free SOP Starter Kit will tell you exactly how.

Really, I love how Martina took great pains to elaborate her research proposal (just as I described in this previous article ). It’s a symphony of intellectual depth and research competence. As she describes her potential PIs’ work, she constantly links it to her own experience (and her future goals).

She doesn’t just say: “Dr. So-and-So’s work is fascinating, and I hope to contribute.”

Instead, she says:

“[Dr. So-and-So’s work] has been critical to my understanding of sensitive periods for the trophic actions of leptin in the brain…[and] my experience with quantitative immunohistochemistry and RT-qPCR make me well qualified to contribute to such research…[and this is why] I am interested in studying the role LepRb and its developmental actions might play in leptin resistance and obesity in adulthood.”

Notice that 3-point argument? That’s the SOP in a nutshell.

  • The professor’s work on X intrigues me…
  • Because it correlates to my past experience in Y…
  • And this is why I’m confident about studying the related topic Z at this university.

With every word, Martina crafts a persuasive intellectual argument. It’s not about her . It’s about the research . It shows that she has a solid understanding of how she might fit into these professors’ labs, and what they might accomplish together .

When Martina finally presents her credentials, it’s almost an afterthought. She’s written with such nuance and depth that the reader already knows she’s an incredible neuroscience researcher. Her successes as an undergraduate are icing on the cake.

Seriously, this essay makes me giddy. But enough of my rambling. Let’s take a look at the SOP that helped Martina achieve such awesome results:

A Brilliant Neuroscience Statement of Purpose

When I ended my career with the California Ballet in 2016, I looked forward to an academic experience studying the metabolic and neurological systems which had silently governed my physical reality as a performer for so long. Surprisingly, the opportunity proved more rewarding than I could have imagined. The perseverance I cultivated as a ballerina proved essential as I immediately dove into the Psychology, Biology, and Philosophy curricula at Stark University, and I soon developed an interest in the neural regulation of metabolic development. After joining Dr. Jean Grey’s research lab in my sophomore year (a position I have maintained ever since), I had the great fortune of studying the effects of obesogenic diets on conserved signaling pathways governing metabolic regulation in Drosophila melanogaster. Through this work, I have become singularly fascinated with the myriad factors that contribute to the growing obesity epidemic, and its developmental origins in particular.

The questions that underpin our work in the Grey Lab are compelling. How do critical or sensitive periods of neuroendocrine development contribute to long-term functioning in animals and humans at the behavioral and cellular levels? Interestingly, current research at Gotham University seeks answers to these very questions, and that is precisely why I apply as a PhD candidate to the interdisciplinary Graduate Program in Neuroscience.

At GU, I hope to continue elucidating hypothalamic metabolic circuits, and exploring how obesogenic diets affect long-term developmental outcomes in relation to the normal functioning of the satiety hormone leptin. I am quite interested in the work of Dr. Jonathan Crane, whose research on the development of hypothalamic circuits, and how they regulate feeding behavior, has been critical to my understanding of sensitive periods for the trophic actions of leptin in the brain. I believe my experience with quantitative immunohistochemistry and RT-qPCR make me well qualified to contribute to such research. In fact, Dr. Crane’s continuing work on the molecular signals connecting postnatal overnutrition to abnormal development of hypothalamic circuits represents questions similar to those that drew me to studying the neurobiological aspects of feeding and development. It also defines the kind of work I hope to accomplish as a doctoral candidate. While Dr. Crane’s investigation into the necessity of LepRb for typical hypothalamic development is fascinating, I am interested in studying the role LepRb and its developmental actions might play in leptin resistance and obesity in adulthood.

Additionally, Dr. Otto Octavius’s research on the effects of high developmental sugar consumption on memory circuits is fascinating to me; it dovetails nicely with my experience using high-fructose corn syrup diets to mimic obesogenic conditions, while using both behavioral and molecular assays such as weight, food intake, and RNA sequencing to investigate physiological and neural changes. For these reasons, I believe I would be a great fit in either the Crane Lab or the Octavius Lab, given my experience researching metabolic development at both the behavioral and cellular level.

Having averaged 25 research hours per week during the last few academic years, and up to 50 during the summers, I believe I have acquired all the necessary tools to succeed as a graduate student at GU. I lead the developmental subdivision at the Grey Lab, a project investigating how the timing of a high-fructose diet during development affects cellular and behavioral outcomes in adult Drosophila as it relates to unpaired 1 – the Drosophila analog of leptin – and its downstream JAK/STAT signaling pathway. In investigating this evolutionarily conserved circuit, I created a new experimental protocol for carrying out developmental feeding experiments with Drosophila larvae, as well as performing behavioral assays related to feeding such as weight, two-choice feeding preference, and capillary feeding assays. Additionally, I have performed dissections and imaging with destabilized transgenic fly lines to quantify neuropeptide-f and STAT92E expression at both the cellular and terminal levels, hoping to elucidate the potential role of SOCS36E in receptor functioning. This work has lead to me identifying a unique obese phenotype related to early dysregulation of unpaired 1, of which I was slated to perform RNA sequencing prior to COVID-19 related disruptions.

Pursuing these research projects as an undergraduate has been a monumental task, I admit, so I am proud to have maintained a 4.0 GPA, all while achieving numerous successes in my second major, Philosophy. Having coauthored a paper in the American Journal of Bioethics, as well as winning the California Philosophical Association’s undergraduate award and presenting at their annual conference, I am all the more confident in my readiness to succeed at GU.

When my career in ballet drew to a close, I looked forward to fully devoting my time to the study of the human brain’s infinitely curious adaptive processes. Now, I find myself in a similar situation, once again eager to devote myself to the study of the developing brain and how it governs metabolic regulation. The rigorous standards of The Grey Lab, along with Dr. Grey’s strict belief in personal responsibility, have shown me that (like dance) true intellectual contributions are only possible through perseverance, determination, and a ruthless eye for weakness in both experimental design and execution. Balancing laboratory workloads with a full schedule of undergraduate classes has been a taxing endeavor, but this too has been essential to my growth as a researcher. Today, I look forward to the new intellectual challenges that Gotham University will provide, and I am sure that I will discover new passions, curiosities, and questions as I prepare for my hopeful career in academia, as a professor.

The SOP Symbolizes and Summarizes Your Entire Candidacy

Again, I admit that Martina is a rock star. Not all of us can mimic her remarkable undergraduate experience. But we CAN learn from the thoughtfulness of her writing.

Martina didn’t cobble together an essay and expect her credentials to win the day. Instead, she understood that this piece of writing, these 900 words, represent everything about who she is and what she aims to be. Her neuroscience statement of purpose wasn’t just a part of her application, one more sheet of paper in the pile. It represents her entire application. It integrates all of her strengths and intelligence. It presents her research goals fully, and convinced no small number of readers that she is a clear communicator too.

Everything we NEED to know about Martina is in this SOP. There’s no fluff. No out-of-place material better left to the CV. It’s just 100% airtight writing about a talented scholar and her specific goals.

I’m incredibly grateful to Martina for allowing me to publish this (pseudonymized) SOP. Students like her inspire me every day, and I hope her example inspires you as well.

Get Admitted Using a Proven Formula

Learn my detailed, step-by-step process for writing a brilliant statement of purpose that floods your inbox with admission offers and launches the next phase of your career. WriteIvy’s courses have helped hundreds of Master’s and PhD students get accepted into their dream schools. Will you be next?

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Personal Statement:Neuroscience With Psychology

Neuroscience with psychology personal statement.

What is the most extraordinary and complex creation in the universe? My answer would have to be the human brain. Capable of controlling what we do, what we eat, how we move, and storing our precious memories. I’ve always known from a young age that whatever I wanted to do in the future would include working with children, which is why I plan to train to become a neuropsychologist and specialise in paediatrics. How children have the ability to develop and grow has always fascinated me. I undertook work experience at St Margaret’s Primary School for two weeks and had the best experience possible. It interested me how children reacted in different situations, making my mind question the hows and whys of their development. I thoroughly enjoy my A level subjects; Biology, Psychology and English Literature. Biology and Psychology are two subjects I feel have influenced me. They have helped me to gain and develop my research ability and to carry out thorough investigations and experiments. Practicals have helped me learn how to study both independently and in a group and I have learnt how to complete detailed write-ups. Using different research methods, gathering data, analysing findings, drawing up conclusions and evaluations are some of the aspects of carrying out investigations I have learnt. I feel that this will help me in my chosen field because I also have to carry out research and investigations. Biology; the physiological study of living organisms and Psychology; the study of the human mind, thought and behaviour have continued to intrigue me throughout my time at sixth form. I particularly enjoyed the cognitive approach in psychology, how it gives an insight into human’s perception and their thought processes. I found the case of HM very interesting; not only did it revolutionise the study of cognitive neuropsychology, but it helped us to make links between memory, brain function and structure. All of my subjects have helped me to improve my essay writing, whether it was writing scientific reports in Biology or comparative essays in English Literature and Psychology. I feel this is helpful for my chosen course as I know that I have to write up my findings from studies I may have carried out and with my dissertation in my final year. I am actively involved in school life and the community, have officially done 40 hours of community service in my school and am an avid musician. I have been playing the trombone since 2001, am currently working towards Grade 8 trombone practical and have passed my Grade 5 music theory. I’ve taken part in every school musical production since my time at the school, am a member of both the school and borough orchestra and was part of the borough’s advanced choir. This relates to my course as I believe there’s a link between music and cognitive development. It has been proven in Piaget’s theory of cognitive development and in various studies for music psychology that music has a positive effect on the brain by increasing progress and efficiency. Reading is another hobby of mine. I feel that reading increases knowledge and cognitive development. I’ve always wondered how the human mind is creative enough to produce the most remarkable and riveting stories. I enjoy classical books such as Jane Austen’s ‘Pride and Prejudice’. I particularly enjoyed a biography I read by Doctor Benjamin Carson, a gifted neurosurgeon and director of paediatric neurosurgery at Johns Hopkins hospital in America; he was also the lead surgeon in one of the world’s first successful hemispherectomies in 1987. I currently have a part-time job at NEXT, which I enjoy very much. I feel that it has helped me to gain responsibility and manage money, which will benefit me for university. I look forward to the challenges I will face at university and am looking forward to exploring my course. I am conscientious and love to learn new things, enabling me to enthusiastically contribute to university life and what it has to offer.

Universities Applied to:

  • University of Nottingham - Conditional Offer ABB
  • University of Leicester - Conditional Offer ABB
  • University of Westminster - Conditional Offer CCC
  • University of Keele - Conditional Offer BBB  Insurance
  • University of Manchester - Conditional Offer ABB  Firm

Grades Achieved:

  • English Literature (A2) - A*
  • Biology (A2) - B
  • Psychology (A2) - B

General Comments:

My course at Manchester was Cognitive Neuroscience and Psychology

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personal statement related to neuroscience

CollegeLAH

CollegeLAH is a website by the students for the students, featuring the honest story of applications and university life as told by Malaysians. It’s a non-profit social project to help Malaysian students to achieve their higher-education dreams and inspire them to reach their full potential. 

Neuroscience Personal Statement

This personal statement got her into neuroscience courses at  university college london, king’s college london, university of edinburgh, university of manchester and university of bristol ..

When I first attempted meditation, I was engrossed by the state of emptiness in my mind I was able to achieve, which led me to contemplate how the brain actually functions. Subsequently, I was exposed to the Buddhist view of perception and consciousness; as a keen scientific inquirer, this sparked my fascination towards investigating matters of the mind from a scientific perspective. From reading David’s Eagleman’s ‘Incognito’, the power of the subconscious mind in executing our auto responses left me enthralled and pondering upon the complexity of the neural processes that underpin our behaviour.

I chose to study Biology and Chemistry in IBDP in order to gain deeper understanding of the anatomy and the chemistry of the human body. The neurobiology option in Biology particularly interested me as it explores not only the structure of the brain but also how behaviour and cognitive abilities, to a certain extent, have been genetically predetermined by the process of natural selection. This led me to further inquire into the relationship between our brain and behaviour in my Theory of Knowledge presentation, in which I investigated the accuracy of our sense perception as a way of judging human behaviour from a neuroscientific viewpoint. In addition, I learnt in mathematics how the subject can be applied to problem solving in various instances; for example, the way in which graph theory can be used to map and model the vast network of neurons in the brain.

During the summer, I completed an internship at the School of Biosciences at Taylor’s University. I had the chance to work with postgraduate students of wide-ranging cultural backgrounds which provided me with an eye-opening experience of being immersed within the scientific community for the first time. Throughout my time there, I was required to independently carry out my own experiments using advanced lab techniques, which helped me to develop my investigative and analytical skills. I was also presented with the opportunity to attend an international food science conference, witnessing the exchange of scientific knowledge and opinions at a highly intellectual level.

Furthermore, I shadowed a pediatrician at a local hospital to find out more about the development of cognitive learning. Communication and interaction with the children and their parents helped hone my interpersonal skills in a new environment. Through discussions with the doctors and my own observations, I was intrigued to discover the different developmental stages of child behavior and how it relied very much on their innate gut responses more than reasoning or anything else. When I volunteer with Burmese refugee children who come weekly to my school, it is important for me to recognise the level of their learning abilities in order to organise educational activities suitable for them. Although language and cultural barriers make it more challenging, being able to make an impact in their lives is truly rewarding.

By constantly being active in various cognitive activities, I allow my brain to retain its neuroplasticity and improve my everyday life. I am involved in cross country, badminton, taekwondo and also serve as the captain of my school’s basketball team. I embrace my creative side as yearbook designer and occasionally writing press articles for newspapers. I am also part of the school’s string ensemble and performed in various shows and concerts in and out of school. My engagement in the student council as senior committee leader and the organising committee of my school’s first MUN conference allowed me to develop my time management and leadership skills.

I wish to pursue a research career in neuroscience in order to explore the myriad of other possibilities of the brain. Besides understanding neurological disorders such as Alzheimer’s, I believe that greater research into the brain’s potential of enhancing learning and behaviour can also help advance the lives of the neurologically healthy.

DISCLAIMER : The personal statements on this site are strictly meant as a starting point to give an idea of how successful personal statements look like. There is no surefire formula to writing good personal statements.  COLLEGELAH IS STRICTLY AGAINST PLAGIARISM OF ANY KIND . UCAS employs a plagiarism check system that checks applicants’ work against other published writing so please DO NOT PLAGIARISE .

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Creative Neuroscience Personal Statements for Opportunities

Table of Contents

Are you considering a career in neuroscience? You may wonder how to write an effective neuroscience personal statement.

An excellent personal statement can be the difference between acceptance and rejection regarding your application for a job or college program. To help you get started, here’s an overview of what makes strong neuroscience personal statements and tips on how to craft yours.

What Is Neuroscience?

Neuroscience is the study of the nervous system, which includes the brain and all its functions. Neuroscientists investigate how different parts of the nervous system work together to produce thought, emotion, behavior, and other mental processes. In addition to researching neuroscience topics, neuroscientists also design treatments for neurological disorders.

Neuroscience Programs to Research

The field of neuroscience includes many different areas to research;

  • Brain anatomy and physiology
  • neurochemistry
  • neuroimaging
  • Neuropsychology, and more.

Depending on your interests, you should emphasize specific research topics in your personal statement .

What to Include in Your Neuroscience Personal Statement

The first thing you want to do when composing a neuroscience personal statement is to demonstrate your knowledge of the field. You should explain why you are pursuing this career path and discuss your experience. Explain what has driven you to pursue science as a profession. List courses, internships, or research experience that have prepared you for a career in neuroscience.

It’s also vital to demonstrate your enthusiasm for the field. Discuss any unique experiences or challenges that have helped shape who you are today. Talk about how these experiences have shaped your passion for science, what makes them relevant to neuroscience, and your future goals.

You should also highlight any awards or recognition you’ve received in the field, such as scholarships or research grants. This will demonstrate your commitment to the subject and show a track record of success .

Finally, include why you are a good fit for the program or job. Talk about how your experience and skills can contribute to their team and what unique value you can bring to them.

Tips on Writing a Neuroscience Personal Statement

Writing a Neuroscience Personal Statement

Now that you know what to include in your neuroscience personal statement, here are some tips on how to write an effective one:

  • Write clearly and concisely – avoid long-winded sentences and keep your language simple but direct.
  • Proofread thoroughly before submitting – make sure there are no grammar or spelling mistakes;
  • Be honest and reflective – make sure to be authentic in your writing and don’t exaggerate;
  • Make it personal – avoid generic statements and focus on the things that make you unique;
  • Tailor it for each application – customize your statement for each job or program you’re applying to.

Examples of Neuroscience Personal Statements

I have been fascinated by neuroscience’s complexities since I was a child. My interest in this field has only strengthened over time, and now I am determined to pursue a career in it. During college, I completed courses in neurophysiologist and neural networks. I also did a research project on the effects of food deprivation on cognitive performance. Additionally, I volunteered at my local hospital’s neurology department and gained invaluable hands-on experience. These experiences have fully prepared me for a career in neuroscience. It will help me contribute significantly to any team or organization I join.

My passion for neuroscience began when I was studying biology in high school. After enrolling in a neuroscience class, I realized that the complexity and breadth of the field genuinely intrigued me. Since then, I have completed a bachelor’s degree in neuroscience, and since graduating, I have researched at two renowned institutions. My work has earned me several awards and recognitions, including a scholarship from the National Science Foundation. In addition to my scientific experience, I have also worked as a mentor for science students. This has developed my leadership skills. My knowledge and experience make me an ideal candidate for any neuroscience-related position or program.

I have been passionate about neuroscience since I was in high school. After taking an advanced class on the subject, I knew this was the field for me. Since then, I’ve completed a degree in neuroscience and taken part in several research projects. This is where I worked to understand the functioning of the human brain better. My work has earned me awards from two universities and recognition from prestigious organizations such as the American Academy of Neurology. I have also volunteered at a local hospital’s neurology department to gain practical experience in my area of interest. With my knowledge, experience, and enthusiasm for neuroscience, I am confident I can excel in any role or program related to this field.

I have been interested in neuroscience since I was a child and this interest has only grown stronger over the years. During my undergraduate studies, I took courses on neural networks and neuropsychology. I completed an honors’ thesis project in which I studied the effects of food deprivation on cognitive performance. My research earned me recognition from a number of well-respected organizations in the field, including the Society for Neuroscience. Additionally, I also volunteered at a local hospital’s neurology department where I gained hands-on experience. With my knowledge, experience and passion for neuroscience, I am confident that I can make significant contributions to any team or organization I join.

Template to Try

My passion for neuroscience began when ___________. After completing my _(degree)_ in the field, I have gone on to work/research at _____ and received a number of awards and recognitions. Additionally, I have also volunteered/mentored at ____ where I developed valuable skills. With my knowledge, experience, and enthusiasm for neuroscience, I am confident that I can excel in any role or program related to this field.

Writing a solid neuroscience personal statement can be difficult, but careful thought and preparation can help set you apart from other applicants . Follow these tips to ensure your statement stands out and showcases why you’re the perfect candidate for the job or program! Good luck!

Creative Neuroscience Personal Statements for Opportunities

Abir Ghenaiet

Abir is a data analyst and researcher. Among her interests are artificial intelligence, machine learning, and natural language processing. As a humanitarian and educator, she actively supports women in tech and promotes diversity.

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Neuroscience Personal Statement – Sample For Graduate School

EssayEdge > Blog > Neuroscience Personal Statement – Sample For Graduate School

My long-term goal is to dedicate myself to the research field of neuroscience. In order to achieve this goal, I hope to acquire my Ph.D. at Mt. Sinai School of Medicine starting in the fall of 2000.

In 1992, I obtained my MA degree in Molecular Microbiology from Indiana University, Bloomington. At I.U., I received intensive training by Dr. Roger Innes in experimental design, logical thinking, and molecular genetics techniques. After I graduated from I.U., I became a lab supervisor in the clinical cytogenetic laboratory at Tzu Chi College of Medicine, Taiwan. The lab is part of TCCM’s newly established genetic research team directed by Dr. Ming-Liang Lee. My responsibilities at the lab included training lab technicians, improving testing accuracy by consistently improving technical skills and knowledge, and managing the lab’s day-to-day operations. At TCCM, I also taught several fundamental biology courses, including general biology, cell biology, and medical genetics laboratory.

After five years of working, I decided to pursue more advanced research training in the latest techniques of microbiology. Since the fall of 1998, I have been taking several Ph.D.-level courses at New York University . I have performed very well in my studies there, which have been supported by a fellowship from Taiwan’s National Science Council. My courses at NYU are Biochemistry I and II, Molecular Principles of Evolution, Cell Biology, Molecular Controls of Organism Form and Function, Neuroimmunology Journal Club, and Physiology Basis of Behavior. I am also researching in Dr. Joseph LeDoux’s lab for credit. At this lab, I have been using immunohistochemistry to detect the activation of track receptors in rat brains after fear conditioning. One of the tracks, trkB, responds to BDNF, which is related to synaptogenesis and LTP induction in the processes of learning and memory. My results have shown that the phosphorylation peak of trk appears in the hippocampal CA1 area 24 hours after fear conditioning. Further blocking experiments using trk antagonist need to be performed in order to confirm this result.

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My laboratory experience has triggered my strong interest in studying cellular and molecular mechanisms underlying neurological diseases. The majority of patients with these diseases have chromosomal and genetic abnormalities. Most genetic diseases lead to neurological symptoms, and several neurological diseases are associated with strong genetic predispositions. The genetic defects associated with Alzheimer’s Disease, alcoholism, Fragile-X Syndrome, Neurofibrmatosis, and Parkinson’s Disease have already been mapped. However, the links between genes, gene products, neuronal circuits, brain functions, and diseases are still unclear. I am eager to help uncover these links.

I think that Mt. Sinai’s Ph.D. program perfectly suits my interests. The faculty includes experts in several divisions of neuroscience. There is an especially large group studying neurological diseases. The group uses various approaches, animal models, and behavioral paradigms to search for the causes of diseases on the molecular, cellular, physiological, and system levels. I am particularly interested in working in Dr. John Morrison’s lab, which studies cortical organizations, glutamate receptors, and neurodegenerative disorders; Dr. Patrick Hof’s lab, which uses comparative neuroanatomy to study aging; Dr. Giulio Pasinetti’s lab, which studies cyclooxygenase and inflammation in Alzheimer’s Disease; and Dr. Charles Mobbs’s lab, which uses molecular, histological, behavioral, and electrophysiological methods to study basic mechanisms underlying metabolic diseases and aging.

Mt. Sinai School of Medicine also attracts me because of its location in an extremely nice area of Manhattan. In addition, the strong collaboration between its neuroscience program and its other departments, its affiliated hospital, and many other outstanding New York laboratories will enable me to receive much technical and academic support.

In order to sponsor my Ph.D. education, I have obtained a competitive Ph.D. fellowship from the Buddhist Compassion Relief Tzu-Chi Foundation, the largest nonprofit organization in Taiwan. The foundation is dedicated to helping needy all over the world, regardless of age, sex, race, and religion. Over the past decades, it has provided worldwide relief and assistance. Its missions focus on charity, medical care, education, and international relief. The founder, Master Chang Yang, was once nominated for the Nobel Peace Prize. The foundation will support my Ph.D. education for at least four years.

After completing my Ph.D. education, I plan to continue my research and teaching in neuroscience. Thus far, most of the detailed work in studying neurological disease has of necessity been performed in experimental animal systems. However, the progress of human genome mapping might eventually make it possible to test whether the disease mechanisms discovered in animals function in comparable ways in humans. Consequently, in the future, I hope to apply my knowledge of the genes and proteins involved in neurological diseases to develop pharmacological treatment or genetic therapies. I am confident that one day we will have effective drugs to prevent memory loss or aging. We may even be able to cure currently intractable neurological diseases through gene therapies, either in utero or in live humans.

I am confident that Mount Sinai School of Medicine’s graduate program will enable me to successfully meet my goals. I also believe that if I am accepted to your Ph.D. program, I will contribute greatly to Mount Sinai’s learning environment.

If the paper you plan to submit looks similar to this sample, you can order a graduate school personal essay edit. This neuroscience graduate essay sample has a good structure, flow, and style, but some aspects need improvement. You can check our before and after editing examples to realize why editing is essential. We are waiting for your request!

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  • CAREER FEATURE
  • 23 April 2021

Sell yourself and your science in a compelling personal statement

Andy Tay is a science writer in Singapore.

You can also search for this author in PubMed   Google Scholar

You have full access to this article via your institution.

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Personal statements — essays highlighting personal circumstances, qualities and achievements — are used extensively in science to evaluate candidates for jobs, awards and promotions. Five researchers offer tips for making yours stand out in a crowded and competitive market.

STEVE OH: Convey personal qualities beyond academic interests

Steve Oh is director of the Stem Cell Processing Group at the A*STAR Bioprocessing Technology Institute in Singapore.

As a principal investigator, I have read a good number of personal statements from students applying for science scholarships and jobs. The ones that stand out recount the applicant’s biography, bringing out their character as well as their professional qualities.Personal statements are often centred on academic and research achievements. But, in my opinion, a good scientist should also demonstrate social skills, be interested in making an impact on society through, for example, entrepreneurship, and have awareness of the world outside the country they live in. Memorable personal statements tend to bring out ‘soft’ skills, such as having macro-level thinking abilities and awareness of the impact that science can have on society.

personal statement related to neuroscience

Careers Collection: Publishing

To achieve this balance of professional and personal, consider two elements. First, explain your motivations to pursue a scientific career. These might include a family illness, an inspiring talk by a scientist, or great mentorship from a colleague. Second, describe how you have gone out of your way to get experience in science, such as proactively seeking opportunities for a laboratory internship, or what you have learnt from overcoming difficulties with your experiments. This information brings out qualities, such as curiosity and perseverance, that are crucial to being a good scientist.

I vividly remember the personal statement of one of my PhD students. He described his struggle with having only one healthy kidney — and how, despite this, he continued to do sports like rock climbing. He also wrote about how he did badly in his undergraduate studies: he had to take a year off to recharge before returning to school and excelling. His story shows resilience and honesty — traits that I love in a researcher.

SILVIA KARIUKI: Do not be afraid to defend your decisions

Silvia Kariuki is a postdoctoral fellow at the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Programme in Kilifi.

When I was planning to return to Kenya, where I grew up, to start a postdoctoral project, fellow researchers, friends and family members all asked why I was choosing to go back. They felt my career would suffer because Kenya’s scientific infrastructure is not as advanced as that in the United States, where I spent 13 years working and completing my undergraduate and PhD degrees.

Two years into my return to Kenya, when writing my personal statement for the Wellcome International Training Fellowship to follow up on my postdoctoral project, I explained that the Kenya Medical Research Institute–Wellcome Trust Research Programme in Kilifi could provide a good research environment for me. I would be able to study human genetic variants that confer protective effects against severe malaria infection, and my research would have a real-world impact by informing the production of malaria therapies. In my personal statement, I wrote that I wanted to pursue my scientific career in Kenya despite the scepticism I had faced — and it convinced the fellowship committee that I had thought deeply about my career move.

I also seek advice from mentors when writing a personal statement. I usually send mine to two to three senior scientists who have had more experience writing them and who have been on review committees for fellowship applications. One suggestion I usually get is to be ‘more human’. The judges would like to hear your personal voice and read about your motivation, even if these might be unconventional.

KELLY CLANCY: Use stories to show who you are

Kelly Clancy is a postdoctoral fellow in neuroscience at University College London.

Stories can make a personal statement stand out. It’s hard, of course — I’ve heard colleagues say it’s a trope for neuroscience-related personal statements to open with something like “I got interested in neuroscience after seeing my grandmother suffer from Alzheimer’s.” But I think that cynicism is unfair: it’s a beautiful impulse to get into science for a personal reason, and having a personal connection to science can drive important new insights.

I included the story that inspired the project I’d proposed in my application to the Branco Weiss postdoctoral fellowship. My best friend from high school had lost three limbs to an improvised explosive device while serving as a medic in Afghanistan. I described how this incident led to my interest in the field of neuroprosthetic devices that can restore motor capabilities, and the shortcomings I wanted to address with my work.

My advice for writing a personal statement is to not get bogged down in technical details. Don’t just focus on what you want to study — explain why. Demonstrate how you think. What led you to do the work or research you’ve undertaken so far? What are the questions that drive you and your science, and why are they important? Perhaps most importantly (and this is for all of us, not just those writing personal statements): ask, “What drives my science? Is it a reflection of my ego, wanting to be right or smart and to get high-profile publications? Or is it an extension of my will to do good in the world, my curiosity and my love of understanding?” The world is full of questions and problems to solve. Using stories in personal statements can help applicants to explain what scientific questions they care about, and why they matter.

personal statement related to neuroscience

Collection: the PhD

With the support from the Branco Weiss Fellowship, my colleagues and I have since developed neuroprosthetic techniques that were just published 1 and used these methods to explore interesting basic neuroscience questions and less-invasive neurosprosthetic interfaces.

WEI GAO: Demonstrate ambition and don’t exaggerate

Wei Gao is an assistant professor of mechanical engineering at the California Institute of Technology in Pasadena.

Wei Gao sits on the bleachers.

Wei Gao, an assistant professor of mechanical engineering. Credit: Wei Gao

A personal statement should highlight your aspirations and dreams. A CV can list all your publications, but they won’t all be read thoroughly, and members of the selection committee might miss the significance of your work.

Think of a personal statement as a document that complements your CV. I use it to explain the big problems my research is tackling and its impact. In my application to be a World Economic Forum Young Scientist, I described my concerns about worsening mental health in our society and discussed how my research on wearable sensors can improve early diagnosis of mental illness by sensing metabolites such as cortisol, a stress-related hormone, in sweat. It would be difficult to explain my aspirations clearly in a short, typically list-based, CV. In a personal statement, I can demonstrate my ambition in greater detail.

A good personal statement should avoid exaggerating your contribution. This is especially true for a multi-author paper on which you didn’t have a leading role. Focus on the work that you led and to not overstate your contributions to your field. Even if your contribution was significant, being humble in a personal statement is a good quality. Research is a culmination of the efforts of many researchers, and is never attributable to just one person.

ABHIMANYU VEERAKUMARASIVAM: Break the essay down and tailor it to your audience

Abhimanyu Veerakumarasivam is dean of the School of Medical and Life Sciences at Sunway University Subang Jaya in Malaysia.

Prof Abhi holding a microplate with biological samples for analysis in his research laboratory.

Abhimanyu Veerakumarasivam in the lab. Credit: Sunway University

One way to simplify the writing process is to break your personal statement down into several key elements, including who you are, what you have accomplished, why you are applying for a role or award and how you will contribute to the organization.

When I was organizing the Association of Southeast Asian Nations (ASEAN) Science Leadership Programme from 2017 to 2019, my committee and I divided the application statement into a few questions focused on the ‘who, what, why and how’, which would help applicants to better structure their essays. I found this format particularly useful because, in Asia, our default culture is to not stand out, and many qualified candidates might be too shy to share their personal stories or too humble to share their achievements.

I found that creating a more defined structure around the personal statement allowed applicants to reflect on the experience they have gained from working in the region, which has many low-income countries and little investment in science. I would not always get these details in an open-ended personal essay.

One candidate discussed the huge disparities in science in the ASEAN region and his desire to bridge the gaps. By doing so, the candidate demonstrated that he had a good awareness of his environment and the unique challenges of working in that setting while highlighting his willingness to take action to bridge the gaps.

Applicants should also tailor their personal statements to their audience. For instance, students applying to graduate schools and scholarships will often send generic personal statements with their applications. If applicants want an academic institution to invest in them, then their personal statements need to reflect a genuine interest in the organization they’re applying to. The candidates with better statements usually include details of labs they are interested in working in and specifics about research topics they find fascinating.

Nature 593 , 153-155 (2021)

doi: https://doi.org/10.1038/d41586-021-01101-z

These interviews have been edited for length and clarity.

K. B. Clancy et al. Neuron 109 , 677–689 (2021).

Article   PubMed   Google Scholar  

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Personal Statement for Grad School

Hello Everyone,

I am writing in hopes of receiving advice concerning my personal statement for graduate study in neuroscience from those who have been through the process themselves. I am finding this portion of the application to be by far the most difficult. Any advice at all would be greatly appreciated as I am really struggling with this. Let me give you some background about me.

I have 2 undergraduate degrees from a small state school - one in chemistry and one in psychology. I've worked in two different visual neuroscience labs - one project applying fractal analysis to eye movement, and another looking at how object perception and fractal complexity underlie natural scene aesthetics. Before that I spent a year and a half working on a computational chemistry project as part of a protein-research lab. My immediate goal in attending graduate school for neuroscience is to study vision at the systems level. My long term goal is to be a career researcher and college professor in visual neuroscience. I'm most interested in studying the neurophysiology, neural circuitry, and computational properties of the visual system (human or animal).

I have experience using tobii eye-tracker and TobiiStudios, MATLAB, SPSS, Python Programming, performing cognitive/behavioral testing of human subjects, many different chemistry softwares, and general biochem lab techniques like PCR, plasmid construction, western blots, cell culturing, microscopy.

Does anyone have advice on how to tie my research experience into my future research goals? I keep writing and writing, but I feel like I'm rambling and all over the place.

Thanks in advance for your help!

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Exploring how the brain works is the main goal behind neuroscience. In this course, students are given the chance to understand the workings of the mind as well as the best treatments for various psychiatric and neurological disorders that afflict people. Research, analysis, and practical applications of theories and principles governing neuroscience will be made available to students in order for them to acquire the necessary knowledge and tools to be able to contribute their expertise in this field. For those who want to pursue this course, here are a few requirements that you need to submit:

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bioRxiv

Exosomes can modulate the early hyperexcitability in cortical neurons with ASD-associated Shank3 mutation.

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Shank3, a scaffolding protein, is critical for synaptic structure and function, particularly for the formation and maintenance of dendritic spines. Shank3 mutations are strongly implicated in autism spectrum disorder (ASD) and related neuropsychiatric conditions such as Phelan-McDermid Syndrome (PMS) also known as the 22q13.3 deletion syndrome. Previous work has recognized early hyperexcitability in cortical neurons derived from ASD patients with various gene mutations as a potential common endophenotype. In this study, we examined the effects of exosomes extracted from several cell types on the neurophysiological properties of cortical neurons derived from Shank3 (c.3679insG mutation) induced pluripotent stem cells (iPSCs). First, we sought to understand the implications of exosome-based intercellular communication on the neurophysiology of Shank3 mutant and control neurons by switching their respective exosomes. We found that while control neuron-derived exosomes do not change the neurophysiology of Shank3 neurons, the Shank3 neuron-derived exosomes transfer the early hyperexcitability and other ASD-related phenotypes to control neurons. Next, we also explored the therapeutic potential of mesenchymal stem cells (MSC) and iPSC-derived exosomes from healthy donors in the Shank3 cortical neurons. We demonstrate that both MSC and iPSC-derived exosomes rescue the early hyperexcitability and accelerated maturation of Shank3 neurons. Proteomic analysis of exosomes derived from Shank3 mutant and control neurons, as well as from exosomes derived from MSCs and iPSCs, revealed distinct protein cargoes that may cause changes in the neurophysiological properties of the recipient neurons. Our results hence provide novel insights into the pathophysiology of ASD emphasizing the importance of exosomes in intercellular communication and their potential to influence intrinsic and network properties of neurons. Moreover, our findings support the need for further exploration of exosome-based interventions as potential therapeutics for treating neurodevelopmental disorders.

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Nigerian Man Arrested in Alleged $10 Million Pandemic Unemployment Assistance Fraud Scheme

BOSTON – A Nigerian man was arrested on Aug. 13, 2024 upon arriving at John F. Kennedy International Airport in New York City on charges that he, and others, conspired to fraudulently obtain at least $10 million in COVID-19 unemployment benefits.

Yomi Jones Olayeye, a/k/a “Sabbie,” 40, of Lagos, Nigeria, is charged with one count of wire fraud conspiracy, one count of wire fraud and one count of aggravated identity theft. He made an initial appearance in the Eastern District of New York on Aug. 14, 2024 and will appear in federal court in Boston tomorrow.  

According to the charging document, between March and July 2020, Olayeye and others defrauded three pandemic assistance programs administrated by the Massachusetts Department of Unemployment Assistance and other states’ unemployment insurance agencies: traditional unemployment insurance (UI), Pandemic Unemployment Assistance (PUA) and Federal Pandemic Unemployment Compensation (FPUC). 

Specifically, Olayeye and his co-conspirators allegedly used personally identifiable information (PII) they purchased over criminal internet forums to apply for UI, PUA and FPUC – falsely representing themselves to be eligible state residents affected by the COVID-19 pandemic. Olayeye and his co-conspirators allegedly used the same fraudulently obtained PII to open U.S. bank and prepaid debit card accounts to receive the assistance payments. It is also alleged that Olayeye and his co-conspirators recruited U.S.-based account holders to receive and transfer the fraud proceeds via cash transfer applications. Olayeye and his co-conspirators then allegedly used the fraudulent proceeds to purchase Bitcoin via online marketplaces. It is further alleged that Olayeye and his co-conspirators concealed the conspiracy’s connection to Nigeria by leasing Internet Protocol addresses assigned to computers located in the United States for use in the fraudulent transactions. 

In total, Olayeye and his co-conspirators allegedly applied for at least $10 million in fraudulent UI, PUA and FPUC from Massachusetts, Hawaii, Indiana, Michigan, Pennsylvania, Montana, Maine, Ohio and Washington and received more than $1.5 million in assistance to which they were not entitled.  

The charges of wire fraud and wire fraud conspiracy provide for a sentence of up to 20 years in prison, three years of supervised release, a fine of $250,000 or twice the gross gain or loss, forfeiture and restitution. The charge of aggravated identity theft calls for a mandatory minimum sentence of two years in prison to be added to any sentence imposed on the wire fraud charge. Sentences are imposed by a federal district court judge based upon the U.S. Sentencing Guidelines and statutes which govern the determination of a sentence in a criminal case. 

Acting United States Attorney Joshua S. Levy; Special Agent in Charge Andrew Murphy of the U.S. Secret Service Boston Field Office; Jonathan Mellone, Special Agent in Charge of the Department of Labor, Office of Inspector General; and Jodi Cohen, Special Agent in Charge of the Federal Bureau of Investigation, Boston Division made the announcement today.  Assistant U.S. Attorney Seth B. Kosto, Deputy Chief of the Securities, Financial & Cyber Fraud Unit is prosecuting the case.

On May 17, 2021, the Attorney General established the COVID-19 Fraud Enforcement Task Force to marshal the resources of the Department of Justice in partnership with agencies across government to enhance efforts to combat and prevent pandemic-related fraud. The Task Force bolsters efforts to investigate and prosecute the most culpable domestic and international criminal actors and assists agencies tasked with administering relief programs to prevent fraud by augmenting and incorporating existing coordination mechanisms, identifying resources and techniques to uncover fraudulent actors and their schemes, and sharing and harnessing information and insights gained from prior enforcement efforts. For more information on the department’s response to the pandemic, please visit https://www.justice.gov/coronavirus and https://www.justice.gov/coronavirus/combatingfraud .       Anyone with information about allegations of attempted fraud involving COVID-19 can report it by calling the Department of Justice’s National Center for Disaster Fraud (NCDF) Hotline via the NCDF Web Complaint Form .

The details contained in the charging documents are allegations. The defendant is presumed innocent unless and until proven guilty beyond a reasonable doubt in a court of law. 

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Journal of Neuroscience

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Dense and persistent odor representations in the olfactory bulb of awake mice

Recording and analysis of neural activity is often biased toward detecting sparse subsets of highly active neurons, masking important signals carried in low magnitude and variable responses. To investigate the contribution of seemingly noisy activity to odor encoding, we used mesoscale calcium imaging from mice of both sexes to record odor responses from the dorsal surface of bilateral olfactory bulbs (OBs). The outer layer of the mouse OB is comprised of dendrites organized into discrete “glomeruli”, which are defined by odor receptor-specific sensory neuron input. We extracted activity from a large population of glomeruli and used logistic regression to classify odors from individual trials with high accuracy. We then used add-in and drop-out analyses to determine subsets of glomeruli necessary and sufficient for odor classification. Classifiers successfully predicted odor identity even after excluding sparse, highly active glomeruli, indicating that odor information is redundantly represented across a large population of glomeruli. Additionally, we found that Random Forest feature selection informed by Gini Inequality (RFGI) reliably ranked glomeruli by their contribution to overall odor classification. RFGI provided a measure of “feature importance” for each glomerulus that correlated with intuitive features like response magnitude. Finally, in agreement with previous work, we found that odor information persists in glomerular activity after odor offset. Together, our findings support a model of olfactory bulb odor coding where sparse activity is sufficient for odor identification, but information is widely, redundantly available across a large population of glomeruli, with each glomerulus representing information about more than one odor.

Significance statement This study leverages meso-scale imaging and machine learning to investigate how odor information is first represented in the brain. Typically, recordings of neuronal activity focus on active individual cells, potentially overlooking broader variations in neuronal responses across populations. Our results demonstrate that a considerable amount of olfactory information is redundantly distributed across a large proportion of olfactory bulb glomeruli. Even after excluding a majority of glomeruli, odor identification remained possible. These findings indicate that, although a few glomeruli are sufficient for odor recognition, an abundance of additional information is represented across a broad population. Understanding how the brain manages redundant olfactory information will shed light on its adaptive mechanisms for navigating diverse real-world circumstances and responding to fluctuating internal states.

The authors report no conflict of interest.

This work was supported by the NIH through NINDS and the BRAIN Initiative (U01 NS111692 to BRA and PP) and NIDCD and the BRAIN Initiative (R00DC019505 to EHM).

↵ * These authors contributed equally to this work

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Biomedical science/neuroscience personal statement example.

The limitless potential of the life sciences and the opportunity for world-changing breakthroughs are both exciting and compelling to me. Upon hearing about a disease for the first time, I am eager to find out more about the precise ways in which it affects the body, which has led me to spend much time researching the details of various diseases. My desire to understand life on a deeper, biological level and to be involved in the analysis and diagnosis of disease first inspired me to pursue a career in medical science. The prospect of obtaining a diverse role in the medical field that holds a strong link to human biology makes it a natural path for me to take.

I am currently enjoying participating in a six week biomedicine course at the Newcastle Centre for Life. It has given me a clearer insight into the numerous disciplines within biomedical science and taught me about the involvement of various processes, such as microscopy and the handling of small patient specimens. This has given me a sense of the importance of attention to detail, a quality that I feel I naturally possess. The course has also involved practical aspects; an ultrasound machine was used to directly observe blood vessels within the neck of a participant, providing an applied example of the complexity of human anatomy. Reading has additionally played a large part in advancing my interest in biomedicine and I developed a particular interest in neuroscience upon reading 'The Man Who Mistook His Wife for a Hat' by Oliver Sacks. This book opened my eyes to the progressive nature of neuroscience and the intriguing occurrences of such unique cases within the field of neurology.

At A-Level, my subject choices are varied, indicating my well-rounded capabilities, but Biology has without a doubt provided me with the most enjoyment. The first AS unit entitled 'Biology and Disease' seized my interest immediately and I most recently completed Unit 5, my favourite topics being muscle contraction and the nervous system, anatomical topics with undoubted links to biomedicine. Another chapter in Unit 5 was devoted to DNA technology, highlighting the technological advances in the medical field and holding particular relevance to my course choice due to the large amount of laboratory work that is based on the use of highly technical equipment. English Literature A-Level, although not science-related, has enabled me to write concisely and coherently. It has also largely developed my ability to be analytical and to successfully debate varying opinions and ideas. Psychology not only complements my other subject choices by being both scientific and essay-based, but it has provided me with abundant knowledge of research methodology, a particularly beneficial skill in science related sectors.

Aside from my academic studies, last year I was a member of the Sixth Form Student Council, which involved organising charity events within the school as well as running the Leavers' Ball and Yearbook, tasks which demonstrate reliability and heightened my independence and organisational skills. My resilience was tested while completing the Gold Duke of Edinburgh Award expedition, as this was the section of the award that was the furthest from my comfort zone. Through completing it I have become more self-sufficient and developed my communication skills by working in a team, as well as proving that with determination and ambition, I can rise to formerly daunting challenges. I am also an NHS Mealtime Volunteer, working largely with elderly patients, many of whom suffer from dementia. Although not directly linked to biomedical science, this has heightened my interest in conditions that affect the brain, whilst demonstrating my ability to balance additional responsibilities with A-Level work. Seeing the debilitating effects of such a disease has ultimately confirmed my wish to play an essential role in the processes that lead to the cure or treatment of disease.

Profile info

This personal statement was written by Whetters for application in 2014.

Whetters's university choices University of Bristol The University of Nottingham The University of Manchester University of Leeds Nottingham Trent University

Green : offer made Red : no offer made

Whetters's Comments

I applied to Biomedical Science at three universities and Neuroscience at two.

University of Manchester - Biomedical Science - interviewed then offer received of AAB University of Leeds - Medical Science - offer received of AAA Bristol University - Neuroscience - offer received of AAB University of Nottingham - Neuroscience - offer received of AAB Nottingham Trent - Biomedical Science - offer received of 300 UCAS points

I am doing a third year of sixth form and my predicted grades for the end of this year are AAB.

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